Can Total Mechanical Power Be a Determinant of Weaning Failure in Chronic Obstructive Pulmonary Disease (COPD)?

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-12-06

Study Completion Date

2024-12-23

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A Comparison of Ventilator Parameters (TV, DP, Total Mechanical Power, etc.) Between Successfully and unsuccessfully Weaned Patients with COPD Undergoing Mechanical Ventilation Due to Respiratory Failure, and Diagnosed with Pneumonia or ARDS in the Intensive Care Unit."

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Evaluation of Mechanical Power and Ventilator Parameters to Predict Weaning Success in the Intensive Care Unit

NCT07268989

Weaning Mechanical Ventilation Mechanical Power Negative Inspiratory Force +1 more

RECRUITING

Comparing Mechanical Power in Different Inspiratory Times

NCT06413472

Ventilator-Induced Lung Injury Acute Respiratory Distress Syndrome

COMPLETED

Assessment of Ventilation Parameters for Extubation Prediction in ICU

NCT06531005

Acute Respiratory Failure Invasive Mechanical Ventilation

RECRUITING

Development of a Scoring and Prediction Model for Weaning Success in ARDS Patients Using Ventilation Parameters Combined with Artificial Intelligence and Deep Learning Techniques

NCT06751693

Deep Learning Artificial Intelegence ARDS (Acute Respiratory Distress Syndrome)

COMPLETED

Mechanical Power Versus Diaphragmatic Excursion As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients

NCT06510517

Mechanical Power

NOT_YET_RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The objective of this study is to investigate which mechanical ventilation parameters and clinical findings influence weaning success by comparing successful and unsuccessful weaning patient groups among patients diagnosed with COPD who were intubated and monitored for more than five days in the intensive care unit. The findings of this study may contribute to the development of future treatment protocols and criteria for evaluating the weaning process.

This study is planned to be conducted in two centers: Bakırköy Dr. Sadi Konuk Training and Research Hospital in Istanbul and Shahid Beheshti University of Medical Sciences, Masih Daneshvari Hospital in Tehran. This multicenter study aims to facilitate the comparison of data obtained under different geographical and clinical conditions, thereby enabling a broader analysis of factors influencing the weaning process across a larger patient population.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

COPD (Chronic Obstructive Pulmonary Disease) ARDS (Acute Respiratory Distress Syndrome) Mechanical Power Pneumonia Weaning Failure

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Weaned

patients with successful weaning from mechanic ventilator

No interventions assigned to this group

Non-weaned

patients who have failed to wean from ventilator

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients aged 18 years and older
* COPD-diagnosed patients who have been intubated and stayed in the ICU for more than 5 days

Exclusion Criteria

* Patients without electronic medical records
* Patients under 18 years of age
* Patients diagnosed with pulmonary malignancy
* Patients who stayed in the ICU for less than 5 days
* Patients monitored in the ICU without intubation

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No