Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
2000 participants
OBSERVATIONAL
2025-03-06
2026-12-31
Brief Summary
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Participants will complete one visit where they will undergo an aquagenic wrinkling procedure to see how their hands respond.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Potential Cystic Fibrosis Carriers
Participants that are identified as potential cystic fibrosis carriers based on aquagenic wrinkling results.
Aquagenic Wrinkling
Participants will be asked to remove all jewelry from the hand(s) and wrist(s) that will be undergoing the aquagenic wrinkling procedures. Photographs will be taken of the palmar surface of the hand(s). The participant will submerge the hand(s) undergoing testing in a water bath for one minute. After one minute, they will remove their hand(s), dry them gently with a towel, and photographs will be taken of the palmar surface of the hand(s). The participant will re-submerge their hand(s) in the appropriate conditions for another minute and the process will be repeated 20 times for 20 total minutes submerged in the water.
Potential Controls
Participants that are identified as potential controls based on aquagenic wrinkling results.
Aquagenic Wrinkling
Participants will be asked to remove all jewelry from the hand(s) and wrist(s) that will be undergoing the aquagenic wrinkling procedures. Photographs will be taken of the palmar surface of the hand(s). The participant will submerge the hand(s) undergoing testing in a water bath for one minute. After one minute, they will remove their hand(s), dry them gently with a towel, and photographs will be taken of the palmar surface of the hand(s). The participant will re-submerge their hand(s) in the appropriate conditions for another minute and the process will be repeated 20 times for 20 total minutes submerged in the water.
Interventions
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Aquagenic Wrinkling
Participants will be asked to remove all jewelry from the hand(s) and wrist(s) that will be undergoing the aquagenic wrinkling procedures. Photographs will be taken of the palmar surface of the hand(s). The participant will submerge the hand(s) undergoing testing in a water bath for one minute. After one minute, they will remove their hand(s), dry them gently with a towel, and photographs will be taken of the palmar surface of the hand(s). The participant will re-submerge their hand(s) in the appropriate conditions for another minute and the process will be repeated 20 times for 20 total minutes submerged in the water.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Unable to speak English
* Unable to provide written informed consent
* Prisoner status
* An open wound on either hand
* A tattoo on either hand
* Missing any portion of either hand
* Diagnosis of Diabetes
* Diagnosis of Hyperhidrosis
* Diagnosis of Raynaud's Disease
* Diagnosis of Atopic Dermatitis
* Regularly taking ACE inhibitors or angiotensin receptor blockers
18 Years
24 Years
ALL
Yes
Sponsors
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University of Iowa
OTHER
Responsible Party
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Philip Polgreen
Professor
Principal Investigators
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Philip M Polgreen, MD
Role: PRINCIPAL_INVESTIGATOR
University of Iowa
Locations
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University of Iowa
Iowa City, Iowa, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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202410028
Identifier Type: -
Identifier Source: org_study_id
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