Physical Activity in Persons With Parkinson's Disease

NCT ID: NCT06901869

Last Updated: 2025-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-25

Study Completion Date

2026-12-31

Brief Summary

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Parkinson's disease (PD) is a leading neurodegenerative health condition in Sweden and a public health concern. Although no cure exists, functional independence and participation in society remain top priorities, and can be achieved through targeted physical activity (PA) interventions. To date, few longitudinal cohort studies have been conducted, using PA as main outcome in therapy research, partly due to the complex nature of predicting and controlling this phenomenon. To help address this knowledge gap, the overall purpose of the future long-term (ActivPARK) study is to enhance knowledge of the evolution of PA behavior, and how it is influenced beyond the disease characteristics using a broad explanatory model, in persons with PD from a diversity of settings in Sweden with the aim of prescribing tailored and personalized interventions to enhance functioning, health, and wellbeing throughout the disease progression and recommend potential health care pathway modifications.

The investigators have just established an expert group, comprising researchers, healthcare professionals, and PD organisations (including persons with PD) and reached consensus on essential priority clinical therapy research questions on PA and methodological considerations. The next phase entails performing a multicentre feasibility/pilot study, further developing and refining the assessment battery and research questions linked to the improved explanatory model for PA and methodology, to inform the definite larger clinical cohort study.

Detailed Description

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Conditions

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Parkinson Disease Physical Inactivity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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People with Parkinson's disease

No intervention

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with Parkinson's disease
* Mild to severe disease severity ( Hoehn \& Yahr 1-4).

Exclusion Criteria

* None
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Lund University

OTHER

Sponsor Role collaborator

Göteborg University

OTHER

Sponsor Role collaborator

Umeå University

OTHER

Sponsor Role collaborator

Region Stockholm

OTHER_GOV

Sponsor Role collaborator

Vastra Gotaland Region

OTHER_GOV

Sponsor Role collaborator

Region Skane

OTHER

Sponsor Role collaborator

Region Västerbotten

OTHER_GOV

Sponsor Role collaborator

Karolinska Institutet

OTHER

Sponsor Role lead

Responsible Party

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Erika Franzén

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Erika Franzén

Role: PRINCIPAL_INVESTIGATOR

Karolinska Institutet

Locations

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Karolinska institutet

Stockholm, Solna, Sweden

Site Status RECRUITING

Countries

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Sweden

Central Contacts

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Compliance Office Karolinska Insitutet

Role: CONTACT

+46852480000

Erika Franzén

Role: CONTACT

+46852488878

Facility Contacts

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Erika Franzén, PhD

Role: primary

+46852488878

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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2024-06332

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

2024-07526-01

Identifier Type: -

Identifier Source: org_study_id

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