Using da Vinci SP System for Patients With Cholelithiasis and Choledocholithiasis

NCT ID: NCT06852937

Last Updated: 2025-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-21

Study Completion Date

2026-12-31

Brief Summary

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A prospective, interventional, single arm study to investigate clinical feasibility of single-stage cholecystectomy and common bile duct exploration using da Vinci SP Surgical System (robotic surgery)

Detailed Description

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Cholelithiasis (gallstones) is a common disease of digestive tract in adults. It has been reported that 5-10% or 2 million of Taiwanese adults have gallstones according to National Health Insurance Administration.

Laparoscopic cholecystectomy is deemed a surgical standard of care for its safety, effectiveness, and benefits: less post-operative pain, faster recovery, shorter hospital stay, and better cosmesis. However, the advantages of da Vinci surgical system include enhanced vision, wristed instruments, and dexterity of control.

Robotic cholecystectomy by single-port SP system is associated with shorter operation time, shorter dissection time, and less post-operative pain.

Further improvement in robotic cholecystectomy with CBDE regarding cosmesis and patient satisfaction could be made by adopting da Vinci SP system which preserves enhanced vision and instrument dexterity with only one access port. So far there is no published data on robotic cholecystectomy with CBDE using da Vinci SP. Current study is set forth to evaluate technical feasibility and clinical outcome of robotic biliary surgery using da Vinci SP Surgical System for patients with complex cholelithiasis.

Conditions

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Cholelithiasis Choledocholithiasis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Operation of focus procedure with da Vinci SP Surgery System

Operation of cholecystectomy and common bile duct exploration with da Vinci SP Surgery System

Group Type EXPERIMENTAL

da Vinci SP Surgery System

Intervention Type DEVICE

da Vinci SP Surgery System

Interventions

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da Vinci SP Surgery System

da Vinci SP Surgery System

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Age 20 years or more
2. Symptomatic cholelithiasis with or without choledocholithiasis, symptomatic chronic cholecystitis with or without biliary tract injury or stricture
3. Indication of cholecystectomy with or without common bile duct exploration and deemed feasible for robotic surgery
4. Patient not feasible or have failed stone extraction or intervention for choledocholithiasis by endoscopic retrograde cholangiopancreatography for patients with choledocholithiasis could be included
5. ASA physical status classification 1-2 and adequate organ function
6. Patients willing and able to comply with study protocol requirements and follow-up
7. Patients who are taking anti-platelet or anti-coagulation medications are eligible for this trial, but the associated agents should be discontinued 5 days prior to the operation day. Patients who are taking Wafarin should be admitted two days earlier for bridging to Heparin. Other medications for underlying diseases can be taken as usual.
8. With informed consent

Exclusion Criteria

1. Severe acute cholecystitis
2. Suspected biliary tract cancer or untreated biliary tract cancer
3. BMI ≥35 or BMI \<18.5
4. Unable to tolerate robotic surgery position
5. Severe adhesion due to prior abdominopelvic surgery
6. Prior major upper abdominal surgery judged by the investigator as not feasible for robotic surgery
7. Active infectious disease
8. Severe concomitant illness that drastically shortens life expectancy or increases risk of therapeutic interventions, such as: severe heart disease (NYHA functional class III-IV) or severe lung disease (GOLD Group C-D)
9. Cannot follow trial-required procedures
10. Concomitant systemic or pelvic disease that increases the risk of surgery
11. Patients with coagulopathy
12. Emergency surgery
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Intuitive Surgical

INDUSTRY

Sponsor Role collaborator

National Taiwan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yao-Ming Wu

Role: PRINCIPAL_INVESTIGATOR

Vice Superintendent of NTUCC

Locations

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National Taiwan University Hospital

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Weichieh Tsai

Role: CONTACT

Phone: 886-978226836

Email: [email protected]

Jacqueline Liang

Role: CONTACT

Phone: 886-914255380

Email: [email protected]

Facility Contacts

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Yao-Ming Wu Professor, Department of Surgery, NTUH

Role: primary

Other Identifiers

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202409006DIPD

Identifier Type: -

Identifier Source: org_study_id