Evaluation of Efficacy and Safety Parameters of Different Antibiotics Regimens for Management of Empyema

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-01

Study Completion Date

2025-05-01

Brief Summary

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To evaluate the impact of using different antibiotic regimens including single and combined agents as the empirical therapy and evaluate the clinical outcomes regarding safety, efficacy, and pharmacodynamics parameters.

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Detailed Description

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Conditions

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Empyema, Pleural

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Patient with empyema

Tavanic (levofloxacin )and dalacin (clindamycin)

Group Type OTHER

Levofloxacin + cefipime

Intervention Type DRUG

Group 2

Empyema patient

Tavanic (levofloxacin) and cefipime

Group Type OTHER

Levofloxacin + clindamycin

Intervention Type DRUG

Group 1

patient has lung empyema

Moxiflox (moxifloxacin) and meronem

Group Type OTHER

Moxifloxacin + meronam

Intervention Type DRUG

Group 3

Interventions

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Levofloxacin + clindamycin

Group 1

Intervention Type DRUG

Levofloxacin + cefipime

Group 2

Intervention Type DRUG

Moxifloxacin + meronam

Group 3

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Confirmed Diagnosis of Empyema: Patients with a clinical and radiological diagnosis of

Exclusion Criteria

1 - Hypersensitivity or Allergy to the selected antibiotic: Patients with a known history of hypersensitivity or allergic reactions to used antibiotics.

2- Pregnancy and Lactation

Eligible Sex

ALL

Accepts Healthy Volunteers

No