Comparison of the Effects of Mirror Therapy,rTMS and Robotic-assisted Hand Therapy in Stroke Patients
NCT ID: NCT06750692
Last Updated: 2024-12-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
120 participants
INTERVENTIONAL
2024-12-27
2026-06-20
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Experimental: Mirror therapy
The first group of participants will receive mirror therapy for 4 weeks, 5 sessions per week for a total of 20 sessions of upper extremity mirror therapy.
Procedure: Mirror therapy
The first group of participants will receive a total of 20 sessions of upper extremity mirror therapy program, 5 sessions per week for 4 weeks.
Experimental: Low Frequency rTMS Protocol
The second group will receive a total of 20 sessions of Repetitive Transcranial Magnetic Stimulation (rTMS) to the contralateral M1 upper extremity motor cortex region at low frequency (1Hz) and intensity of 100%-110% of the resting motor threshold, 5 sessions per week for 4 weeks.
Device: Low Frequency rTMS Protocol
Repetitive Transcranial Magnetic Stimulation (rTMS) will be applied at an intensity of 100-110% of the resting motor threshold and low frequency (1 Hz) to the contralateral M1 upper extremity motor cortex region for a total of 20 sessions, 5 sessions per week for 4 weeks. rTMS application is planned to provide magnetic stimulation with the stimulator of the Magventure MagPro R30 device.
Experimental: Robotic-assisted hand therapy
In the Robot Assisted Therapy group, a total of 20 sessions will be applied to the hemiplegic upper extremity with AMADEO (Tyromotion Austria) 5 days a week for 4 weeks.
Robotic-assisted hand therapy
In the Robot Assisted Therapy group, a total of 20 sessions will be applied 5 days a week for 4 weeks using continuous passive range of motion, active assistive exercise and play therapy programs for hemiplegic upper extremities with AMADEO (Tyromotion Austria).
Interventions
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Procedure: Mirror therapy
The first group of participants will receive a total of 20 sessions of upper extremity mirror therapy program, 5 sessions per week for 4 weeks.
Device: Low Frequency rTMS Protocol
Repetitive Transcranial Magnetic Stimulation (rTMS) will be applied at an intensity of 100-110% of the resting motor threshold and low frequency (1 Hz) to the contralateral M1 upper extremity motor cortex region for a total of 20 sessions, 5 sessions per week for 4 weeks. rTMS application is planned to provide magnetic stimulation with the stimulator of the Magventure MagPro R30 device.
Robotic-assisted hand therapy
In the Robot Assisted Therapy group, a total of 20 sessions will be applied 5 days a week for 4 weeks using continuous passive range of motion, active assistive exercise and play therapy programs for hemiplegic upper extremities with AMADEO (Tyromotion Austria).
Eligibility Criteria
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Inclusion Criteria
* stroke at least 3 months ago
* voluntarily agreed to participate in the study regularly, whose health status is suitable for rehabilitation and who are medically stable
* mini mental test score of 15 and above
* Neurologically stable patient
Exclusion Criteria
* history of epilepsy, antiepileptic drug use
* intracranial metal objects
* intraauricular implants
* cognitive dysfunction
* upper extremity peripheral nerve injuries
* malignancy
* active infection
* skin infections or open wounds in the application area
* inflammatory diseases
* orthopedic injuries that may limit maximum effort capacity
* brain lesion or drug use history that may affect the seizure threshold
* increased intracranial pressure
* uncontrolled migraine
* severe spasticity in the hand (MAS≥3)
* contracture in the hand
* have had a fracture or surgery on the hemiplegic side in the last 6 months
* severe visual impairment
* severe depression
40 Years
80 Years
ALL
No
Sponsors
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Afyonkarahisar Health Sciences University
OTHER
Responsible Party
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Selma Eroğlu
Associate Professor
Principal Investigators
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Selma Eroglu, MD
Role: PRINCIPAL_INVESTIGATOR
Afyonkarahisar Health Sciences University
Locations
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Afyonkarahisar Health Sciences University
Afyonkarahisar, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Sanberk Beklen, MD
Role: primary
References
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Suganuma Y, Shimode C, Yamamoto H. Conjugation in Tetrahymena: formation of a special junction area for conjugation during the co-stimulation period. J Electron Microsc (Tokyo). 1984;33(1):10-8. No abstract available.
Jia F, Zhao Y, Wang Z, Chen J, Lu S, Zhang M. Effect of Graded Motor Imagery Combined With Repetitive Transcranial Magnetic Stimulation on Upper Extremity Motor Function in Stroke Patients: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2024 May;105(5):819-825. doi: 10.1016/j.apmr.2023.12.002. Epub 2023 Dec 17.
The presidents. Frank Abbott, 1887-1888. J Am Dent Assoc. 1981 Apr;102(4):471. No abstract available.
Other Identifiers
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SBH2025
Identifier Type: -
Identifier Source: org_study_id