Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-16

Study Completion Date

2026-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities.

BLAAC PD is happening at research centers around the United States. The study is part of the Global Parkinson's Genetics Program (GP2). GP2 is a research project working to transform understanding of the genetics of Parkinson's disease and make that knowledge globally relevant.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Research studies have found connections between genes and Parkinson's disease (PD). But those results have mostly come from studies with non-Black or African American volunteers. BLAAC PD aims to learn more about gene changes that may cause Parkinson's in Black and African American people. Study volunteers at sites across the United States will attend one visit and will give either a blood or saliva sample, complete a smell test, and may be asked to complete a physical exam. This new data could lead to future Parkinson's tests and treatments for Black and African American people and it may help better understand disease in other groups, too.

This pioneering initiative will fill a gap of knowledge about PD in Black and African American people.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Parkinson Disease

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

genetics racial health disparities

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Participants with Parkinson's Disease

Data collected from these participants include demographic information and family health history. Participants may also complete a physical exam. Participants also complete a smell test and contribute a blood or saliva sample for genetic analyses.

No interventions assigned to this group

Control Participants

Data collected from these participants include demographic information and family health history. Participants also complete a smell test and contribute a blood or saliva sample for genetic analyses.

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Ability to provide informed consent
* Age 18 years or older
* Self-identify as Black or African American

* Ability to provide informed consent
* Age 18 years or older
* Self-identify as Black or African American
* Meet the Movement Disorder Society's clinical diagnostic criteria for Parkinson's disease

Exclusion Criteria

* Diagnosis of Parkinson's Disease and/or neurological condition
* Familial history of PD and/or neurodegenerative or psychiatric conditions
* Unknown family history of PD and/or neurodegenerative or psychiatric conditions
* Any conditions that, in the investigator's opinion, preclude the individual's ability to carry out study activities
* If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection

\- If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Andrew Singleton, PhD

Role: PRINCIPAL_INVESTIGATOR

National Institutes of Health (NIH)

Reach out to these primary contacts for questions about participation or study logistics.

Naomi Louie, MPH RDN

Role: CONTACT

Phone: 212-509-0995

Email: [email protected]

J Solle, MBA

Identifier Source: org_study_id

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

Study Results

Basic Information

Brief Summary

Detailed Description

Conditions

Keywords

Study Design

Study Groups

Participants with Parkinson's Disease

Control Participants

Eligibility Criteria

Inclusion Criteria

Exclusion Criteria

Sponsors

National Institutes of Health (NIH)

University of Chicago

University of Alabama at Birmingham

Rush University

Washington University School of Medicine

Medical University of South Carolina

University Hospitals Cleveland Medical Center

Louisiana State University Health Sciences Center Shreveport

University of Florida

University of Maryland

The University of Texas Health Science Center, Houston

Ochsner Health System

Michael J. Fox Foundation for Parkinson's Research

Responsible Party

Principal Investigators

Andrew Singleton, PhD

Locations

University of Alabama at Birmingham

University of Florida

Rush University

University of Chicago

Ochsner Clinic Foundation

Louisiana State University Health Sciences Center Shreveport

University of Maryland

Kaiser Permanente Midatlantic States

Washington University in St. Louis

University Hospitals Cleveland Medical Center

Medical University of South Carolina

University of Texas Health Science Center, Houston

Countries

Central Contacts

Naomi Louie, MPH RDN

J Solle, MBA

Facility Contacts

Joseph Richardson

Lauren Ruffrage

Marissa Dean, MD

David Standaert, MD, PhD

Randy Foli

Kyle Rizer

Ashley Rawls, MD

Lauren Fanty, MD

Tracy Tholanikunnel, MD

Jacqueline Vanegas

Deborah Hall, MD

Crystal Mercado

Tao Xie, MD, PhD

Mahesh Padmananban, MD

Dominique Thomas

Julia Staisch, MD

Sarah Breaux, MD

Mackenzie Williams

Elizabeth Disbrow, PhD

Christina Griffin

Rebecca Weimer

Lisa Shulman, MD

Rainer von Coelln, MD

Coordinator

Scott Norris, MD

Erin Foster, PhD, OTD-L

Ashley Hawkins

Camilla Kilbane, MD

Mohamed Elkasaby, MD

Lisa Heidelberg

Vanessa Hinson, MD