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Effect of Cervical Epidural Steroid Injection With Neural Mobilization in Patients With Cervical Radicular Pain

NCT ID: NCT06747819

Last Updated: 2024-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-01

Study Completion Date

2025-02-28

Brief Summary

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This study examines the effectiveness of cervical epidural steroid injections (CESI) and neural mobilization (NM), individually and in combination, in alleviating cervical radicular pain-a condition characterized by nerve root compression or irritation often due to herniated discs or bony spurs. Cervical radiculopathy leads to chronic pain, sensory and motor deficits, and disability in the upper limbs.

Detailed Description

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The study is a randomized controlled trial conducted between April and October 2024, with patients diagnosed with cervical radicular pain randomized into three groups: CESI-only, NM-only, and combined CESI and NM.

Conditions

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Cervical Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Interventional group I

Group Type EXPERIMENTAL

Cervical Epidural Steroid Injection (CESI)

Intervention Type DIAGNOSTIC_TEST

Participants in this group received CESI to reduce inflammation and alleviate pain in the cervical nerve roots.

Interventional group II

Group Type ACTIVE_COMPARATOR

Neural Mobilization (NM)

Intervention Type COMBINATION_PRODUCT

Participants in this group underwent NM exercises aimed at improving nerve mobility and reducing symptoms related to nerve compression.

Interventions

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Cervical Epidural Steroid Injection (CESI)

Participants in this group received CESI to reduce inflammation and alleviate pain in the cervical nerve roots.

Intervention Type DIAGNOSTIC_TEST

Neural Mobilization (NM)

Participants in this group underwent NM exercises aimed at improving nerve mobility and reducing symptoms related to nerve compression.

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18-65 years, diagnosed with chronic cervical radicular pain.
* Patients with chronic cervical radicular pain (\>6 months).
* Patients who had been confirmed through clinical examination and imaging studies (MRI or CT) showed evidence of nerve root compression.
* Participants were included if they provided written informed consent, demonstrated the ability to adhere to the study protocol, and committed to attending follow-up appointments while completing the required outcome measures.

Exclusion Criteria

* Patient refusal.
* Patients above the age of 65 were eliminated to reduce confounding by age-related health concerns and to provide a more homogenous study population for more accurate treatment outcomes.
* Patients with a history of cervical spine surgery, Uncontrolled Diabetes Mellitus, Hypertension Ischemic Heart Disease, and Pregnancy
* Patients with chronic pain syndromes that may interfere with cervical radicular pain evaluation, such as fibromyalgia, rheumatoid arthritis, or hypersensitivity, will be excluded. These disorders will be evaluated during screening using a complete medical history review, physical examination, and precise diagnostic criteria to guarantee correct detection of cervical radicular discomfort.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Superior University

OTHER

Sponsor Role lead

Responsible Party

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Muhammad Naveed Babur

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ghurki trust and teaching hospital

Lahore, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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MSRSW/Batch-Fall22/765

Identifier Type: -

Identifier Source: org_study_id