An Intrinsic Capacity Identification and Management Programme for Older Adults in Singapore's Primary Care
NCT ID: NCT06753643
Last Updated: 2024-12-31
Study Results
Results pending
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
Recruitment Status
NOT_YET_RECRUITING
Total Enrollment
180 participants
Study Classification
OBSERVATIONAL
Study Start Date
2025-03-01
Study Completion Date
2026-02-28
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
The IMPACTFrail program is an intrinsic capacity (IC) identification and management program for mildly frail older adults. Specifically, it delivers the three-tier approach recommended in the National Frailty Strategy Policy Report. The program's core functions include the segmentation of older persons using the Clinical Frailty Scale (CFS) score followed by secondary IC screening for CFS 4 to 5 (Tier 1), follow-up clinical assessment to confirm IC losses (Tier 2) and needs-directed management and tracking of their health (Tier 3).
The investigator aims to conduct a multi-site feasibility study on a small group of older adult study participants (n=30 per polyclinic).
The feasibility study has a few components. First, a qualitative study will assess its feasibility (implementation, appropriateness, acceptability, practicality, adaptability) as perceived by older adults, healthcare providers, and healthcare administrators. Second, the investigator aims to collect process indicators to track its implementation progress. Third, program costs will be estimated. Fourth, the investigator will develop a logic model and theory of change, and cluster-specific detailed written program descriptions. Lastly, the investigator aims to triangulate the findings and assess the feasibility for larger-scale implementation. This study is guided by implementation science frameworks and guidelines for conducting feasibility studies.
The investigator aims to conduct a multi-site feasibility study on a small group of older adult study participants (n=30 per polyclinic).
The feasibility study has a few components. First, a qualitative study will assess its feasibility (implementation, appropriateness, acceptability, practicality, adaptability) as perceived by older adults, healthcare providers, and healthcare administrators. Second, the investigator aims to collect process indicators to track its implementation progress. Third, program costs will be estimated. Fourth, the investigator will develop a logic model and theory of change, and cluster-specific detailed written program descriptions. Lastly, the investigator aims to triangulate the findings and assess the feasibility for larger-scale implementation. This study is guided by implementation science frameworks and guidelines for conducting feasibility studies.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Background:
The broad goal for older adults is to age well and have healthy ageing. WHO defines healthy ageing as "the process of developing and maintaining the functional ability that enables wellbeing in older age." Functional ability is about having the capabilities that enable all people to be and do what they have reason to value.
Frailty is a clinically recognisable state whereby an older person's ability to cope with daily or acute stressors is compromised as a result of vulnerability from age-related deterioration in physiological reserves and function across multiple organ systems. Frailty is associated with negative health outcomes and is expected to increase in Singapore's ageing population. The National Frailty Strategy Policy Report published in 2023 serves to guide the Singapore Ministry of Health (MOH) Frailty Policy Implementation Workgroup in implementing the National Frailty Policy (NFP). One of the gaps identified in the report was the need for coordinated care and continuity of care across health and social service providers for frail older adults. To address this gap in Singapore's primary care setting, the IMPACTFrail program's core functions are to conduct segmentation of older people by using the Clinical Frailty Scale (CFS) score followed by secondary intrinsic capacity (IC) screening of six domains (locomotion, vision, hearing, vitality, cognition, psychological capacity) for CFS 4 and 5 (Tier 1), follow-up assessments based on IC deficits detected at screening (Tier 2), and coordination, management, and tracking (Tier 3). This study aims to co-develop IMPACTFrail's intervention components and implementation strategies in a small number of polyclinics and test its feasibility using implementation research in real-world local contexts.
Methods:
Prior to this pilot feasibility study, the investigators co-developed the innovation and implementation strategies among GERI, polyclinic cluster representatives, and implementers. This will be guided by the UK Medical Research Council's Framework (MRC) for developing and evaluating complex interventions and Framework of Actions for Intervention Development (FAID). Informal FGDs and interviews with stakeholders were conducted and the findings used to inform the development of the innovation. ERIC strategies will be selected to address CFIR barriers identified from the FGDs/interviews and specify and develop them.
Here, the investigators aim to conduct a multi-site feasibility study, with a few components. Each polyclinic has highly contextualised barriers, workflows, and infrastructure. Thus, each polyclinic is conceptualised as a single site for feasibility testing. There is no comparator arm.
First, FGDs/IDIs will be conducted to assess the program's feasibility (implementation, acceptability, practicality, adaptability) as perceived by older adults, healthcare providers, and healthcare administrators.
Second, the investigators aim to collect process indicators to track the program's implementation progress.
Third, program costs will be estimated.
Fourth, the investigators will develop a logic model and theory of change, and cluster-specific detailed written program descriptions.
Lastly, the investigators aim to triangulate our findings and assess the feasibility for larger-scale implementation.
This study is guided by implementation science frameworks and guidelines for conducting feasibility studies.
Discussion:
This project aims to improve the lives of older people through early detection and management of IC deficits for those with mild frailty (CFS 4-5) in primary care. This promotes longer-term outcomes including functional ability, improved quality of life, reduced healthcare use, and lower mortality.
Additionally:
First, the project translates evidence on the optimisation of IC and functional ability for healthy ageing to practice and policy in Singapore's primary care. Second, there is knowledge creation. This study contributes to the local evidence on screening and management strategies for delaying frailty progression by addressing IC deficits in frail older persons. The investigators inform the adaptations to implement the WHO ICOPE framework in local primary care contexts. Additionally, the project contributes to a better understanding on the optimisation of resources to groups who may benefit the most, by targeting CFS 4 and 5 for IC screening and delivering resource-intensive assessment and downstream interventions to this subgroup. Third, this study involves engaging all three clusters from the outset to accelerate national-level implementation and scaling up.
Additionally, to increase the likelihood of scalability, the investigators will involve 3 clusters and 1-2 polyclinics from each cluster. Fourth, the study offers opportunities for knowledge exchange.
Lastly, the project is aligned with national strategies like HealthierSG (informs frailty protocols for management in primary care), Age Well SG (enables frail community-dwelling persons to age in place), and the 2023 Action Plan for Successful Ageing (optimising IC and functional ability through a health program).
The broad goal for older adults is to age well and have healthy ageing. WHO defines healthy ageing as "the process of developing and maintaining the functional ability that enables wellbeing in older age." Functional ability is about having the capabilities that enable all people to be and do what they have reason to value.
Frailty is a clinically recognisable state whereby an older person's ability to cope with daily or acute stressors is compromised as a result of vulnerability from age-related deterioration in physiological reserves and function across multiple organ systems. Frailty is associated with negative health outcomes and is expected to increase in Singapore's ageing population. The National Frailty Strategy Policy Report published in 2023 serves to guide the Singapore Ministry of Health (MOH) Frailty Policy Implementation Workgroup in implementing the National Frailty Policy (NFP). One of the gaps identified in the report was the need for coordinated care and continuity of care across health and social service providers for frail older adults. To address this gap in Singapore's primary care setting, the IMPACTFrail program's core functions are to conduct segmentation of older people by using the Clinical Frailty Scale (CFS) score followed by secondary intrinsic capacity (IC) screening of six domains (locomotion, vision, hearing, vitality, cognition, psychological capacity) for CFS 4 and 5 (Tier 1), follow-up assessments based on IC deficits detected at screening (Tier 2), and coordination, management, and tracking (Tier 3). This study aims to co-develop IMPACTFrail's intervention components and implementation strategies in a small number of polyclinics and test its feasibility using implementation research in real-world local contexts.
Methods:
Prior to this pilot feasibility study, the investigators co-developed the innovation and implementation strategies among GERI, polyclinic cluster representatives, and implementers. This will be guided by the UK Medical Research Council's Framework (MRC) for developing and evaluating complex interventions and Framework of Actions for Intervention Development (FAID). Informal FGDs and interviews with stakeholders were conducted and the findings used to inform the development of the innovation. ERIC strategies will be selected to address CFIR barriers identified from the FGDs/interviews and specify and develop them.
Here, the investigators aim to conduct a multi-site feasibility study, with a few components. Each polyclinic has highly contextualised barriers, workflows, and infrastructure. Thus, each polyclinic is conceptualised as a single site for feasibility testing. There is no comparator arm.
First, FGDs/IDIs will be conducted to assess the program's feasibility (implementation, acceptability, practicality, adaptability) as perceived by older adults, healthcare providers, and healthcare administrators.
Second, the investigators aim to collect process indicators to track the program's implementation progress.
Third, program costs will be estimated.
Fourth, the investigators will develop a logic model and theory of change, and cluster-specific detailed written program descriptions.
Lastly, the investigators aim to triangulate our findings and assess the feasibility for larger-scale implementation.
This study is guided by implementation science frameworks and guidelines for conducting feasibility studies.
Discussion:
This project aims to improve the lives of older people through early detection and management of IC deficits for those with mild frailty (CFS 4-5) in primary care. This promotes longer-term outcomes including functional ability, improved quality of life, reduced healthcare use, and lower mortality.
Additionally:
First, the project translates evidence on the optimisation of IC and functional ability for healthy ageing to practice and policy in Singapore's primary care. Second, there is knowledge creation. This study contributes to the local evidence on screening and management strategies for delaying frailty progression by addressing IC deficits in frail older persons. The investigators inform the adaptations to implement the WHO ICOPE framework in local primary care contexts. Additionally, the project contributes to a better understanding on the optimisation of resources to groups who may benefit the most, by targeting CFS 4 and 5 for IC screening and delivering resource-intensive assessment and downstream interventions to this subgroup. Third, this study involves engaging all three clusters from the outset to accelerate national-level implementation and scaling up.
Additionally, to increase the likelihood of scalability, the investigators will involve 3 clusters and 1-2 polyclinics from each cluster. Fourth, the study offers opportunities for knowledge exchange.
Lastly, the project is aligned with national strategies like HealthierSG (informs frailty protocols for management in primary care), Age Well SG (enables frail community-dwelling persons to age in place), and the 2023 Action Plan for Successful Ageing (optimising IC and functional ability through a health program).
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Healthy Ageing
Frailty
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
Observational Model Type
OTHER
Study Time Perspective
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Older Adults (programme recipients)
These are the recipients of the new programme in this feasibility study.
Main study components of direct involvement. Qualitative - Focus group discussions or in-depth interviews with programme recipients
Quantitative - Monitoring process indicators
The IMPACTFrail programme
Intervention Type
OTHER
The IMPACTFrail programme
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
The IMPACTFrail programme
The IMPACTFrail programme
Intervention Type
OTHER
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* being a patient of the polyclinic site
* aged 60 years and above
* Clinical frailty score (CFS) of 4 - 5
* Not done comprehensive geriatric assessment (CGA) in the past 12 months (based on available medical records or self-report)
* Not a current patient of geriatric specialist outpatient clinic (based on available medical records or self-report).
Healthcare Staff (for qualitative study)
* aged 21 years and above
* Involved in the IMPACTFrail program as an implementer and/or a healthcare administrator with authority to make implementation decisions.
* aged 60 years and above
* Clinical frailty score (CFS) of 4 - 5
* Not done comprehensive geriatric assessment (CGA) in the past 12 months (based on available medical records or self-report)
* Not a current patient of geriatric specialist outpatient clinic (based on available medical records or self-report).
Healthcare Staff (for qualitative study)
* aged 21 years and above
* Involved in the IMPACTFrail program as an implementer and/or a healthcare administrator with authority to make implementation decisions.
Minimum Eligible Age
60 Years
Maximum Eligible Age
100 Years
Eligible Sex
ALL
Accepts Healthy Volunteers
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
National Healthcare Group Polyclinics
OTHER_GOV
Sponsor Role
collaborator
National University Polyclinics
UNKNOWN
Sponsor Role
collaborator
SingHealth Polyclinics
OTHER
Sponsor Role
collaborator
Geriatric Education and Research Institute
OTHER_GOV
Sponsor Role
lead
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Responsibility Role
SPONSOR
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Grace Sum, PhD
Role: PRINCIPAL_INVESTIGATOR
Geriatric Education and Research Institute
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
References
Explore related publications, articles, or registry entries linked to this study.
O'Donovan MR, Sezgin D, Liew A, O'Caoimh R. Burden of disease, disability-adjusted life years and frailty prevalence. QJM. 2019 Apr 1;112(4):261-267. doi: 10.1093/qjmed/hcy291.
Reference Type
BACKGROUND
Milat A, Lee K, Conte K, Grunseit A, Wolfenden L, van Nassau F, Orr N, Sreeram P, Bauman A. Intervention Scalability Assessment Tool: A decision support tool for health policy makers and implementers. Health Res Policy Syst. 2020 Jan 3;18(1):1. doi: 10.1186/s12961-019-0494-2.
Reference Type
BACKGROUND
Stoyanov SR, Hides L, Kavanagh DJ, Wilson H. Development and Validation of the User Version of the Mobile Application Rating Scale (uMARS). JMIR Mhealth Uhealth. 2016 Jun 10;4(2):e72. doi: 10.2196/mhealth.5849.
Reference Type
BACKGROUND
Sutton E, Catling J, Segaert K, Veldhuijzen van Zanten J. Cognitive Health Worries, Reduced Physical Activity and Fewer Social Interactions Negatively Impact Psychological Wellbeing in Older Adults During the COVID-19 Pandemic. Front Psychol. 2022 Feb 17;13:823089. doi: 10.3389/fpsyg.2022.823089. eCollection 2022.
Reference Type
BACKGROUND
Lopez-Teros T, Gutierrez-Robledo LM, Perez-Zepeda MU. Gait Speed and Handgrip Strength as Predictors of Incident Disability in Mexican Older Adults. J Frailty Aging. 2014;3(2):109-12. doi: 10.14283/jfa.2014.10.
Reference Type
BACKGROUND
Tan WS, Nai ZL, Tan HTR, Nicholas S, Choo R, Ginting ML, Tan E, Teng PHJ, Lim WS, Wong CH, Ding YY; Geriatric Services Hub Programme Group. Protocol for a mixed-methods and multi-site assessment of the implementation process and outcomes of a new community-based frailty programme. BMC Geriatr. 2022 Jul 15;22(1):586. doi: 10.1186/s12877-022-03254-6.
Reference Type
BACKGROUND
Grigor'ev EG, Pankratova VA, Cherkashin AF. [Case of severe combined trauma]. Khirurgiia (Mosk). 1979 Oct;(10):109-10. No abstract available. Russian.
Reference Type
BACKGROUND
Tulloch AJ, Moore V. A randomized controlled trial of geriatric screening and surveillance in general practice. J R Coll Gen Pract. 1979 Dec;29(209):733-40.
Reference Type
BACKGROUND
Hyzy M, Bond R, Mulvenna M, Bai L, Dix A, Leigh S, Hunt S. System Usability Scale Benchmarking for Digital Health Apps: Meta-analysis. JMIR Mhealth Uhealth. 2022 Aug 18;10(8):e37290. doi: 10.2196/37290.
Reference Type
BACKGROUND
Kwan YH, Yoon S, Tan CS, Tai BC, Tan WB, Phang JK, Tan NC, Tan CYL, Quah YL, Koot D, Teo HH, Low LL. EMPOWERing Patients With Diabetes Using Profiling and Targeted Feedbacks Delivered Through Smartphone App and Wearable (EMPOWER): Protocol for a Randomized Controlled Trial on Effectiveness and Implementation. Front Public Health. 2022 Feb 25;10:805856. doi: 10.3389/fpubh.2022.805856. eCollection 2022.
Reference Type
BACKGROUND
Tay LB, Chua MP, Tay EL, Chan HN, Mah SM, Latib A, Wong CQ, Ng YS. Multidomain Geriatric Screen and Physical Fitness Assessment Identify Prefrailty/Frailty and Potentially Modifiable Risk Factors in Community-Dwelling Older Adults. Ann Acad Med Singap. 2019 Jun;48(6):171-180.
Reference Type
BACKGROUND
Proctor E, Silmere H, Raghavan R, Hovmand P, Aarons G, Bunger A, Griffey R, Hensley M. Outcomes for implementation research: conceptual distinctions, measurement challenges, and research agenda. Adm Policy Ment Health. 2011 Mar;38(2):65-76. doi: 10.1007/s10488-010-0319-7.
Reference Type
BACKGROUND
Powell BJ, Waltz TJ, Chinman MJ, Damschroder LJ, Smith JL, Matthieu MM, Proctor EK, Kirchner JE. A refined compilation of implementation strategies: results from the Expert Recommendations for Implementing Change (ERIC) project. Implement Sci. 2015 Feb 12;10:21. doi: 10.1186/s13012-015-0209-1.
Reference Type
BACKGROUND
Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009 Aug 7;4:50. doi: 10.1186/1748-5908-4-50.
Reference Type
BACKGROUND
Smith JD, Li DH, Rafferty MR. The Implementation Research Logic Model: a method for planning, executing, reporting, and synthesizing implementation projects. Implement Sci. 2020 Sep 25;15(1):84. doi: 10.1186/s13012-020-01041-8.
Reference Type
BACKGROUND
Pua YH, Tay L, Clark RA, Thumboo J, Tay EL, Mah SM, Ng YS. Screening accuracy of percentage predicted gait speed for prefrailty/frailty in community-dwelling older adults. Geriatr Gerontol Int. 2022 Aug;22(8):575-580. doi: 10.1111/ggi.14418. Epub 2022 Jun 18.
Reference Type
BACKGROUND
Pua YH, Tay L, Clark RA, Thumboo J, Tay EL, Mah SM, Ng YS. Reference Ranges for Gait Speed and Sit-to-Stand Performance in a Cohort of Mobility-Intact Community-Dwelling Older Adults From Singapore. J Am Med Dir Assoc. 2022 Sep;23(9):1579-1584.e1. doi: 10.1016/j.jamda.2021.12.045. Epub 2022 Feb 10.
Reference Type
BACKGROUND
Clark RA, Pua YH, Bower KJ, Bechard L, Hough E, Charlton PC, Mentiplay B. Validity of a low-cost laser with freely available software for improving measurement of walking and running speed. J Sci Med Sport. 2019 Feb;22(2):212-216. doi: 10.1016/j.jsams.2018.07.005. Epub 2018 Jul 17.
Reference Type
BACKGROUND
Van Damme J, Neiterman E, Oremus M, Lemmon K, Stolee P. Perspectives of older adults, caregivers, and healthcare providers on frailty screening: a qualitative study. BMC Geriatr. 2020 Feb 17;20(1):65. doi: 10.1186/s12877-020-1459-6.
Reference Type
BACKGROUND
Preston L, Chambers D, Campbell F, Cantrell A, Turner J, Goyder E. What evidence is there for the identification and management of frail older people in the emergency department? A systematic mapping review. Southampton (UK): NIHR Journals Library; 2018 Apr. Available from http://www.ncbi.nlm.nih.gov/books/NBK493681/
Reference Type
BACKGROUND
Dent E, Martin FC, Bergman H, Woo J, Romero-Ortuno R, Walston JD. Management of frailty: opportunities, challenges, and future directions. Lancet. 2019 Oct 12;394(10206):1376-1386. doi: 10.1016/S0140-6736(19)31785-4.
Reference Type
BACKGROUND
Welstead M, Luciano M, Russ TC, Muniz-Terrera G. Heterogeneity of Frailty Trajectories and Associated Factors in the Lothian Birth Cohort 1936. Gerontology. 2022;68(8):861-868. doi: 10.1159/000519240. Epub 2021 Sep 29.
Reference Type
BACKGROUND
Tanaka T, Takahashi K, Hirano H, Kikutani T, Watanabe Y, Ohara Y, Furuya H, Tetsuo T, Akishita M, Iijima K. Oral Frailty as a Risk Factor for Physical Frailty and Mortality in Community-Dwelling Elderly. J Gerontol A Biol Sci Med Sci. 2018 Nov 10;73(12):1661-1667. doi: 10.1093/gerona/glx225.
Reference Type
BACKGROUND
Fourteau M, Virecoulon Giudici K, Rolland Y, Vellas B, de Souto Barreto P. Associations Between Multidomain Lifestyle Interventions and Intrinsic Capacity Domains During Aging: A Narrative Review. JAR Life. 2020 Sep 3;9:16-25. doi: 10.14283/jarlife.2020.6. eCollection 2020.
Reference Type
BACKGROUND
Bevilacqua R, Soraci L, Stara V, Riccardi GR, Corsonello A, Pelliccioni G, Lattanzio F, Casaccia S, Moller J, Wieching R, Ogawa T, Watanabe S, Kokobun K, Kondo I, Takano E, Maranesi E. A systematic review of multidomain and lifestyle interventions to support the intrinsic capacity of the older population. Front Med (Lausanne). 2022 Jul 15;9:929261. doi: 10.3389/fmed.2022.929261. eCollection 2022.
Reference Type
BACKGROUND
Cameron ID, Fairhall N, Langron C, Lockwood K, Monaghan N, Aggar C, Sherrington C, Lord SR, Kurrle SE. A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial. BMC Med. 2013 Mar 11;11:65. doi: 10.1186/1741-7015-11-65.
Reference Type
BACKGROUND
Ng TP, Feng L, Nyunt MS, Feng L, Niti M, Tan BY, Chan G, Khoo SA, Chan SM, Yap P, Yap KB. Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial. Am J Med. 2015 Nov;128(11):1225-1236.e1. doi: 10.1016/j.amjmed.2015.06.017. Epub 2015 Jul 6.
Reference Type
BACKGROUND
Chew J, Lim JP, Yew S, Yeo A, Ismail NH, Ding YY, Lim WS. Disentangling the Relationship between Frailty and Intrinsic Capacity in Healthy Community-Dwelling Older Adults: A Cluster Analysis. J Nutr Health Aging. 2021;25(9):1112-1118. doi: 10.1007/s12603-021-1679-2.
Reference Type
BACKGROUND
Lim YJ, Ng YS, Sultana R, Tay EL, Mah SM, Chan CHN, Latib AB, Abu-Bakar HM, Ho JCY, Kwek THH, Tay L. Frailty Assessment in Community-Dwelling Older Adults: A Comparison of 3 Diagnostic Instruments. J Nutr Health Aging. 2020;24(6):582-590. doi: 10.1007/s12603-020-1396-2.
Reference Type
BACKGROUND
Yu R, Amuthavalli Thiyagarajan J, Leung J, Lu Z, Kwok T, Woo J. Validation of the Construct of Intrinsic Capacity in a Longitudinal Chinese Cohort. J Nutr Health Aging. 2021;25(6):808-815. doi: 10.1007/s12603-021-1637-z.
Reference Type
BACKGROUND
Zeng X, Shen S, Xu L, Wang Y, Yang Y, Chen L, Guan H, Zhang J, Chen X. The Impact of Intrinsic Capacity on Adverse Outcomes in Older Hospitalized Patients: A One-Year Follow-Up Study. Gerontology. 2021;67(3):267-275. doi: 10.1159/000512794. Epub 2021 Mar 18.
Reference Type
BACKGROUND
Belloni G, Cesari M. Frailty and Intrinsic Capacity: Two Distinct but Related Constructs. Front Med (Lausanne). 2019 Jun 18;6:133. doi: 10.3389/fmed.2019.00133. eCollection 2019.
Reference Type
BACKGROUND
Portegijs E, Rantakokko M, Viljanen A, Sipila S, Rantanen T. Identification of Older People at Risk of ADL Disability Using the Life-Space Assessment: A Longitudinal Cohort Study. J Am Med Dir Assoc. 2016 May 1;17(5):410-4. doi: 10.1016/j.jamda.2015.12.010. Epub 2016 Jan 21.
Reference Type
BACKGROUND
Portegijs E, Rantakokko M, Viljanen A, Sipila S, Rantanen T. Is frailty associated with life-space mobility and perceived autonomy in participation outdoors? A longitudinal study. Age Ageing. 2016 Jul;45(4):550-3. doi: 10.1093/ageing/afw072. Epub 2016 Apr 28.
Reference Type
BACKGROUND
Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA; Cardiovascular Health Study Collaborative Research Group. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56. doi: 10.1093/gerona/56.3.m146.
Reference Type
BACKGROUND
Ma L, Chhetri JK, Zhang Y, Liu P, Chen Y, Li Y, Chan P. Integrated Care for Older People Screening Tool for Measuring Intrinsic Capacity: Preliminary Findings From ICOPE Pilot in China. Front Med (Lausanne). 2020 Nov 30;7:576079. doi: 10.3389/fmed.2020.576079. eCollection 2020.
Reference Type
BACKGROUND
Tavassoli N, de Souto Barreto P, Berbon C, Mathieu C, de Kerimel J, Lafont C, Takeda C, Carrie I, Piau A, Jouffrey T, Andrieu S, Nourhashemi F, Beard JR, Soto Martin ME, Vellas B. Implementation of the WHO integrated care for older people (ICOPE) programme in clinical practice: a prospective study. Lancet Healthy Longev. 2022 Jun;3(6):e394-e404. doi: 10.1016/S2666-7568(22)00097-6. Epub 2022 Jun 9.
Reference Type
BACKGROUND
Kojima G, Taniguchi Y, Iliffe S, Jivraj S, Walters K. Transitions between frailty states among community-dwelling older people: A systematic review and meta-analysis. Ageing Res Rev. 2019 Mar;50:81-88. doi: 10.1016/j.arr.2019.01.010. Epub 2019 Jan 16.
Reference Type
BACKGROUND
Liu S, Kang L, Liu X, Zhao S, Wang X, Li J, Jiang S. Trajectory and Correlation of Intrinsic Capacity and Frailty in a Beijing Elderly Community. Front Med (Lausanne). 2021 Dec 9;8:751586. doi: 10.3389/fmed.2021.751586. eCollection 2021.
Reference Type
BACKGROUND
Dent E, Morley JE, Cruz-Jentoft AJ, Woodhouse L, Rodriguez-Manas L, Fried LP, Woo J, Aprahamian I, Sanford A, Lundy J, Landi F, Beilby J, Martin FC, Bauer JM, Ferrucci L, Merchant RA, Dong B, Arai H, Hoogendijk EO, Won CW, Abbatecola A, Cederholm T, Strandberg T, Gutierrez Robledo LM, Flicker L, Bhasin S, Aubertin-Leheudre M, Bischoff-Ferrari HA, Guralnik JM, Muscedere J, Pahor M, Ruiz J, Negm AM, Reginster JY, Waters DL, Vellas B. Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management. J Nutr Health Aging. 2019;23(9):771-787. doi: 10.1007/s12603-019-1273-z.
Reference Type
BACKGROUND
Gutierrez-Robledo LM, Garcia-Chanes RE, Gonzalez-Bautista E, Rosas-Carrasco O. Validation of Two Intrinsic Capacity Scales and Its Relationship with Frailty and Other Outcomes in Mexican Community-Dwelling Older Adults. J Nutr Health Aging. 2021;25(1):33-40. doi: 10.1007/s12603-020-1555-5.
Reference Type
BACKGROUND
Lee JQ, Ding YY, Latib A, et alINtrinsic Capacity and its RElAtionship With Life-SpacE Mobility (INCREASE): a cross-sectional study of community-dwelling older adults in SingaporeBMJ Open 2021;11:e054705. doi: 10.1136/bmjopen-2021-054705
Reference Type
BACKGROUND
World Health Organization. The International Classification of functioning, disability and health. 1149. The International Classification of Functioning, Disability and Health 2002: 1-22
Reference Type
BACKGROUND
Woo, J. Frailty, Successful Aging, Resilience, and Intrinsic Capacity: a Cross-disciplinary Discourse of the Aging Process. Curr Geri Rep 8, 67-71 (2019). https://doi.org/10.1007/s13670-019-0276-2
Reference Type
BACKGROUND
Vermeiren S, Vella-Azzopardi R, Beckwee D, Habbig AK, Scafoglieri A, Jansen B, Bautmans I; Gerontopole Brussels Study group. Frailty and the Prediction of Negative Health Outcomes: A Meta-Analysis. J Am Med Dir Assoc. 2016 Dec 1;17(12):1163.e1-1163.e17. doi: 10.1016/j.jamda.2016.09.010.
Reference Type
BACKGROUND
Beard JR, Si Y, Liu Z, Chenoweth L, Hanewald K. Intrinsic Capacity: Validation of a New WHO Concept for Healthy Aging in a Longitudinal Chinese Study. J Gerontol A Biol Sci Med Sci. 2022 Jan 7;77(1):94-100. doi: 10.1093/gerona/glab226.
Reference Type
BACKGROUND
Tay L, Tay EL, Mah SM, Latib A, Koh C, Ng YS. Association of Intrinsic Capacity with Frailty, Physical Fitness and Adverse Health Outcomes in Community-Dwelling Older Adults. J Frailty Aging. 2023;12(1):7-15. doi: 10.14283/jfa.2022.28.
Reference Type
BACKGROUND
Liu S, Yu X, Wang X, Li J, Jiang S, Kang L, Liu X. Intrinsic Capacity predicts adverse outcomes using Integrated Care for Older People screening tool in a senior community in Beijing. Arch Gerontol Geriatr. 2021 May-Jun;94:104358. doi: 10.1016/j.archger.2021.104358. Epub 2021 Jan 28. No abstract available.
Reference Type
BACKGROUND
Beard JR, Jotheeswaran AT, Cesari M, Araujo de Carvalho I. The structure and predictive value of intrinsic capacity in a longitudinal study of ageing. BMJ Open. 2019 Nov 2;9(11):e026119. doi: 10.1136/bmjopen-2018-026119.
Reference Type
BACKGROUND
Cesari M, Araujo de Carvalho I, Amuthavalli Thiyagarajan J, Cooper C, Martin FC, Reginster JY, Vellas B, Beard JR. Evidence for the Domains Supporting the Construct of Intrinsic Capacity. J Gerontol A Biol Sci Med Sci. 2018 Nov 10;73(12):1653-1660. doi: 10.1093/gerona/gly011.
Reference Type
BACKGROUND
Beard JR, Officer AM, Cassels AK. The World Report on Ageing and Health. Gerontologist. 2016 Apr;56 Suppl 2:S163-6. doi: 10.1093/geront/gnw037. No abstract available.
Reference Type
BACKGROUND
Chen C, Lim JT, Chia NC, Wang L, Tysinger B, Zissimopolous J, Chong MZ, Wang Z, Koh GC, Yuan JM, Tan KB, Chia KS, Cook AR, Malhotra R, Chan A, Ma S, Ng TP, Koh WP, Goldman DP, Yoong J. The Long-Term Impact of Functional Disability on Hospitalization Spending in Singapore. J Econ Ageing. 2019;14:100193. doi: 10.1016/j.jeoa.2019.02.002. Epub 2019 Feb 27.
Reference Type
BACKGROUND
Related Links
Access external resources that provide additional context or updates about the study.
https://www.worldometers.info/demographics/life-expectancy/
1\. Life expectancy at birth. Data based on the latest United Nations Population Division estimates.
https://apps.who.int/iris/handle/10665/42682
WHO. Adherence to long term therapies: evidence for action. 2003.
https://www.imda.gov.sg/-/media/Imda/Files/
59\. Infocomm Media Development Authority. Annual survey on infocomm usagein households and by individuals for 2017. Singapore: Infocomm Media Development Authority 2018.
https://www.healthcareitnews.com/news/asia/singapore-survey-finds-elderly-unreceptive-digital-health-services
Singapore survey finds elderly unreceptive to digital health services. Health IT News. July 2021
https://www.who.int/publications/i/item/9789241515993
Integrated care for older people. Implementation framework. Guidance for systems and services. World Health Organization
https://www.afro.who.int/publications/handbook-guidance-person-centred-assessment-and-pathways-primary-care
Guidance on person-centred assessment and pathways in primary care. Handbook. World Health Organization
https://www.who.int/publications/i/item/9789241565042
World Report on Ageing and Health. World Health Organization; 2015
https://www.who.int/publications/i/item/9789240048355
WHO. Integrated care for older people (ICOPE) implementation programme: findings from the "ready" phase.
https://www.who.int/publications/i/item/9789241550109
WHO . Integrated care for older people: guidelines on community-level interventions to manage declines in intrinsic capacity. Geneva: World Health Organization 2017
https://www.who.int/publications/i/item/WHO-FWC-ALC-17.2
WHO Clinical Consortium on Healthy Ageing. Report of consortium meeting 1-2 December 2016 in Geneva, Switzerland. Geneva: World Health Organization 2017
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
GERI1637
Identifier Type: -
Identifier Source: org_study_id