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Association Between Blood Pressure and Risk of PSCI

NCT ID: NCT06730711

Last Updated: 2024-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-01

Study Completion Date

2024-12-30

Brief Summary

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This retrospective cohort study was designed to explore the relationship between blood pressure and cognitive impairment after stroke

Detailed Description

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Patients who have been followed up for more than 3 months after stroke will be included in the study. Basic data of patients and factors that may be related to cognitive impairment will be collected, and the relationship between blood pressure and cognitive impairment after stroke will be explored by univariate regression analysis and multivariate regression analysis. Univariate logistic regression model and multivariate logistic regression model were used to explore the relationship between blood pressure level and the risk of cognitive impairment after stroke, and the effect of blood pressure level and cognitive impairment sub-line in different patients was evaluated by subgroup analysis.

Conditions

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Stroke Cognitive Decline Blood Pressure

Keywords

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stroke cognitive impairment blood pressure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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NPSCI

NPSCI was defined as a score of MMSE≥26.

No interventions assigned to this group

PSCI

The prime outcome PSCI was defined as the cognitive impairment occurred after stroke and was still present three months after stroke and cognitive impairment was defined as a score of MMSE\<26.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Patient diagnosed with stroke by CT or MRI,
2. Patients completed the MMSE scale at least once during hospitalization
3. The follow-up time was more than three months after the stroke occurred;

Exclusion Criteria

1. Patients with incomplete data, follow-up time less than three months after the stroke occurred less than 3 months,
2. Patients with pre-existing cognitive impairment before stroke according to their medical records,
3. patients failed to complete MMSE assessment because of aphasia or any other reasons,
4. Patients combined with malignant tumors, patients combined with psychiatric disorders.
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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First Affiliated Hospital of Chongqing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Dingqun Bai

Director of rehabilitation Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Dingqun Bai

Role: CONTACT

Phone: 13808380876

Email: [email protected]

Defei Chen

Role: CONTACT

Phone: +8615188017034

Email: [email protected]

Facility Contacts

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Defei Chen

Role: primary

Other Identifiers

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20241202

Identifier Type: -

Identifier Source: org_study_id