A Study to Learn About How the Flu and COVID-19 Vaccines Act in Healthy People
NCT ID: NCT06821061
Last Updated: 2025-12-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
PHASE1/PHASE2
2645 participants
INTERVENTIONAL
2025-02-10
2025-12-22
Brief Summary
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This study is seeking healthy participants aged 18 or older. All participants in this study will receive only 1 shot to their arm, either a flu or COVID vaccine, alone or mixed. Participants will take part in this study for about 6 months, and participants will need to visit the clinical study site at least 4 times.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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Arm OO
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 5)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm PP
Medium Dose Investigational Influenza Vaccine (1)
Investigational Influenza Vaccine
Investigational Influenza Vaccine
Arm QQ
High Dose Investigational Influenza Vaccine (2)
Investigational Influenza Vaccine
Investigational Influenza Vaccine
Arm RR
Licensed COVID-19 Vaccine
Licensed COVID-19 Vaccine
Pfizer-BioNTech COVID-19 Vaccine
Arm SS
Licensed Influenza Vaccine (3)
Licensed Influenza Vaccine 3
Licensed Influenza Vaccine 3
Arm A
Low Dose COVID-19 Vaccine (1a)
Investigational COVID-19 Vaccine
Investigational COVID-19 Vaccine
Arm B
Low Dose COVID-19 Vaccine ( 1b)
Investigational COVID-19 Vaccine
Investigational COVID-19 Vaccine
Arm C
Low Dose COVID-19 Vaccine ( 1c)
Investigational COVID-19 Vaccine
Investigational COVID-19 Vaccine
Arm D
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 1)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm E
Investigational Influenza and COVID-19 Combination Vaccine (Medium Dose Combination 2)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm F
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 3)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm G
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 4)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm H
Licensed COVID-19 Vaccine
Licensed COVID-19 Vaccine
Pfizer-BioNTech COVID-19 Vaccine
Arm I
Licensed Influenza Vaccine (1)
Licensed Influenza Vaccine 1
Licensed Influenza Vaccine 1
Arm J
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 5)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm K
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 6)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm L
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 7)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm M
Licensed COVID-19 Vaccine
Licensed COVID-19 Vaccine
Pfizer-BioNTech COVID-19 Vaccine
Arm N
Licensed Influenza Vaccine (2)
Licensed Influenza Vaccine 2
Licensed Influenza Vaccine 2
Arm AA
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 6)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm BB
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 4)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm CC
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 7)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm DD
Investigational Influenza and COVID-19 Combination Vaccine (Medium Dose Combination 2)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm EE
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 3)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm FF
Licensed COVID-19 Vaccine
Licensed COVID-19 Vaccine
Pfizer-BioNTech COVID-19 Vaccine
Arm GG
Licensed Influenza Vaccine (3)
Licensed Influenza Vaccine 3
Licensed Influenza Vaccine 3
Arm HH
Licensed Influenza Vaccine (2)
Licensed Influenza Vaccine 2
Licensed Influenza Vaccine 2
Arm II
Low Dose COVID-19 Vaccine ( 1b)
Investigational COVID-19 Vaccine
Investigational COVID-19 Vaccine
Arm JJ
Low Dose COVID-19 Vaccine ( 1c)
Investigational COVID-19 Vaccine
Investigational COVID-19 Vaccine
Arm KK
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 4)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm LL
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 7)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm MM
Investigational Influenza and COVID-19 Combination Vaccine (Medium Dose Combination 2)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Arm NN
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 3)
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Interventions
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Investigational Influenza Vaccine
Investigational Influenza Vaccine
Investigational COVID-19 Vaccine
Investigational COVID-19 Vaccine
Investigational Influenza and COVID-19 Combination Vaccine
Investigational Combined Influenza and COVID-19 Vaccine
Licensed Influenza Vaccine 1
Licensed Influenza Vaccine 1
Licensed Influenza Vaccine 2
Licensed Influenza Vaccine 2
Licensed Influenza Vaccine 3
Licensed Influenza Vaccine 3
Licensed COVID-19 Vaccine
Pfizer-BioNTech COVID-19 Vaccine
Eligibility Criteria
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Inclusion Criteria
* Healthy participants who are determined by medical history, physical examination (if clinically required), and clinical judgement of the investigator to be eligible for inclusion in the study
Exclusion Criteria
* Vaccination with any investigational or licensed COVID 19 vaccine within 150 days of enrollment.
* Receipt of antiviral therapies for influenza (eg, Tamiflu) within 180 days prior to Day 1.
Refer to the study contact for further eligibility details
18 Years
ALL
Yes
Sponsors
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Pfizer
INDUSTRY
BioNTech SE
INDUSTRY
Responsible Party
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Principal Investigators
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Pfizer CT.gov Call Center
Role: STUDY_DIRECTOR
Pfizer
Locations
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Anaheim Clinical Trials, LLC
Anaheim, California, United States
Orange County Research Center
Lake Forest, California, United States
Artemis Institute for Clinical Research
Riverside, California, United States
Artemis Institute for Clinical Research
San Diego, California, United States
Diablo Clinical Research, Inc.
Walnut Creek, California, United States
Clinical Research Consulting
Milford, Connecticut, United States
Alliance for Multispecialty Research, LLC
Doral, Florida, United States
Indago Research & Health Center, Inc
Hialeah, Florida, United States
Miami Dade Medical Research Institute, LLC
Miami, Florida, United States
Palm Springs Community Health Center
Miami Lakes, Florida, United States
Clinical Research Atlanta
Stockbridge, Georgia, United States
East-West Medical Research Institute
Honolulu, Hawaii, United States
Clinical Research Professionals
Chesterfield, Missouri, United States
Las Vegas Clinical Trials
North Las Vegas, Nevada, United States
Upstate Global Health Institute
East Syracuse, New York, United States
University of Rochester Medical Center
Rochester, New York, United States
Trial Management Associates - Wilmington - Floral Parkway
Wilmington, North Carolina, United States
Centricity Research Columbus Ohio Multispecialty
Columbus, Ohio, United States
DM Clinical Research - Philadelphia
Philadelphia, Pennsylvania, United States
Coastal Carolina Research Center
North Charleston, South Carolina, United States
AMR Clinical
Knoxville, Tennessee, United States
AMR Clinical
Knoxville, Tennessee, United States
Clinical Research Associates Inc
Nashville, Tennessee, United States
Headlands Horizons, LLC dba Headlands Research-Brownsville
Brownsville, Texas, United States
DM Clinical Research- Cyfair
Houston, Texas, United States
SMS Clinical Research
Mesquite, Texas, United States
Dynamed Clinical Research, LP d/b/a DM Clinical Research
Tomball, Texas, United States
J. Lewis Research, Inc. / Foothill Family Clinic
Salt Lake City, Utah, United States
J. Lewis Research, Inc. / Foothill Family Clinic South
Salt Lake City, Utah, United States
Charlottesville Medical Research
Charlottesville, Virginia, United States
Kaiser Permanente Washington Health Research Institute (KPWHRI)
Seattle, Washington, United States
Countries
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Related Links
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To obtain contact information for a study center near you, click here.
Other Identifiers
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C6271001
Identifier Type: -
Identifier Source: org_study_id