Validation of in Vitro Method for Anti-MCPyV Immunotherapy on Patients With Cutaneous Merkel Cell Carcinoma

NCT ID: NCT06780475

Last Updated: 2025-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

15 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-27

Study Completion Date

2027-05-31

Brief Summary

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The aim of the study is to test and validate in vitro a cell therapy approach for MCPyV+ Merkel Cell Carcinoma patients.

Detailed Description

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The aim of the study is to test and validate in vitro a cell therapy approach for MCPyV+ Merkel Cell Carcinoma patients.

Conditions

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Merkel Cell Carcinoma of Skin

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients \>= 18 years old;
* Diagnosed with Merkel cell carcinoma of skin, ongoing for local treatment, systemic treatment, complementary treatment or an active follow-up;
* Informed for the study and no-opposed for participation;
* Affiliated with a social security scheme or in an equivalent situation.

Exclusion Criteria

* Patients ongoing another interventional clinical trial;
* Patients under guardianship or trusteeship;
* Pregnancy or breastfeed;
* Patients refusal.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

Sponsor Role collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Astrid Blom, MD

Role: PRINCIPAL_INVESTIGATOR

Dermato-oncology Department, Ambroise Paré Hospital, APHP

Yassine Taoufik, MD, PhD

Role: STUDY_DIRECTOR

U1186 INSERM, PAUL BROUSSE Hospital, APHP

Locations

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Dermato-oncology Department, Ambroise Paré Hospital, APHP

Boulogne-Billancourt, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Astrid Blom, MD

Role: CONTACT

+33 (01) 49 09 44 82

Yassine Taoufik, MD, PhD

Role: CONTACT

Other Identifiers

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2024-A00643-44

Identifier Type: REGISTRY

Identifier Source: secondary_id

APHP240470

Identifier Type: -

Identifier Source: org_study_id

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