A Clinical Study to Evaluate the Efficacy, Tolerability, and Safety of Bempedoic Acid

NCT ID: NCT06780410

Last Updated: 2025-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE3

Total Enrollment

240 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-20

Study Completion Date

2025-10-31

Brief Summary

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This trial is a phase III study to evaluate the efficacy , tolerability, and safety of Bempedoic Acid Tablets in patients with hyperlipidemia not adequately controlled by Statins.

Detailed Description

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Conditions

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Primary Hyperlipidemia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Bempedoic acid

Once daily

Group Type EXPERIMENTAL

Bempedoic Acid Tablet

Intervention Type DRUG

Once daily, oral

Placebo

Once daily

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Once daily, oral

Interventions

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Bempedoic Acid Tablet

Once daily, oral

Intervention Type DRUG

Placebo

Once daily, oral

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 1\. 18 years and older, male or female.
* 2\. 18 kg/m2 ≤Body Mass Index (BMI) ≤35 kg/m2.
* 3\. Participants must agree to use reliable contraception from the screening day until 30 days after the last dose, and must not donate sperm or eggs for assisted reproduction purposes.
* 4\. Fully understand the purpose and requirements of the study, voluntarily participate in the clinical trial, and sign a written informed consent form, capable of completing the entire study process.

Exclusion Criteria

* 1\. Known allergy to any component of the investigational drug or its excipients, or a history of allergic diseases (e.g., asthma, urticaria, eczema) or allergic constitution.
* 2\. Fasting triglycerides (TG) ≥ 5.64 mmol/L (≥ 500 mg/dL) at screening.
* 3\. History of malignant tumors prior to screening.
* 4\. History of drug, alcohol, amphetamines, or other drug abuse.
* 5\. Participation in other clinical studies and use of other investigational drugs or medical devices within 3 months prior to screening or within 5 half-lives of the drugs (whichever is longer).
* 6\. Pregnant or breastfeeding females, or those with a positive human chorionic gonadotropin (HCG) pregnancy test.
* 7\. Any other factors that the investigator believes makes the participant unsuitable for the study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Gan & Lee Pharmaceuticals.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Site 01

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Wei Zhao

Role: CONTACT

010-56456726

Facility Contacts

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Wei Zhao

Role: primary

010-56456726

Other Identifiers

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BDP-HLD-301

Identifier Type: -

Identifier Source: org_study_id

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