Polycystic Ovary Syndrome and Urinary Tract Stones: a BMI-Adjusted Analysis in Iraqi Women

NCT ID: NCT06729359

Last Updated: 2024-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

407 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-07-01

Study Completion Date

2024-11-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this observational case-control study is to find out the impact of PCOS as a risk factor for the presence of urinary tract stones taking into account the BMI of women aged 18-40 years consulting the gynecology and obstetrics outpatient clinic at Al-Elwiya Maternity Teaching Hospital.

The study aims to collect information from approximately 200 women with polycystic ovary syndrome and 200 volunteers who do not have PCOS.

A written consent was obtained from all the participants. The information collected included age, weight, and height. In addition, focused history and clinical examination were conducted for all patients, and for some patients, one or more additional blood tests were obtained. The additional tests included but not limited to serum levels of testosterone, dehydroepiandrosterone sulfate (DHEA-S), androstenedione, luteinizing hormone (LH), follicle-stimulating hormone (FSH), and sex hormone-binding globulin. Moreover, ultrasonography of the abdomen and pelvis was obtained for all patients as part of the diagnosis of PCOS and as screening for urinary tract stones. Also, transvaginal ultrasonography was obtained for some patients according to the individual condition as requested by the treating gynecologist. The diagnosis ofc PCOS was based on the Rotterdam criteria. (1)

The main questions the study aims to answer are:

* Is PCOS a risk factor for urinary tract stones when taking BMI into account?
* Is PCOS a risk for urinary tract stones at all?
* Is there an association between PCOS and BMI?
* Does BMI affect the presence of urinary tract stones at all and the presence of urinary tract stones when taking PCOS into account?

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

PCOS (Polycystic Ovary Syndrome) Stone, Urinary BMI Obesity Overweight Underweight

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

PCOS (Polycystic Ovary Syndrome) stone, urinary BMI Obesity Overweight Underweight

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PCOS (Polycystic Ovary Syndrome) group

includes patients diagnosed with PCOS (Polycystic Ovary Syndrome)

Ultrasonography of the abdomen and pelvis

Intervention Type DIAGNOSTIC_TEST

ultrasonography of the abdomen and pelvis using a 3.5mhz abdominal probe

Contorol group

include women of the same age group with no clinical or laboratory evidence of PCOS (Polycystic Ovary Syndrome)

Ultrasonography of the abdomen and pelvis

Intervention Type DIAGNOSTIC_TEST

ultrasonography of the abdomen and pelvis using a 3.5mhz abdominal probe

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Ultrasonography of the abdomen and pelvis

ultrasonography of the abdomen and pelvis using a 3.5mhz abdominal probe

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

tranveginal ultrasonography serum testosterone Serum dehydroepiandrosterone sulfate (DHEA-S) Serum androstenedione Serum , luteinizing hormone (LH) Serum follicle-stimulating hormone (FSH) Serum sex hormone-binding globulin

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* female
* age 18-40 years

Exclusion Criteria

* A medical or surgical condition that affects urinary tract stone formation.
* A medical or surgical condition that affects body weight or height.
* A medical or surgical condition that affects hormonal balance.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Al-Kindy College of Medicine

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Harth Mohamed Kamber

Assistant proffessor, Consultant utologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Harth Mohamed Kamber, FICMS (Uro.)

Role: STUDY_CHAIR

University of Baghdad / Alkindy College of Medicine

Weqar Akram Hussein, FICMS (Gyn.)

Role: PRINCIPAL_INVESTIGATOR

University of Baghdad / Alkindy College of Medicine

Zahraa Muhmmed Jameel Al-Sattam, FICMS (Gyn.)

Role: PRINCIPAL_INVESTIGATOR

University of Baghdad / Alkindy College of Medicine

Kamal Al-Jawdah, MBChB, MRCS, FIBMS

Role: STUDY_DIRECTOR

United Lincolnshire Teaching Hospitals NHS Trust

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Al-Elwiya Maternity Teaching Hospital

Baghdad, Alrusafa, Iraq

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Iraq

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

19 Al-KindyCM

Identifier Type: -

Identifier Source: org_study_id