The Effects of Age on Wound Healing on Free Gingival Graft Surgery in the Treatment of Attached Keratinized Gingival Deficiency by Determining Clinical and Biochemical Outcomes
NCT ID: NCT06749119
Last Updated: 2024-12-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
30 participants
INTERVENTIONAL
2023-04-14
2024-12-27
Brief Summary
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Detailed Description
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Clinical parameters included measurement of probing depth (PD), clinical attachment level (CAL), bleeding of probing (BOP), plaque index (PI), gingival index (GI) at 6 sites per tooth except the third molars were measured at baseline and l, 3 and 6 months after surgery. Keratinized gingiva width, keratinized gingiva thickness of the operation sites were measured baseline and 1,3 and 6 months after surgery. Vertical dimension of the graft, horizontal dimension of the graft, graft thickness were measured at baseline and 1,3,6 months after surgery. Graft area measurements were calculated on standard photographs by a Java-based analysis program (ImageJ, National Institutes of Health, Bethesda, MD) to determine the shrinkage rate of the grafts. The graft shrinkage ratio was calculated as the difference between baseline to 1-month, baseline to 3-months, baseline to 6-month graft site value. Data were analyzed using appropriate statistical tests.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Young group: Aged 20-35 years
They received free gingival operation. Graft was harvested from palatal region and placed to the recipient site. Wound fluid samples were collected from 4 regions of the wound at baseline, 4-,7-,14-days. Clinical measurements were done at baseline, 1-,3-,6-months postoperatively.
Free gingival graft operation
Free gingival graft was harvested from palatal region and stabilized on the maxillary anterior recipient bed with sutures .
Adult group: Aged 50-65 years
They received free gingival operation. Graft was harvested from palatal region and placed to the recipient site. Wound fluid samples were collected from 4 regions of the wound at baseline, 4-,7-,14-days. Clinical measurements were done at baseline, 1-,3-,6-months postoperatively.
Free gingival graft operation
Free gingival graft was harvested from palatal region and stabilized on the maxillary anterior recipient bed with sutures .
Interventions
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Free gingival graft operation
Free gingival graft was harvested from palatal region and stabilized on the maxillary anterior recipient bed with sutures .
Eligibility Criteria
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Inclusion Criteria
* periodontally healthy with full-mouth bleeding and plaque score ≤ 10%
* no use of any drugs that will affect periodontal tissue health and healing process
* absence of any systemic condition or illness
Exclusion Criteria
* previous periodontal surgery
* a pathology in the apical region of the tooth
* pregnancy, lactation
20 Years
65 Years
ALL
Yes
Sponsors
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Marmara University
OTHER
Responsible Party
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Locations
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Marmara University Faculty of Dentistry
Istanbul, Maltepe, Turkey (Türkiye)
Countries
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Other Identifiers
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09.2020.660
Identifier Type: -
Identifier Source: org_study_id