Digital Health and Exercise for Autonomous Longevity Program

NCT ID: NCT06722976

Last Updated: 2024-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-05

Study Completion Date

2025-07-01

Brief Summary

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Digital HEAL (Health and Exercise for Autonomous Longevity) is a multicomponent training program (combining concurrent training with cognitive stimulation) designed to promote physical fitness and cognitive function in older adults. This program merges a community-based approach with a scientific research project aimed at comparing the effects of in-person and online concurrent training on cognitive function and functional capacity in this population.

The program is structured into three phases: (1) Initial Assessment; (2) Multicomponent Training Sessions; (3) Final Assessment.

1. Initial Assessment The initial assessment will consist of physical fitness tests (approximately 1 hour) and Neuropsychological Evaluation tests (approximately 1.5 hours).
2. Multicomponent Training Sessions The multicomponent training sessions will last for 3 months, with a frequency of two sessions per week, each lasting 50 minutes, conducted in person at the institution.
3. Final Assessment The final assessment will be identical to the initial assessment, comprising physical fitness tests (approximately 1 hour) and Neuropsychological Evaluation tests (approximately 1.5 hours).

Expected Benefits The anticipated benefits for participants include significant improvements in physical fitness, with a particular emphasis on strength, balance, and motor autonomy, which play an essential role in fall prevention. Additionally, cognitive abilities such as orientation, memory, and brain plasticity are expected to improve. The program also aims to promote social interaction, reducing social isolation among older adults. Furthermore, the program will support participants\' maintenance within the institution, which helps preserve their routine and address mobility and accessibility limitations. This intervention will also help reduce costs and time for the institution.

Potential Risks The risks associated with participation in the program are similar to those inherent in any physical activity. However, the equipment and environment (floor type, lighting, temperature) are evaluated to ensure suitability for safe exercise at any age. The exercises are supervised by a qualified professional who takes special care to minimize exercise-related risks.

Detailed Description

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Digital HEAL (Health and Exercise for Autonomous Longevity) is a multicomponent training program (combining concurrent training with cognitive stimulation) designed to promote physical fitness and cognitive function in older adults. This program merges a community-based approach with a scientific research project aimed at comparing the effects of in-person and online concurrent training on cognitive function and functional capacity in this population.

The program is developed and implemented by the Department of Sports Sciences, the Faculty of Health Sciences, and the Department of Psychology and Education of the University of Beira Interior (UBI), in collaboration with the University of Turin. The principal investigator is Ricardo André Alves Bispo Madeira.

The program is structured into three phases: (1) Initial Assessment; (2) Multicomponent Training Sessions; (3) Final Assessment.

1. Initial Assessment The initial assessment will consist of physical fitness tests (approximately 1 hour) and Neuropsychological Evaluation tests (approximately 1.5 hours).
2. Multicomponent Training Sessions The multicomponent training sessions will last for 3 months, with a frequency of two sessions per week, each lasting 50 minutes, conducted in person at the institution.
3. Final Assessment The final assessment will be identical to the initial assessment, comprising physical fitness tests (approximately 1 hour) and Neuropsychological Evaluation tests (approximately 1.5 hours).

Expected Benefits The anticipated benefits for participants include significant improvements in physical fitness, with a particular emphasis on strength, balance, and motor autonomy, which play an essential role in fall prevention. Additionally, cognitive abilities such as orientation, memory, and brain plasticity are expected to improve. The program also aims to promote social interaction, reducing social isolation among older adults. Furthermore, the program will support participants\' maintenance within the institution, which helps preserve their routine and address mobility and accessibility limitations. This intervention will also help reduce costs and time for the institution.

Potential Risks The risks associated with participation in the program are similar to those inherent in any physical activity. However, the equipment and environment (floor type, lighting, temperature) are evaluated to ensure suitability for safe exercise at any age. The exercises are supervised by a qualified professional who takes special care to minimize exercise-related risks.

Voluntary Participation and Confidentiality Participation in the program is entirely voluntary, and participants can withdraw at any time without any consequences. Confidentiality is guaranteed, with only the principal investigator, Ricardo André Alves Bispo Madeira, having access to personal data, which will always be coded and not disclosed. The collected data will be used strictly for academic purposes, with no commercial interests. Upon request, individual data can be provided to each participant, improving the assessment of their current condition.

Research Team

The team of researchers involved includes:

Dr. Maria da Assunção Vaz Patto (Associate Professor at the Faculty of Health Sciences, UBI, and researcher at the Health Sciences Research Center - CICS-UBI) Dr. Maria Dulce Leal Esteves (Lecturer in the Department of Sports Sciences and researcher at the Research Center for Sport, Health, and Human Development - CIDESD) Dr. Nuno Filipe Cardoso Pinto (Adjunct Assistant Professor at the Faculty of Health Sciences, UBI, and researcher at CICS-UBI) Ricardo André Alves Bispo Madeira (Ph.D. student in Sports Sciences)

Principal Investigator Signature

By signing this document, I confirm, on behalf of the research team, that I have conveyed all the information contained herein, explained it, and answered all questions and concerns raised by the participant and their family members.

Conditions

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Mild Cognitive Impairment (MCI) Older People

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Investigators

Study Groups

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face-to-face

The program is organized into three phases: (1) Initial assessment; (2) Multicomponent training sessions; (3) Final assessment.

1. The initial assessment will consist of physical fitness tests (lasting around 1 hour) and Neuropsychological Assessment tests (lasting around 1.5 hours).
2. The multicomponent training sessions will last 3 months, twice a week, 50 minutes each session, held in person at the institution.
3. The final assessment will be the same as the initial assessment (physical fitness tests (about 1 hour) and Neuropsychological Assessment tests (about 1.5 hours).

Group Type EXPERIMENTAL

Multicomponent exercise programs

Intervention Type OTHER

The program is organized into three phases: (1) Initial assessment; (2) Multicomponent training sessions; (3) Final assessment.

1. The initial assessment will consist of physical fitness tests (lasting around 1 hour) and Neuropsychological Assessment tests (lasting around 1.5 hours).
2. The multicomponent training sessions will last 3 months, twice a week, 50 minutes each session.
3. The final assessment will be the same as the initial assessment (physical fitness tests (about 1 hour) and Neuropsychological Assessment tests (about 1.5 hours).

Synchronous distance (video call)

The program is organized into three phases: (1) Initial assessment; (2) Multicomponent training sessions; (3) Final assessment.

1. The initial assessment will consist of physical fitness tests (lasting around 1 hour) and Neuropsychological Assessment tests (lasting around 1.5 hours).
2. The multicomponent training sessions will last 3 months, twice a week, 50 minutes each, carried out by video call.
3. The final assessment will be the same as the initial assessment (physical fitness tests (about 1 hour) and Neuropsychological Assessment tests (about 1.5 hours).

Group Type EXPERIMENTAL

Multicomponent exercise programs

Intervention Type OTHER

The program is organized into three phases: (1) Initial assessment; (2) Multicomponent training sessions; (3) Final assessment.

1. The initial assessment will consist of physical fitness tests (lasting around 1 hour) and Neuropsychological Assessment tests (lasting around 1.5 hours).
2. The multicomponent training sessions will last 3 months, twice a week, 50 minutes each session.
3. The final assessment will be the same as the initial assessment (physical fitness tests (about 1 hour) and Neuropsychological Assessment tests (about 1.5 hours).

Control group

In the control group, the participants take part in the training sessions, and the program is organized into two phases: (1) Initial assessment; (2) Final assessment.

1. The initial assessment will consist of physical fitness tests (lasting around 1 hour) and Neuropsychological Assessment tests (lasting around 1.5 hours).
2. The final assessment will be the same as the initial assessment (physical fitness tests (duration approx. 1h) and Neuropsychological Assessment tests (duration approx. 1.5h).

After completing the assessment, participants will be given the opportunity to do the exercise sessions.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Multicomponent exercise programs

The program is organized into three phases: (1) Initial assessment; (2) Multicomponent training sessions; (3) Final assessment.

1. The initial assessment will consist of physical fitness tests (lasting around 1 hour) and Neuropsychological Assessment tests (lasting around 1.5 hours).
2. The multicomponent training sessions will last 3 months, twice a week, 50 minutes each session.
3. The final assessment will be the same as the initial assessment (physical fitness tests (about 1 hour) and Neuropsychological Assessment tests (about 1.5 hours).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Male and female participants aged ≥ 65 years.
* A score of ≥ 3 on the Short Physical Performance Battery (SPPB).
* Willingness to participate in the training programs and collaborate with the research team.

Ability to provide informed consent, either oral or written.

Exclusion Criteria

* A score of ≤ 3 on the Short Physical Performance Battery (SPPB).
* Presence of severe comorbidities that would negatively impact participation in the training program.
* Presence of color blindness.
* Diagnosis of severe dementia or severe impairment across multiple dimensions of cognition, which would prevent participation in the training program.
* History of surgeries or fractures within the last 6 months.

These criteria ensure that participants are suitable for the program and capable of engaging in the training sessions effectively.
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Beira Interior

OTHER

Sponsor Role lead

Responsible Party

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Ricardo Madeira

PhD Student

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dulce Esteves, PhD

Role: STUDY_DIRECTOR

University of Beira Interior

Locations

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Departement of Sports Science

Covilha, Covilhã, Portugal

Site Status

Countries

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Portugal

References

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Hu JP, Guo YH, Wang F, Zhao XP, Zhang QH, Song QH. Exercise improves cognitive function in aging patients. Int J Clin Exp Med. 2014 Oct 15;7(10):3144-9. eCollection 2014.

Reference Type BACKGROUND
PMID: 25419345 (View on PubMed)

Janson P, Willeke K, Zaibert L, Budnick A, Berghofer A, Kittel-Schneider S, Heuschmann PU, Zapf A, Wildner M, Stupp C, Keil T. Mortality, Morbidity and Health-Related Outcomes in Informal Caregivers Compared to Non-Caregivers: A Systematic Review. Int J Environ Res Public Health. 2022 May 11;19(10):5864. doi: 10.3390/ijerph19105864.

Reference Type BACKGROUND
PMID: 35627399 (View on PubMed)

Tokovska M, Nour MM, Sorensen A, Smaland Goth U. Informal caregivers and psychosocial support: Analysis of European Dementia Policy documents. J Public Health Res. 2021 Sep 27;11(1):2416. doi: 10.4081/jphr.2021.2416.

Reference Type BACKGROUND
PMID: 34579521 (View on PubMed)

Other Identifiers

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PRT/BD/154440/2022

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

CE-UBI-Pj-2023-064-ID1994

Identifier Type: -

Identifier Source: org_study_id