Examining the Effectiveness of Multidisciplinary Care Teams in Improving Outcomes for Breast Cancer Patients

NCT ID: NCT06856876

Last Updated: 2025-03-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

73 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-01

Study Completion Date

2024-04-30

Brief Summary

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To compare clinical outcomes, patient-reported measures (PROMs), and healthcare utilization between standard care with or without an MDCT in a cohort of women treated for breast cancer.

Detailed Description

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This single-center, prospective interventional trial evaluates the effectiveness of Multidisciplinary Care Teams (MDCTs) in improving outcomes for newly diagnosed breast cancer patients at Hayatabad Medical Complex, Peshawar. The study enrolled 73 participants from May 2021 to April 2024, with follow-up sessions every six months for up to two years.

Participants were randomly assigned to two groups:

Group A (n=37): Received care through MDCTs, which included radiologists, oncologists, and surgeons collaborating to create personalized treatment plans and monitor patient progress.

Group B (n=36): Received standard therapy according to existing institutional protocols.

The study assesses multiple outcomes, including \*\*disease-free survival (DFS), overall survival (OS), recurrence rates, complication rates, patient-reported outcomes (PROs), quality of life (measured via SF-36), and healthcare utilization.

Statistical analyses include Kaplan-Meier survival curves, log-rank tests, Cox proportional hazards regression models, repeated-measures ANOVA, and linear regression models to identify predictors of survival and quality of life.

The study protocol was approved by the Institutional Review Board (IRB) and complies with the Declaration of Helsinki. All participants provided informed consent prior to enrollment.

Conditions

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Breast Cancers Breast Cancer Female Breast Cancer Stage I

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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MDCT (Group A)

Participants receive multidisciplinary care team (MDCT) treatment, including personalized treatment plans developed by oncologists, radiologists, and surgeons.

Group Type EXPERIMENTAL

Multidisciplinary Care Team (MDCT) Approach

Intervention Type OTHER

A personalized breast cancer treatment plan developed through regular case discussions by a team of radiologists, oncologists, and surgeons. The MDCT coordinates patient support services and tracks treatment progress according to evidence-based guidelines.

Standard Therapy (Group B)

Participants receive standard care for breast cancer according to the current institutional protocols.

Group Type ACTIVE_COMPARATOR

Standard Breast Cancer Therapy

Intervention Type OTHER

Breast cancer treatment provided according to the institutional protocols at Hayatabad Medical Complex, including standard surgery, chemotherapy, and/or radiotherapy as clinically indicated.

Interventions

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Multidisciplinary Care Team (MDCT) Approach

A personalized breast cancer treatment plan developed through regular case discussions by a team of radiologists, oncologists, and surgeons. The MDCT coordinates patient support services and tracks treatment progress according to evidence-based guidelines.

Intervention Type OTHER

Standard Breast Cancer Therapy

Breast cancer treatment provided according to the institutional protocols at Hayatabad Medical Complex, including standard surgery, chemotherapy, and/or radiotherapy as clinically indicated.

Intervention Type OTHER

Other Intervention Names

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MDCT Standard Therapy

Eligibility Criteria

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Inclusion Criteria

All female patients, diagnosed with breast cancer

Exclusion Criteria

Previous treatment for breast cancer, concurrent enrollment in another clinical research, and serious medical conditions that could affect study outcomes
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Yousaf Jan

OTHER_GOV

Sponsor Role lead

Responsible Party

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Yousaf Jan

Principal investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Yousaf Jan, MBBS, FCPS, FRCS, MRCS, ECFMG

Role: PRINCIPAL_INVESTIGATOR

Hayat Abad Medical Complex, Peshawar.

Locations

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Hayatabad Medical Complex

Peshawar, KPK, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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HMCKP2

Identifier Type: -

Identifier Source: org_study_id

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