Comparison of Efficacy of Oral Fluconazole Versus Oral Itraconazole in the Treatment of Pityriasis Versicolor

NCT ID: NCT06922344

Last Updated: 2025-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE4

Total Enrollment

106 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-01

Study Completion Date

2025-12-31

Brief Summary

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This study compares the efficacy of two drugs, namely flucanazole and itraconazole for the treatment of a common fungal infection of skin.

Detailed Description

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Pityriasis versicolor is a common fungal infection of the superficial skin layers. Avalible treatment options include topical and systemic drugs. fluconazole and itraconazole are commonly used systemic agents. The aim of this study is to compare the efficacy of the two systemic drugs.

Conditions

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Pityriasis Versicolor

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Group A, Fluconazole group

Group A consists of patients in whom oral fluconazole is given in dose of 300mg once weekly for 2 weeks.

Group Type EXPERIMENTAL

Fluconazole

Intervention Type DRUG

Oral fluconazole prescribed to group A

Group B, Itraconazole group

Group B consists of patients in whom oral Itraconazole is given in dose of 100mg Twice for 5 days.

Group Type EXPERIMENTAL

Itraconazole

Intervention Type DRUG

Oral itraconazole prescribed to Group B

Interventions

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Fluconazole

Oral fluconazole prescribed to group A

Intervention Type DRUG

Itraconazole

Oral itraconazole prescribed to Group B

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* All cases of Pityriasis versicolor

Exclusion Criteria

* Patients with history of chronic renal or liver disease, malignancy , or undergoing any kind of chemotherapy or radiotherapy or having cardiac conduction abnormalities.
* Patients who received any anti-fungal therapy in the last one month.
* Pregnant or lactating women.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Khyber Teaching Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hajira Amin

Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Khyber Teaching Hospital

Peshawar, KPK, Pakistan

Site Status RECRUITING

Countries

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Pakistan

Facility Contacts

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Hajira Amin

Role: primary

0346 9075951

Other Identifiers

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84/DME/KMC

Identifier Type: -

Identifier Source: org_study_id

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