Comparative Evaluation of the Effect of Different Adjunctive Air Polishing Powders in Nonsurgical Periodontal Therapy in Patients with Stage II and III Periodontitis
NCT ID: NCT06726902
Last Updated: 2024-12-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
NA
56 participants
INTERVENTIONAL
2024-03-03
2024-12-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Test Group I (GBT and SI + erythritol powder)
will receive GBT and SI with adjunctive air-polishing using Standard/ Subgingival nozzle + erythritol powder
GBT and SI with erythritol powder
Non-Surgical Periodontal treatment:
1. Guided Biofilm Therapy
* Guided supragingival and shallow subgingival (PD ≥ 4 mm) removal of biofilm and stains from all quadrants using the air-polishing device using a standard nozzle system.
* Subgingival removal of biofilm from deeper periodontal pockets (PD ≥ 6 mm) using an Air-polishing device subgingival nozzle system with erythritol powder .
2. Scaling and root planing Scaling and root planing (SRP) For the control group, conventional scaling and root planning (SRP) only.
Test Group II (GBT and SI + glycine powder)
will receive GBT and SI with adjunctive air-polishing using Standard/ Subgingival nozzle + glycine powder
GBT and SI with glycine powder
Non-Surgical Periodontal treatment:
1. Guided Biofilm Therapy • Guided supragingival and shallow subgingival (PD ≥ 4 mm) removal of biofilm and stains from all quadrants using the air-polishing device using a standard nozzle system. • Subgingival removal of biofilm from deeper periodontal pockets (PD ≥ 6 mm) using an Air-polishing device subgingival nozzle system with glycine powder.
2. Scaling and root planing Scaling and root planing (SRP) For the control group, conventional scaling and root planning (SRP) only
Test Group III (GBT and SI + Trehalose powder)
will receive GBT and SI with adjunctive air-polishing using Standard/ Subgingival nozzle + Trehalose powder
GBT and SI with trehalose powder
Non-Surgical Periodontal treatment:
1. Guided Biofilm Therapy • Guided supragingival and shallow subgingival (PD ≥ 4 mm) removal of biofilm and stains from all quadrants using the air-polishing device using a standard nozzle system. • Subgingival removal of biofilm from deeper periodontal pockets (PD ≥ 6 mm) using an Air-polishing device subgingival nozzle system with trehalose powder .
2. Scaling and root planing Scaling and root planing (SRP) For the control group, conventional scaling and root planning (SRP) only
Control Group VI (SRP and SI)
will receive conventional Scaling and Root planning (SRP) and (SI) without adjunctive air polishing powder
SRP and SI
conventional scaling and root planning (SRP) with subgingival instrumentation only will be performed
Interventions
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GBT and SI with erythritol powder
Non-Surgical Periodontal treatment:
1. Guided Biofilm Therapy
* Guided supragingival and shallow subgingival (PD ≥ 4 mm) removal of biofilm and stains from all quadrants using the air-polishing device using a standard nozzle system.
* Subgingival removal of biofilm from deeper periodontal pockets (PD ≥ 6 mm) using an Air-polishing device subgingival nozzle system with erythritol powder .
2. Scaling and root planing Scaling and root planing (SRP) For the control group, conventional scaling and root planning (SRP) only.
GBT and SI with glycine powder
Non-Surgical Periodontal treatment:
1. Guided Biofilm Therapy • Guided supragingival and shallow subgingival (PD ≥ 4 mm) removal of biofilm and stains from all quadrants using the air-polishing device using a standard nozzle system. • Subgingival removal of biofilm from deeper periodontal pockets (PD ≥ 6 mm) using an Air-polishing device subgingival nozzle system with glycine powder.
2. Scaling and root planing Scaling and root planing (SRP) For the control group, conventional scaling and root planning (SRP) only
GBT and SI with trehalose powder
Non-Surgical Periodontal treatment:
1. Guided Biofilm Therapy • Guided supragingival and shallow subgingival (PD ≥ 4 mm) removal of biofilm and stains from all quadrants using the air-polishing device using a standard nozzle system. • Subgingival removal of biofilm from deeper periodontal pockets (PD ≥ 6 mm) using an Air-polishing device subgingival nozzle system with trehalose powder .
2. Scaling and root planing Scaling and root planing (SRP) For the control group, conventional scaling and root planning (SRP) only
SRP and SI
conventional scaling and root planning (SRP) with subgingival instrumentation only will be performed
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
2. Stage II and III (moderate to severe) periodontitis, having at least 16 teeth with the need for SI
3. Interproximal plaque index (API) ≤ 35%; patients with Good oral hygiene.
4. No history of systemic disease that may influence periodontal disease
Exclusion Criteria
2. Smokers with more than seven cigarettes per day
3. Patients that had a treatment with antibiotics within six months before the study
4. Need for periodontal surgery or adjunctive antibiotic treatment to the SI
5. Patients who had any periodontal treatment during the last year before the study.
6. Patients with known systemic or autoimmune disease.
30 Years
65 Years
ALL
No
Sponsors
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Diana Ibrahim
OTHER
Responsible Party
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Diana Ibrahim
Periodontology MSc. Candidate
Principal Investigators
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Rania Abdelaziz Fahmy, PhD
Role: STUDY_DIRECTOR
Alexandria University
Locations
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Faculty of Dentistry, Alexandria University
Alexandria, , Egypt
Countries
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Other Identifiers
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IORG 0008839-0854-01/2024
Identifier Type: -
Identifier Source: org_study_id