Respiatory Viral Infections in Patients with Multiple Myeloma

NCT ID: NCT06810115

Last Updated: 2025-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

219 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-10-01

Study Completion Date

2024-10-01

Brief Summary

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Respiratory viruses are known to be a major cause of morbodity in multiple myeloma patients but prospective long-term sudies are lacking. We analysed 219 multiple myeloma patients that had 554 nasopharingeal swabs with 58 documented viral episodes. Respiratory viruses studied were rhinovirus, enterovirus, parainflienza, respirator, syncytial virus, metapneumovirus, coronavirus, bocavirus, influenza A, influenza B. Clinical data were extracted from a prospectively entered database, medical records were reviewed. We have prospectively studiend patients until May 2019 when we gathered survival data. Lastly because of Covid-19 pandemic when almost no other viral infections were isolated, we analysed clinical course of respiratory infections in patients with multiple myeloma after the pandemic.

Detailed Description

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Conditions

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Multiple Mieloma Respiratory Viral Infections

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patient with multiple myeloma

Viral PCR test

Intervention Type OTHER

Viral PCR test regardles of symptoms

Interventions

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Viral PCR test

Viral PCR test regardles of symptoms

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with multiple myeloma

Exclusion Criteria

\-
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Medical Centre Ljubljana

OTHER

Sponsor Role lead

Responsible Party

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Polona Novak

Polona Novak, MD

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Blimark C, Holmberg E, Mellqvist UH, Landgren O, Bjorkholm M, Hultcrantz M, Kjellander C, Turesson I, Kristinsson SY. Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients. Haematologica. 2015 Jan;100(1):107-13. doi: 10.3324/haematol.2014.107714. Epub 2014 Oct 24.

Reference Type BACKGROUND
PMID: 25344526 (View on PubMed)

Other Identifiers

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83/03/15

Identifier Type: -

Identifier Source: org_study_id

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