App Impact on Quality of Life and Symptoms in PCOS

NCT ID: NCT06912594

Last Updated: 2025-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-02

Study Completion Date

2025-09-30

Brief Summary

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This study investigates the influence of a PCOS app on the quality of life and symptoms of individuals with polycystic ovary syndrome (PCOS). The intervention group can use the app over the study period of twelve weeks in addition to care-as-usual (CAU). In the control group, this is compared with no use of the PCOS-App for a twelve-week period, that is, care-as-usual only/ continuation of the current treatment (waitlist design). The aim is to evaluate the effectiveness of the app and to gain insights for the design of future studies. The study is expected to last seven months and include 220 participants.

Detailed Description

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The study aims to investigate the effect of a PCOS app on quality of life and symptoms of individuals with polycystic ovary syndrome (PCOS). PCOS is a widespread and distressing health problem that can significantly affect quality of life and well-being of affected individuals. Research into digital health applications has shown the potential to provide innovative solutions to improve care and self-management of chronic conditions.

The present study is designed as a single-blind, two-arm, randomised controlled trial in which participants will either receive the PCOS app over a 12-week period in addition to care-as-usual (intervention group) or only care-as-usual as typically available (control group). The study will be conducted online. The aim is to evaluate the effectiveness of the app by analysing various questionnaires as endpoints. The primary endpoint is the Polycystic Ovary Syndrome Questionnaire (PCOSQ-G). The questionnaires/endpoints will be completed at T0 (baseline) and after 12 weeks. Statistical analyses will be conducted using R and SPSS. Exploratory evaluations of change scores in the relevant questionnaires will be performed.

Overall, this study aims to provide important insights into whether and to what extent a PCOS app can have a positive impact on the quality of life and symptoms of women with PCOS.

Conditions

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Polycystic Ovary Syndrome (PCOS)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomised controlled trial
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors

Study Groups

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Control Group

Control group has access to care-as-usual only.

Group Type NO_INTERVENTION

No interventions assigned to this group

Intervention Group

The intervention group has access to the PCOS app and its functions in in addition to care-as-usual

Group Type EXPERIMENTAL

PCOS-App

Intervention Type DEVICE

The PCOS-App helps to implement multimodal self-help measures in the daily lives of PCOS patients through various functions such as symptom diary and interactive exercises.

Interventions

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PCOS-App

The PCOS-App helps to implement multimodal self-help measures in the daily lives of PCOS patients through various functions such as symptom diary and interactive exercises.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Legal capacity
* Resident in Germany
* Female gender
* Age ≥18 years up to 65 years
* Diagnosed and medically confirmed Polycystic Ovary Syndrome (E28.2)
* Ownership of a smartphone with a compatible iOS or Android version and the ability to operate it
* Internet access and an email address for registration, app usage, and completing questionnaires
* Willingness to complete questionnaires online
* Motivation to use the app regularly
* Sufficient knowledge of the German language

Exclusion Criteria

* Changes in hormone therapy within eight weeks prior to the start of the study and/or planned within the next 12 weeks
* Changes in treatment with metformin within eight weeks prior to the start of the study and/or planned within the next 12 weeks
* Current treatment with medications for obesity (e.g., liraglutide, orlistat)
* Changes in treatment with anti-androgens (e.g., spironolactone, cyproterone acetate, flutamide) within eight weeks prior to the start of the study and/or planned within the next 12 weeks
* Pregnancy or breastfeeding
* Current hormonal fertility treatment
* Changes in treatment with psychotropic medications within eight weeks prior to the start of the study and/or planned within the next 12 weeks
* Current psychotherapeutic treatment
* Previous or current access to the Endo-App or other digital health applications (DiGAs)
* Current participation in other clinical studies
* Current nutritional counseling according to §20 SGB V or nutritional therapy according to §43 SGB V, or participation in weight reduction programs
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Endo Health GmbH

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Endo Health GmbH

Chemnitz, Saxony, Germany

Site Status

Countries

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Germany

Central Contacts

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Teresa Götz, M.Sc.

Role: CONTACT

+49 371 33560304

Facility Contacts

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Teresa Götz, M.Sc.

Role: primary

+49 371 33560304

Other Identifiers

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RCT_PilotPCOS

Identifier Type: -

Identifier Source: org_study_id

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