Study on Plasmablastic Lymphoma Patients

NCT ID: NCT06781359

Last Updated: 2025-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-02-14

Study Completion Date

2028-02-01

Brief Summary

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This is an observational, multicenter, international and retrospective study, that aims to collect data on clinical and pathological characteristics, treatment regimens, outcome, and prognostic factors (clinical, biomarkers and/or radio-metabolic) in patients affected by PBL.

Detailed Description

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This study is an International, multicenter, observational, retrospective trial on patients affected by PBL. The information collected aim to obtain data from the real-life diagnosis, staging, management and treatment and outcome of PBL patients. A centralized pathological review of pathological samples is planned to define the rate of accurate diagnosis and to define a recommended immunohistochemical diagnostic panel for PBL. In addition, exploratory analysis will be performed to better characterize PBL.

Conditions

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Plasmablastic Lymphoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Plasmablastic lymphoma patients

Patients with diagnosis (histologically confirmed) of plasmablastic lymphoma (PBL) between Jan 1st 2000 and Dec 31st 2022

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of plasmablastic lymphoma (PBL) between Jan 1st 2000, and Dec 31st 2022
* Histologically confirmed plasmablastic lymphoma (PBL) diagnosis according to local pathological report
* Age \> 18 years old
* Availability of complete medical records
* Availability of histopathological material requested by the study

Exclusion Criteria

* Any other histology than PBL
* Lack of complete medical records
* Lack of histopathological material requested by the study
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AIL Roma - Italia

UNKNOWN

Sponsor Role collaborator

AIL Cuneo - Italia

UNKNOWN

Sponsor Role collaborator

Fondazione Italiana Linfomi - ETS

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alessia Castellino, MD

Role: PRINCIPAL_INVESTIGATOR

UO Ematologia, AO Santa Croce e Carle, Cuneo - Italy

Emanuele Ravano, MD

Role: PRINCIPAL_INVESTIGATOR

UO Ematologia, Niguarda Grande Ospedale Metropolitano, Milano - Italy.

Locations

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IRCCS Centro di Riferimento Oncologico di Aviano, Divisione di Oncologia e dei Tumori immuno-correlati

Aviano, PN, Italy

Site Status RECRUITING

Ospedale C.e G. Mazzoni, U.O.C. di Ematologia

Ascoli Piceno, , Italy

Site Status RECRUITING

ASST Spedali Civili di Brescia, Ematologia

Brescia, , Italy

Site Status NOT_YET_RECRUITING

A.O. S. Croce e Carle, S.C. di Ematologia e Trapianto di Midollo Osseo

Cuneo, , Italy

Site Status RECRUITING

Azienda Ospedaliera Universitaria Careggi, Unità funzionale di Ematologia

Florence, , Italy

Site Status RECRUITING

ASST -Fatebenefratelli - Polo Luigi Sacco Oncologia

Milan, , Italy

Site Status NOT_YET_RECRUITING

ASST Grande Ospedale Metropolitano Niguarda, SC Ematologia

Milan, , Italy

Site Status RECRUITING

Istituto Scientifico San Raffaele, Unità Linfomi - Dipartimento Oncoematologia

Milan, , Italy

Site Status RECRUITING

Ospedale Maggiore Policlinico - Fondazione IRCCS Ca' Granda, Ematologia

Milan, , Italy

Site Status NOT_YET_RECRUITING

Fondazione IRCCS San Gerardo dei Tintori, Ematologia

Monza, , Italy

Site Status RECRUITING

AOU Maggiore della Caritа di Novara, SCDU Ematologia

Novara, , Italy

Site Status RECRUITING

Azienda Ospedaliera Universitaria di Padova, Ematologia

Padua, , Italy

Site Status NOT_YET_RECRUITING

Presidio ospedaliero A. Tortora, U.O. Onco-ematologia

Pagani, , Italy

Site Status NOT_YET_RECRUITING

Azienda Unitа Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova, Ematologia

Reggio Emilia, , Italy

Site Status RECRUITING

Azienda Ospedaliera Universitaria Sant' Andrea, Ematologia

Roma, , Italy

Site Status RECRUITING

Policlinico Umberto I - Università La Sapienza, Istituto Ematologia, Dipartimento di Medicina Traslazionale e di Precisione

Roma, , Italy

Site Status RECRUITING

Universitа Cattolica S. Cuore, Ematologia

Roma, , Italy

Site Status NOT_YET_RECRUITING

Azienda Ospedaliero Universitaria Senese, U.O.C. Ematologia

Siena, , Italy

Site Status NOT_YET_RECRUITING

A.O.U. Città della Salute e della Scienza di Torino, Ematologia Universitaria

Torino, , Italy

Site Status NOT_YET_RECRUITING

A.O.U. Città della Salute e della Scienza di Torino, S.C. Ematologia

Torino, , Italy

Site Status NOT_YET_RECRUITING

Ospedale S. Chiara, S.S. di Ematologia

Trento, , Italy

Site Status RECRUITING

ULSS2 Marca Trevigiana, Ospedale Ca' Foncello, S.C di Ematologia

Treviso, , Italy

Site Status NOT_YET_RECRUITING

ULSS 8 Berica - Ospedale S. Bortolo, Ematologia

Vicenza, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Uffici Studi FIL

Role: CONTACT

+390131033153

Uffici Studi FIL

Role: CONTACT

+390131033160

Facility Contacts

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Michele Spina, MD

Role: primary

Piero Galieni, MD

Role: primary

Alessandro Re, MD

Role: primary

Claudia Castellino, MD

Role: primary

Luca Nassi, MD

Role: primary

Nicla La Verde, MD

Role: primary

Emanuele Ravano, MD

Role: primary

Andrés JM Ferreri, Prof

Role: primary

Francesca Gaia Rossi, MD

Role: primary

Luisa Verga, MD

Role: primary

Riccardo Bruna, MD

Role: primary

Greta Scapinello, MD

Role: primary

Catello Califano, MD

Role: primary

Angela Ferrari, MD

Role: primary

Agostino Tafuri, Prof

Role: primary

Alice Di Rocco, MD

Role: primary

Stefan Hohaus, Prof

Role: primary

Emanuele Cencini, MD

Role: primary

Federica Cavallo, MD

Role: primary

Barbara Botto, MD

Role: primary

Chandrakala Toldo, MD

Role: primary

Piero Maria Stefani, MD

Role: primary

Marcello Riva, MD

Role: primary

Other Identifiers

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FIL_PlaLy

Identifier Type: -

Identifier Source: org_study_id

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