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Effects of Vitamin D Supplementation on Postoperative Rehabilitation in Hip and Knee Osteoarthritis Patients

NCT ID: NCT06747559

Last Updated: 2024-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-01-01

Study Completion Date

2026-12-31

Brief Summary

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The goal of this clinical trial is to learn if vitamin D supplementation affects postoperative rehabilitation in osteoarthritis patients who underwent joint arthroplasty. The main questions it aims to answer are:

Does oral vitamin D supplementation for a period of time after joint arthroplasty affect the postoperative recovery speed in patients who have vitamin D deficiency? Does oral vitamin D supplementation after joint arthroplasty affect the long-term recovery of joint functions in patients who have vitamin D deficiency?

Participants will:

Take vitamin D oral supplement every day for 3 months. Visit the clinic in 1, 3, 6, 12 months after joint replacement surgery for checkups and tests.

Detailed Description

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Conditions

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Osteoarthritis of the Hip or Knee Joint Arthroplasty

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Vitamin D oral supplement

Using vitamin D oral supplement that has been widely used in clinic

Group Type EXPERIMENTAL

Vitamin D

Intervention Type DRUG

Vitamin D oral supplementation

No vitamin D supplementation

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Vitamin D

Vitamin D oral supplementation

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Vitamin D deficiency (blood 25-hydroxyvitamin D value \< 20ng/ml);
2. Meeting the diagnostic criteria for hip or knee osteoarthritis;
3. Planning to undergo hip or knee arthroplasty after clinical assessment;

Exclusion Criteria

1\. Having other diseases that could cause damage to the bone or cartilage structure of the hip or knee, such as trauma, joint infection, congenital joint malformation, and systemic diseases such as rheumatoid arthritis and gout.
Minimum Eligible Age

60 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yiwu Fuyuan Private Hospital

UNKNOWN

Sponsor Role collaborator

Hangzhou Xiaoshan Traditional Chinese Orthopedic Hospital

UNKNOWN

Sponsor Role collaborator

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Xiang Zhao, MD

Role: PRINCIPAL_INVESTIGATOR

2nd Affiliated Hospital, School of Medicine, Zhejiang University

Locations

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2nd Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China

Site Status

Countries

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China

Central Contacts

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Xiang Zhao, MD

Role: CONTACT

Phone: 8613750835297

Email: [email protected]

Zihao Qu, MD

Role: CONTACT

Phone: 8615700079560

Email: [email protected]

Facility Contacts

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SAHZU

Role: primary

Other Identifiers

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2024-1022

Identifier Type: -

Identifier Source: org_study_id