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Can Total Mechanical Power Be a Determinant of Weaning Failure in Chronic Obstructive Pulmonary Disease (COPD)?

NCT ID: NCT06751654

Last Updated: 2024-12-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-12-06

Study Completion Date

2024-12-23

Brief Summary

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A Comparison of Ventilator Parameters (TV, DP, Total Mechanical Power, etc.) Between Successfully and unsuccessfully Weaned Patients with COPD Undergoing Mechanical Ventilation Due to Respiratory Failure, and Diagnosed with Pneumonia or ARDS in the Intensive Care Unit."

Detailed Description

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The objective of this study is to investigate which mechanical ventilation parameters and clinical findings influence weaning success by comparing successful and unsuccessful weaning patient groups among patients diagnosed with COPD who were intubated and monitored for more than five days in the intensive care unit. The findings of this study may contribute to the development of future treatment protocols and criteria for evaluating the weaning process.

This study is planned to be conducted in two centers: Bakırköy Dr. Sadi Konuk Training and Research Hospital in Istanbul and Shahid Beheshti University of Medical Sciences, Masih Daneshvari Hospital in Tehran. This multicenter study aims to facilitate the comparison of data obtained under different geographical and clinical conditions, thereby enabling a broader analysis of factors influencing the weaning process across a larger patient population.

Conditions

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COPD (Chronic Obstructive Pulmonary Disease) ARDS (Acute Respiratory Distress Syndrome) Mechanical Power Pneumonia Weaning Failure

Keywords

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Mechanical Power COPD

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Weaned

patients with successful weaning from mechanic ventilator

No interventions assigned to this group

Non-weaned

patients who have failed to wean from ventilator

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 years and older
* COPD-diagnosed patients who have been intubated and stayed in the ICU for more than 5 days

Exclusion Criteria

* Patients without electronic medical records
* Patients under 18 years of age
* Patients diagnosed with pulmonary malignancy
* Patients who stayed in the ICU for less than 5 days
* Patients monitored in the ICU without intubation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Masih Daneshvari Hospital

OTHER

Sponsor Role collaborator

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zafer Cukurova, M.D

Role: STUDY_CHAIR

Bakırkoy Dr. Sadi Konuk Training and Research Hospital

Seyed Mohammadreza Hashemian, M.D

Role: STUDY_DIRECTOR

Masih Daneshvari Hospital

Locations

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Bakirkoy Dr Sadi Konuk Research and Training Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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2024-12-06

Identifier Type: -

Identifier Source: org_study_id