A Study to Assess the Relative Bioavailability of Oral ABBV-932 in Healthy Adult Participants

NCT ID: NCT06849791

Last Updated: 2026-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE1

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-26

Study Completion Date

2026-04-30

Brief Summary

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This study will assess the relative bioavailability and effect of food on pharmacokinetics of ABBV-932 oral administration in healthy adult participants.

Detailed Description

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Conditions

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Healthy Volunteer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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ABBV-932: Arm A

Participants will receive a single dose of ABBV-932 Arm A on day 1 under fasting conditions.

Group Type EXPERIMENTAL

ABBV-932

Intervention Type DRUG

Oral Capsule

ABBV-932: Arm B

Participants will receive a single dose of ABBV-932 Arm B on day 1 under fasting conditions.

Group Type EXPERIMENTAL

ABBV-932

Intervention Type DRUG

Oral tablet

ABBV-932: Arm C

Participants will receive a single dose of ABBV-932 Arm C on day 1 under fasting conditions.

Group Type EXPERIMENTAL

ABBV-932

Intervention Type DRUG

Oral Capsule

ABBV-932: Arm D

Participants will receive a single dose of ABBV-932 Arm D on day 1 with a high-fat meal.

Group Type EXPERIMENTAL

ABBV-932

Intervention Type DRUG

Oral tablet

ABBV-932: Arm E

Participants will receive a single dose of ABBV-932 Arm E on day 1 with a high-fat meal.

Group Type EXPERIMENTAL

ABBV-932

Intervention Type DRUG

Oral Capsule

ABBV-932: Arm F

Participants will receive a single dose of ABBV-932 Arm F on day 1 under fasting conditions.

Group Type EXPERIMENTAL

ABBV-932

Intervention Type DRUG

Oral Capsule

ABBV-932: Arm G

Participants will receive a single dose of ABBV-932 Arm G on day 1 with a high-fat meal.

Group Type EXPERIMENTAL

ABBV-932

Intervention Type DRUG

Oral Capsule

ABBV-932: Arm H

Participants will receive a single dose of ABBV-932 Arm H on day 1 under fasting conditions.

Group Type EXPERIMENTAL

ABBV-932

Intervention Type DRUG

Oral Capsule

Interventions

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ABBV-932

Oral Capsule

Intervention Type DRUG

ABBV-932

Oral tablet

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Body Mass Index (BMI) ≥ 18.0 to ≤ 32.0 kg/m\^2 after rounding to the tenths decimal at the time of screening and upon initial confinement. BMI is calculated as weight in kg divided by the square of height measured in meters.
* A condition of general good health, based upon the results of a medical history, physical examination, vital signs, laboratory profile, and a 12-lead ECG

Exclusion Criteria

* History of epilepsy, any clinically significant cardiac, respiratory (except mild asthma as a child), renal, hepatic, gastrointestinal, hematologic or psychiatric disease or disorder, or any uncontrolled medical illness.
* History of any clinically significant sensitivity or allergy to any medication or food.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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AbbVie

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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ABBVIE INC.

Role: STUDY_DIRECTOR

AbbVie

Locations

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Acpru /Id# 266649

Grayslake, Illinois, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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ABBVIE CALL CENTER

Role: CONTACT

844-663-3742

Related Links

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Other Identifiers

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M24-889

Identifier Type: -

Identifier Source: org_study_id

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