Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer
NCT ID: NCT06735105
Last Updated: 2024-12-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
129 participants
INTERVENTIONAL
2023-12-23
2024-12-31
Brief Summary
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This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients.
A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
DOUBLE
Study Groups
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SS-EPI-DWI T-stage of gastric cancer
No interventions assigned to this group
TSE-DWI T-stage of gastric cancer
Scanning parameter
Based on abdominal scanning, TSE-DWI,ZOOMIT DWI and EPI-DWI scans were performed, and the study was divided into two steps according to the nanomotion criteria. The first step was self-controlled, which was divided into experimental group and control group. The experimental group included TSE-DWI,ZOOMit DWI, and the control group included EPI-DWI. Then the image quality was evaluated by subjective and objective evaluation indexes. In the second step, the three DWI stages were performed separately by four diagnosticians, with an interval of 1 month, and statistical analysis was performed at the end.
ZOOM-DWI T-stage of gastric cancer
Scanning parameter
Based on abdominal scanning, TSE-DWI,ZOOMIT DWI and EPI-DWI scans were performed, and the study was divided into two steps according to the nanomotion criteria. The first step was self-controlled, which was divided into experimental group and control group. The experimental group included TSE-DWI,ZOOMit DWI, and the control group included EPI-DWI. Then the image quality was evaluated by subjective and objective evaluation indexes. In the second step, the three DWI stages were performed separately by four diagnosticians, with an interval of 1 month, and statistical analysis was performed at the end.
Interventions
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Scanning parameter
Based on abdominal scanning, TSE-DWI,ZOOMIT DWI and EPI-DWI scans were performed, and the study was divided into two steps according to the nanomotion criteria. The first step was self-controlled, which was divided into experimental group and control group. The experimental group included TSE-DWI,ZOOMit DWI, and the control group included EPI-DWI. Then the image quality was evaluated by subjective and objective evaluation indexes. In the second step, the three DWI stages were performed separately by four diagnosticians, with an interval of 1 month, and statistical analysis was performed at the end.
Eligibility Criteria
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Inclusion Criteria
2. No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image
3. No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases.
Exclusion Criteria
2. Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.
18 Years
80 Years
ALL
Yes
Sponsors
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Yunnan Cancer Hospital
OTHER
Responsible Party
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Principal Investigators
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Lianhua Ye
Role: STUDY_DIRECTOR
Ethics Committee of Yunnan Provincial Cancer Hospital
Locations
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Yunnan Cancer Hospital
Kunming, , China
Countries
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Central Contacts
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Facility Contacts
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Zhang Guojun, Professor
Role: primary
Other Identifiers
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KYLX2023-167
Identifier Type: -
Identifier Source: org_study_id