Agreement and Precision Study of UNITY® DX and a Comparator Biometer

NCT ID: NCT06826599

Last Updated: 2025-08-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-18

Study Completion Date

2025-03-30

Brief Summary

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The purpose of this study is to validate the clinical measurement performance of an investigational biometer. Subjects will undergo multiple measurements of the eye, and the agreement, repeatability, and reproducibility of the biometric measurements will be evaluated.

Detailed Description

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This is intended to be a 1-visit study approximately 3 hours in length with planned duration of exposure of up to 20 minutes per device (investigational biometer and IOLMaster 700). Four cohorts will be enrolled. One eye per subject will be assessed.

Conditions

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Normal Eyes Abnormal Eyes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1 - Normal Eyes

The eye will be imaged up to seven times with the biometer to achieve three acceptable scans

Investigational Biometer

Intervention Type DEVICE

Investigational non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and measurement of anterior segment and biometric parameters

IOLMaster 700 Biometer

Intervention Type DEVICE

Commercially available non-contact instrument used to capture optical biometry measurements

Group 2 - Eyes with cataracts

The eye will be imaged up to seven times with the biometer to achieve three acceptable scans

Investigational Biometer

Intervention Type DEVICE

Investigational non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and measurement of anterior segment and biometric parameters

IOLMaster 700 Biometer

Intervention Type DEVICE

Commercially available non-contact instrument used to capture optical biometry measurements

Group 3 - Eyes with significant refractive errors

The eye will be imaged up to seven times with the biometer to achieve three acceptable scans

Investigational Biometer

Intervention Type DEVICE

Investigational non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and measurement of anterior segment and biometric parameters

IOLMaster 700 Biometer

Intervention Type DEVICE

Commercially available non-contact instrument used to capture optical biometry measurements

Group 4 - Eyes with abnormal corneal topography

The eye will be imaged up to seven times with the biometer to achieve three acceptable scans

Investigational Biometer

Intervention Type DEVICE

Investigational non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and measurement of anterior segment and biometric parameters

IOLMaster 700 Biometer

Intervention Type DEVICE

Commercially available non-contact instrument used to capture optical biometry measurements

Interventions

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Investigational Biometer

Investigational non-contact, non-invasive ophthalmic imaging and analysis device used for visualization of ocular structures and measurement of anterior segment and biometric parameters

Intervention Type DEVICE

IOLMaster 700 Biometer

Commercially available non-contact instrument used to capture optical biometry measurements

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Able to understand and sign an Institution Review Board approved Informed Consent form.
* Willing and able to attend all scheduled study visits as required by the protocol.
* Identified by the investigator as eligible for at least one of the 4 eye groups identified in the protocol.

Exclusion Criteria

* Unable to fixate, for example, due to nystagmus or other eye movement abnormality.
* Any ocular disease and/or condition that, in the investigator's clinical judgment, may put the subject at significant risk, may compromise study results, or may interfere significantly with the subject's participation in the study.
* Active ocular infection or inflammation.
* Rigid or contact lens wear during the previous two weeks prior to Screening.
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cylite Pty Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Arnold Ouyang, PhD

Role: STUDY_DIRECTOR

Cylite Pty Ltd

Locations

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NorthEast Eye Research Associates LLC

Woburn, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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CYC-CL-SOP-004

Identifier Type: -

Identifier Source: org_study_id

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