School-based Program for the Prevention of Rheumatic Heart Disease in Endemic Regions
NCT ID: NCT06720272
Last Updated: 2024-12-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
6000 participants
INTERVENTIONAL
2024-12-15
2028-02-29
Brief Summary
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We conduct a stepped wedge cluster randomized trial in randomly selected schools in Nepal and Zambia.
The intervention will be delivered at the level of the school and consists in the introduction of a dedicated school-nurse program providing health care through education about RHD, assessment, intervention, and follow-up of GABHS pharyngitis, and facilitation of secondary antibiotic prophylaxis for children with RHD.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
SEQUENTIAL
PREVENTION
SINGLE
Study Groups
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School nurse program
The experimental intervention consists in a school nurse program providing integrated health care through diagnosis, intervention, and follow-up of group A beta-hemolytic streptococcal pharyngitis, and facilitation of secondary antibiotic prophylaxis for children with rheumatic heart disease.
School nurse program
The intervention consists in the introduction of a school-nurse program providing health care through education about rheumatic heart disease, assessment, intervention, and follow-up of group A beta-hemolytic streptococcal pharyngitis, and facilitation of secondary antibiotic prophylaxis for children with rheumatic heart disease.
Standard of care
No school nurse prorgam.
No interventions assigned to this group
Interventions
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School nurse program
The intervention consists in the introduction of a school-nurse program providing health care through education about rheumatic heart disease, assessment, intervention, and follow-up of group A beta-hemolytic streptococcal pharyngitis, and facilitation of secondary antibiotic prophylaxis for children with rheumatic heart disease.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Children not attending one of the selected schools
5 Years
16 Years
ALL
Yes
Sponsors
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Centre for Infectious Disease Research in Zambia (CIDRZ)
UNKNOWN
National Academy of Medical Sciences, Nepal
OTHER_GOV
University of Oxford
OTHER
Thomas Pilgrim
OTHER
Responsible Party
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Thomas Pilgrim
MD, MSc
Central Contacts
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Thomas Pilgrim Bern University Hospital, Bern, Switzerland
Role: CONTACT
Phone: +41 31 632 08 27
Other Identifiers
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PREVENT
Identifier Type: -
Identifier Source: org_study_id