Health-economic Assessment of Robot-assisted Bariatric Surgery

NCT ID: NCT06858761

Last Updated: 2025-07-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

482 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-25

Study Completion Date

2028-07-31

Brief Summary

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CONTEXT :

Obesity is a serious disease which affects 17% of the french population. Bariatric and metabolic surgery has demonstrated its efficiency and remains the treatment of reference. Over 40,000 bariatric procedures are performed per year, mainly by laparoscopy ; the robotic approach, historically developed by Intuitive Surgical increases rapidly and accounts for 18% of the procedures in the public system. Whereas the robotic approach has demonstrated its superiority toward laparoscopy for prostatectomies and rectal resections, it still has to be demonstrated for bariatric surgery ; some studies report a decrease rate of complications for complexe procedures and selected patients but the literature remains variable and the benefit of the robot in relation to its high cost must be confirmed.

OBJECTIVES:

To conduct a health-economic assessment (i.e. cost-effectiveness ratio expressed as the additional cost per quality adjusted life-year gained) of the Da Vinci robot in bariatric surgery at 1 year, from the Health Care system point of view.

METHOD :

Randomized (482 patients), controlled, single-blind, multicenter, superiority trial comparing two approaches for primary or revisional bariatric surgery: a group benefiting from a robotic approach and a reference group benefiting from a laparoscopic approach. Data from the trial will be matched via the social security number to the French National Health Insurance Information System (SNDS database) in order to collect care consumption. The quality of life will be assessed using the EuroQol-5 Dimension (EQ5D-5L) questionnaire.

PERSPECTIVES:

This study will have a direct impact on patients care, professional practices and public health policy either by validating the value of the robot in bariatric surgery or conversely, by promoting the laparoscopic approach.

HYPOTHESIS :

Robot-assisted bariatric surgery is more expensive than conventional laparoscopy, but the additional costs associated with the robot are partly offset by a reduction in post-operative complications at 1 year, which should also help to improve patients' quality of life.

Detailed Description

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Conditions

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Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Prospective multicenter randomized, controlled in 2 parallel groups, single-blind, superiority trial comparing 2 modalities of bariatric surgery (first-line or revision):

* Robotic surgical strategy
* Conventional laparoscopic surgical strategy
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Participants
Single-blind study: patient will not be informed of the approach (laparoscopic or robotic) which will be used for their intervention.

Study Groups

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Robot-assisted surgical strategy

Primary bariatric surgery (According to the recommendations of the High Authority of Health: patient with a BMI ≥40 kg/m2 and/or BMI ≥35 kg/m2 associated with at least one comorbidity and/or BMI between 30 and 35 kg/m2 and suffering from type 2 diabetes) or revision bariatric surgery (for complications or side effects of a previous surgery), using a robotic approach.

Group Type EXPERIMENTAL

Robot-assisted surgical strategy

Intervention Type PROCEDURE

Primary or revision bariatric surgery (for complications or side effects of a previous surgery), using a robotic approach. The robot used will be the Da Vinci X or Xi model (depending on the center) from the company Intuitive Surgical.

Visual analog scale

Intervention Type OTHER

All patients will have pain evaluation with visual analog scale

EQ-5D-5L questionnaire

Intervention Type OTHER

All patients will have quality of life assessment with EQ-5D-5L questionnaire

Impact of Weight on Quality of Life (IWQOL) questionnaire

Intervention Type OTHER

All patients will have Quality of life assessment with IWQOL questionnaire

Conventional laparoscopic surgical strategy

Primary bariatric surgery (According to the recommendations of the High Authority of Health: patient with a BMI ≥40 kg/m2 and/or BMI ≥35 kg/m2 associated with at least one comorbidity and/or BMI between 30 and 35 kg/m2 and suffering from type 2 diabetes) or revision bariatric surgery (for complications or side effects of a previous surgery), using a conventional laparoscopic approach.

Group Type ACTIVE_COMPARATOR

Conventional laparoscopic surgical strategy

Intervention Type PROCEDURE

Primary or revision bariatric surgery (for complications or side effects of a previous surgery), using a conventional laparoscopic approach

Visual analog scale

Intervention Type OTHER

All patients will have pain evaluation with visual analog scale

EQ-5D-5L questionnaire

Intervention Type OTHER

All patients will have quality of life assessment with EQ-5D-5L questionnaire

Impact of Weight on Quality of Life (IWQOL) questionnaire

Intervention Type OTHER

All patients will have Quality of life assessment with IWQOL questionnaire

Interventions

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Robot-assisted surgical strategy

Primary or revision bariatric surgery (for complications or side effects of a previous surgery), using a robotic approach. The robot used will be the Da Vinci X or Xi model (depending on the center) from the company Intuitive Surgical.

Intervention Type PROCEDURE

Conventional laparoscopic surgical strategy

Primary or revision bariatric surgery (for complications or side effects of a previous surgery), using a conventional laparoscopic approach

Intervention Type PROCEDURE

Visual analog scale

All patients will have pain evaluation with visual analog scale

Intervention Type OTHER

EQ-5D-5L questionnaire

All patients will have quality of life assessment with EQ-5D-5L questionnaire

Intervention Type OTHER

Impact of Weight on Quality of Life (IWQOL) questionnaire

All patients will have Quality of life assessment with IWQOL questionnaire

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient aged between 18 and 70 years old,
* Female or male patients
* Patient eligible for one of the two situations defined below:

1. Primary bariatric or metabolic surgery, with a BMI corresponding to one of the 3 following situations, in accordance with the french National Authority for Health (HAS) recommendations published in February 2024:

* 40 kg/m² OR
* 35 kg/m² with at least one comorbidity that may improve after surgery (e.g.: high blood pressure, sleep apnea syndrome and other severe respiratory disorders, type 2 diabetes, disabling osteoarticular diseases, steatohepatitis not alcoholic, dyslipidemia, osteoarthritis) OR between 30 and 35 kg/m² with uncontrolled type 2 diabetes
2. Revision surgery for complication and/or side effects of a previous bariatric surgery
* Patient who has benefited from a pluridisciplinary evaluation (medical, surgical, psychiatric), with a favorable opinion for a bariatric.
* Patient who agrees to be included in the study and who signs the informed consent form,

Exclusion Criteria

* Presence of a severe and evolutive life threatening pathology, unrelated to obesity,
* Pregnancy or desire to be pregnant during the study,
* Patient not affiliated to a French or European healthcare insurance,
* Patient under supervision or guardianship
* Patient who is unable to give consent,
* Patient who does not understand French
* Patient who has already been included in a trial which has a conflict of interests with the present study
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Département de chirurgie digestive et endocrinienne Groupe Hospitalier Pellegrin Place Amélie Raba Léon 33076 BORDEAUX

Bordeaux, , France

Site Status RECRUITING

Département de chirurgie digestive CHRU Dijon - Hôpital Le Bocage Bd du Maréchal de Lattre de Tassigny 21000 DIJON

Dijon, , France

Site Status RECRUITING

Digestive Surgery Department CHU Grenoble BP217 - 38043 GRENOBLE Cedex 09

Grenoble, , France

Site Status RECRUITING

Service de Chirurgie Générale et Digestive Grand Hopital de l'Est Francilien Site de Marne La Vallée 2-4 Cours de la Gondoire 77600 JOSSIGNY

Jossigny, , France

Site Status RECRUITING

Service de Chirurgie Générale et Endocrinienne CHU de Lille - Hôpital Claude Huriez 1 rue Michel Polonovski 59000 LILLE

Lille, , France

Site Status RECRUITING

Hospices Civils de Lyon - Hôpital Edouard Herriot Chirurgie Digestive et Bariatrique 5 Place d'Arsonval - 69437 Lyon Cedex 03 - FRANCE

Lyon, , France

Site Status RECRUITING

Département de chirurgie digestive et bariatrique CHU de Nantes - Site Hôtel-Dieu - HME 1 Place Alexis Ricordeau 44000 NANTES

Nantes, , France

Site Status RECRUITING

Département de Chirurgie digestive Hôpital de la Source CHU d'ORLEANS 14 Avenue de l'hôpital 45100 ORLEANS LA SOURCE

Orléans, , France

Site Status RECRUITING

Service de Chirurgie Digestive Hépato-bilio-pancréatique et Transplantation Hépatique Chirurgie Bariatrique, coelioscopique et robotique AP-HP - Hôpital Universitaire La Pitié Salpêtrière 47-83 boulevard de l'hôpital 75013 PARIS

Paris, , France

Site Status RECRUITING

Département de chirurgie digestive, oncologique et bariatrique AP-HP - Hôpital Européen Georges Pompidou 20 rue Leblanc 75015 PARIS

Paris, , France

Site Status RECRUITING

Département de chirurgie digestive, œsogastrique et bariatrique AP-HP - Hôpital Bichat - Claude-Bernard 46 Rue Henri Huchard 75018 PARIS

Paris, , France

Site Status RECRUITING

Département de chirurgie viscérale CHU de Poitiers 2 Rue de la Miletrie - CS 90577 - 86000 POITIERS

Poitiers, , France

Site Status RECRUITING

Clinique Chirurgicale Mutualiste 3 rue le verrier - BP 209 42100 SAINT ETIENNE

Saint-Etienne, , France

Site Status RECRUITING

Département de chirurgie digestive et endocrinienne CHU de Strasbourg - Nouvel Hôpital civil Rez-de-chaussée 1 place de l'hôpital BP 426 67091 STRASBOURG cedex

Strasbourg, , France

Site Status RECRUITING

Service de Chirurgie Digestive Hôpital Rangueil - CHU de Toulouse 1 avenue du Pr Jean Poulhès - TSA 50032 31059 TOULOUSE Cedex 9

Toulouse, , France

Site Status RECRUITING

Département de Chirurgie Viscérale Métabolique et Cancérologique Responsable de l'Unité de Chirurgie Endocrinienne Université de Lorraine CHRU de Nancy - Hôpital Brabois adultes 11 allée du Morvan 54511 VANDOEUVRE LES NANCY

Vandœuvre-lès-Nancy, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Maud ROBERT, MD, PHD

Role: CONTACT

+33 4 72 11 62 63

Dominique DELAUNAY, MD, PHD

Role: CONTACT

+33 4 72 11 00 64

Facility Contacts

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Caroline GRONNIER, MD PhD

Role: primary

+33 5 57 65 60 05

Olivier FACY, MD PhD

Role: primary

+33 03.80.29.37.47

Fabian RECHE, MD PhD

Role: primary

+33 4 76 76 54 28

Alexandre CORTES, MD PhD

Role: primary

+33 1 61 10 71 64

Robert CAIAZZO, MD PhD

Role: primary

+33 3 20 44 55 16

Maud ROBERT, Professor

Role: primary

+33 4 72 11 62 63

Claire BLANCHARD, MD PhD

Role: primary

+33 2 40 08 33 33

Adel ABOU-MRAD FRICQUEGNON, MD PhD

Role: primary

+33 2 38 22 95 10

Adriana TORCIVIA, MD PhD

Role: primary

+33 1 42 17 56 44

Lionel REBIBO, MD PhD

Role: primary

+33 1 56 09 58 68

Tigran POGHOSYAN, MD PhD

Role: primary

+33 1 40 25 82 39

Jean-Pierre FAURE, MD PhD

Role: primary

+33 5.49.44.39.14

Pierre BLANC, MD PhD

Role: primary

+33 4 77 81 82 88

Michel VIX, MD PhD

Role: primary

+33 03 69 55 13 09

Géraud TUYERAS, MD PhD

Role: primary

+33 5 61 32 34 20

Claire NOMINE-CRIQUI, MD PhD

Role: primary

+33 3 83 15 71 43

Other Identifiers

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69HCL24_0757

Identifier Type: -

Identifier Source: org_study_id

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