Difference Between Monofilament Versus Multifilament Suture Material in Isthmocele Formation

NCT ID: NCT06741371

Last Updated: 2024-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-01

Study Completion Date

2025-03-01

Brief Summary

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This thesis conducts the effect of using different suture materials on the development of uterine scar niche after cesarean section.

The difference between monofilament and multifilament sutures and the special properties of each one .

The primary outcome of the study is to know which material conducts more scar niche formation .

Secondary outcomes are the extent of blood loss , the need of extra hemostatic sutures

Detailed Description

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Conditions

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Uterine Scar

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Monocryl arm

Group Type EXPERIMENTAL

Monocryl

Intervention Type PROCEDURE

Closure of the uterine scar by monofilament suture material

Vicryl arm

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Monocryl

Closure of the uterine scar by monofilament suture material

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age: 20-45 years old

* Singleton pregnancy.
* Gestational age between 37 completed weeks to 42 weeks.
* Patients undergoing elective primary caesarean section

Exclusion Criteria

* History of uterine surgery (e.g. hysterotomy, myomectomy, perforation, caesarean section). (to be able to differentiate between the recent CS scar and the old scar)

* Abnormal placental invasion (placenta previa and accrete ) ( more liable to undergo Cesarean hysterectomy)
* Uterine anomalies (e.g., septum, Mullerian anomalies or fibroids). (may be localized at the suture line and therefore affect the scar)
* Drugs intake that affects bleeding or tissue healing e.g., anti-coagulants, immunosuppressive drugs and chronic use of steroids (more than 14 days pre-operative)
* Any medical Co-morbidity (diabetes mellitus, Hypertension and Thyroid abnormalities) (more liable to affect the healing)
Minimum Eligible Age

20 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ain Shams Maternity Hospital

OTHER

Sponsor Role lead

Responsible Party

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Mohammed Essam ElDin Mohammed

Assistant lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of medicine

Cairo, Abbasya, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Mohammed Hamed, Prof

Role: CONTACT

Phone: 01226067272

Mourad Faham

Role: CONTACT

Phone: 01095830113

Email: [email protected]

Provided Documents

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Document Type: Study Protocol and Informed Consent Form

View Document

Other Identifiers

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FMASU MD333/2023

Identifier Type: -

Identifier Source: org_study_id