Prediction of Tongue Base Obstruction During Sleep

NCT ID: NCT06792045

Last Updated: 2025-03-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

48 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-04-30

Study Completion Date

2026-09-30

Brief Summary

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This study investigates the hypothesis that, in children, tongue motor functions can predict both the anatomical site and the degree of upper airway obstruction contributing to obstructive sleep-disordered breathing.

Detailed Description

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Patients will be enrolled during their visit to the ENT physician. Subsequently, their tongue motor functions will be assessed during their pre-surgical appointment. Finally, they will undergo a drug-induced sleep endoscopy prior to their surgery.

Conditions

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Obstructive Sleep Disordered Breathing

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Children with obstructive sleep disordered breathing

Physiotherapist assessment

Intervention Type OTHER

* Tongue motor skills (Tongue pressures and tongue mobility, assessed through the Iowa Oral Performance Instrument and the Motricité Bucco-Linguo-Faciale tongue subscore, respectively)
* Tongue restriction of mobility due to its frenulum (assessed through the Quick Tongue-Tie assessment tool)
* Breathing Pattern (questionnaire from Abreu RR, Rocha RL, Lamounier JA, Guerra AF. Etiology, clinical manifestations and concurrent findings in mouth-breathing children. J Pediatr (Rio J). 2008;84(6):529-535.).

ENT assessment

Intervention Type OTHER

Data from the ENT appointment will be collected (e.g., sex, height, weight)

Drug-Induced Sleep Endoscopy

Intervention Type DIAGNOSTIC_TEST

A Drug-Induced Sleep Endoscopy will be performed, recorded, and evaluated by two blinded raters using the IPSES scale.

Interventions

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Physiotherapist assessment

* Tongue motor skills (Tongue pressures and tongue mobility, assessed through the Iowa Oral Performance Instrument and the Motricité Bucco-Linguo-Faciale tongue subscore, respectively)
* Tongue restriction of mobility due to its frenulum (assessed through the Quick Tongue-Tie assessment tool)
* Breathing Pattern (questionnaire from Abreu RR, Rocha RL, Lamounier JA, Guerra AF. Etiology, clinical manifestations and concurrent findings in mouth-breathing children. J Pediatr (Rio J). 2008;84(6):529-535.).

Intervention Type OTHER

ENT assessment

Data from the ENT appointment will be collected (e.g., sex, height, weight)

Intervention Type OTHER

Drug-Induced Sleep Endoscopy

A Drug-Induced Sleep Endoscopy will be performed, recorded, and evaluated by two blinded raters using the IPSES scale.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age between 6 and 17 years old
* Medical diagnosis of obstructive sleep-disordered breathing requiring surgical removal of tonsils (partial or total) and/or adenoids
* Positive Pediatric Sleep Questionnaire (8 or more positive responses)
* Eligibility for surgical intervention

Exclusion Criteria

* Neurological, cardiac, or respiratory comorbidity other than obstructive sleep-disordered breathing
* Previous surgery of the upper airway or oral cavity
* History of or current head or neck cancer
* Cranial, upper airway, or oral cavity malformation
* Contraindication to performing endoscopy
Minimum Eligible Age

6 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Université Catholique de Louvain

OTHER

Sponsor Role lead

Responsible Party

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William Poncin

Principal Investigator, Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cliniques universitaires Saint-Luc

Brussels, , Belgium

Site Status

Countries

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Belgium

Central Contacts

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William Poncin, Pr, Dr.

Role: CONTACT

+32470592032

Pierre Cnockaert, PT

Role: CONTACT

Facility Contacts

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William Poncin, Pr., Dr.

Role: primary

+32470592032

Other Identifiers

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PTOS

Identifier Type: -

Identifier Source: org_study_id

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