Postoperative Pain in Endodontic Therapy

NCT ID: NCT06741592

Last Updated: 2024-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

57 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-12

Study Completion Date

2024-12-05

Brief Summary

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The goal of this clinical trial is to evaluate the change in postoperative pain in mandibular premolar and first molar teeth with asymptomatic apical periodontitis when using EDDY and passive ultrasonic irrigation activation methods.

The null hypothesis is: "There is no difference in postoperative pain after root canal treatment between the irrigation activation systems in mandibular first molars and premolar teeth."

Detailed Description

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Conditions

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Endodontic Disease Postoperative Pain

Keywords

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EDDY Irrigation Activation Passive Ultrasonic Irrigation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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EDDY Group

The effect of the EDDY device, preferred for root canal irrigation activation, on postoperative pain formation

Group Type EXPERIMENTAL

EDDY Group

Intervention Type DEVICE

The EDDY activation of the irrigation solutions used is performed to achieve root canal disinfection and enhance antibacterial effectiveness once the root canal preparation is completed.

PUI Group

The effect of the passive ultrasonic activation method, preferred for root canal irrigation activation, on postoperative pain formation

Group Type EXPERIMENTAL

PUI Group

Intervention Type DEVICE

The passive ultrasonic activation of the irrigation solutions used is performed to achieve root canal disinfection and enhance antibacterial effectiveness once the root canal preparation is completed.

Control Group

Root canal treatment performed with conventional irrigation without the use of any activation method

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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EDDY Group

The EDDY activation of the irrigation solutions used is performed to achieve root canal disinfection and enhance antibacterial effectiveness once the root canal preparation is completed.

Intervention Type DEVICE

PUI Group

The passive ultrasonic activation of the irrigation solutions used is performed to achieve root canal disinfection and enhance antibacterial effectiveness once the root canal preparation is completed.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients aged between 18 and 55 years, medically healthy, and free from systemic diseases.
* Patients without pregnancy or breastfeeding status.
* Patients diagnosed with asymptomatic apical periodontitis confirmed through radiographic and clinical examination.
* Patients not having a regular intake of analgesic or anti-inflammatory drugs within the last 12 hours.
* Patients lacking a history of drug allergies.
* Teeth free from calcifications, resorptions, periodontal problems, incomplete root development, a history of endodontic treatment, traumatic occlusion, or severe coronal destruction.
* Teeth with a root canal curvature of 5° or less.
* Mandibular premolars and first molars.

Exclusion Criteria

* Teeth where the apical area could not be reached with a #8K file.
* Teeth with an apical diameter larger than #20K file.
* Patients with a Periapical Index (PAI) score of 1 or 2.
* Teeth having extra canals.
* Teeth requiring a second local anesthesia during treatment.
* Teeth where a file fractured within the canal during preparation.
* Vital teeth.
* Patients reporting preoperative pain.
* Teeth showing clinical symptoms such as percussion or palpation sensitivity.
* Teeth with persistent purulent discharge.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ordu University

OTHER

Sponsor Role lead

Responsible Party

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Seca MUTLU

Research Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Seca MUTLU

Role: PRINCIPAL_INVESTIGATOR

Ordu University, Faculty of Dentistry, Department of Endodontics

Locations

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Ordu University

Ordu, Karadeniz, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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ODU-MUTLU-001

Identifier Type: -

Identifier Source: org_study_id