Efficacy of Platelet-Rich Plasma Injection in Dry Eye Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-17

Study Completion Date

2026-07-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigatror wants to show the efficacy of Platelet-Rich Plasma injection in lacrimal gland to restore the lacrimal secretion in patients presenting aqueous deficiency reponsible for severe dry eye syndrome.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye

NCT02257957

Dry Eye Sjogren Syndrome

COMPLETED PHASE3

Study of Platelet Rich Plasma Drops to Moderate Clinically Significant Dry Eye

NCT05121493

Dry Eye Syndromes

NOT_YET_RECRUITING NA

Comparison of Efficacy Between 100% Platelet-rich Plasma and 100% Serum Eye Drops in Dry Eye Disease

NCT04683796

Dry Eye Disease

COMPLETED PHASE3

Platelet Rich Plasma Eye Drops for Treatment of Ocular Surface Disease

NCT04608084

Ocular Surface Disease Dry Eye Syndromes

UNKNOWN PHASE4

Lacripep™ in Subjects With Dry Eye Associated With Primary Sjögren's Syndrome

NCT03226444

Primary Sjögren Syndrome Dry Eye

COMPLETED PHASE1/PHASE2

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

injections in lacrimal gland four times during the study for each patient

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Severe Dry Eye Syndromes Dry Eye Syndromes

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

To assess the lacrimal secretion after 4 injections of PRP in lacrimal gland

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Injection of Platelet-Rich Plasma (PRP)

Group Type EXPERIMENTAL

injections of Platelet-Rich Plasma in lacrimal gland

Intervention Type OTHER

injections of Platelet-Rich Plasma in lacrimal gland

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

injections of Platelet-Rich Plasma in lacrimal gland

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Platelet counts, and clotting factors in the standarts
* Presenting with severe dry keratoconjunctivitis diagnosed by an ophthalmologist

Exclusion Criteria

* Patients with significant fibrosis of the conjunctival portion of the lacrimal gland
* Patients with complete stenosis of both lacrimal meatus in the treated eye

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No