Comparison of Thoracolumbar Interfascial Plane Block (TLIP-block) and Local Anesthetic (LA) Infiltration in Minimally Invasive Spine Surgery: A Randomized Controlled Trial
NCT ID: NCT06761079
Last Updated: 2025-01-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2024-01-16
2024-12-25
Brief Summary
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The primary outcome was total morphine consumption. Secondary outcomes included pain scores using the the numerical verbal scale (NRS), opioid-related side effects, time of the first request for rescue analgesia, time to ambulation and hospital length of stay.
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Detailed Description
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All 40 enrolled patients were randomized to receive the assigned intervention, Thoracolumbar interfascial plane group (TLIP group) and local anesthetic (LA) infiltration group (LA group).
* For TLIP group, patients will receive ultrasound-guild bilateral TLIP block with a total of 40 ml of 0.25% Bupivacaine.
* For LA group, patients will receive local anesthetic infiltration with a same drug by orthopedic surgeon.
At the end of surgery, patients were extubated and transferred to the PACU before being shifted to the orthopedic ward.
Postoperative assessments began upon admission to the PACU, designated as time zero, and continued at regular intervals in the orthopedic ward (6-, 8-, 12- and 24-hours post-surgery).
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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LA Group
Local anesthetic infiltration (0.25%marcaine 40 ml)
Local anesthetic infiltration
0.25%bupivacaine infiltration at surgical wound site by orthopedic surgeon
TLIP Group
Thoracolumbar interfascial plane block with 0.25%marcaine 40 ml under USG
Thoracolumbar interfascial plane block
Ultrasound-guild bilateral Thoracolumbar interfascial plane block with a total 40 ml, 0.25% bupivacaine by anesthesiologist
Interventions
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Thoracolumbar interfascial plane block
Ultrasound-guild bilateral Thoracolumbar interfascial plane block with a total 40 ml, 0.25% bupivacaine by anesthesiologist
Local anesthetic infiltration
0.25%bupivacaine infiltration at surgical wound site by orthopedic surgeon
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiologists classes I-III
* Able to use a patient-controlled analgesia (PCA) device
* Able to rate their pain using a numerical verbal scale (NRS)
Exclusion Criteria
* Uncooperative or unable to complete study assessments
* Had contraindications to the medications used in the study protocol and regional anesthesia.
* History of alcohol or substance abuse within two years prior to surgery,
* Allergies to medication used in the study protocol
* Pregnancy.
18 Years
ALL
No
Sponsors
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Queen Savang Vadhana Memorial Hospital, Thailand
OTHER
Responsible Party
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Sophitnapa Tanasittiboon
Principal Investigator
Principal Investigators
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Sophitnapa Tanasittiboon, Anesthesiologist
Role: STUDY_DIRECTOR
Queen Savang Vadhana Memorial Hospital, Thailand
Locations
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Queen Savang Vadhana Memorial Hospital
Chon Buri, Changwat Chon Buri, Thailand
Countries
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Other Identifiers
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047/2566
Identifier Type: -
Identifier Source: org_study_id
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