Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
NCT ID: NCT06716892
Last Updated: 2024-12-04
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
40 participants
OBSERVATIONAL
2024-11-28
2025-07-31
Brief Summary
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Healthy volunteers as well as patients with a diagnosed head and neck cancer entity will be recruited. Both cohorts will then be scanned on different body areas (most common tissue sites used for reconstructive surgery on the back, arms and legs) to assess differences in muscle oxygenation between the healthy and tumor patient cohort using MSOT.
The hypothesis of the study is, that patients with diagnosed head and neck cancer entities are prone to compromised tissue perfusion due to a high prevalence of smoking within the head neck tumor patient cohort and therefore perfusion restirciting diseases e.g. peripheral arterial occlusive disease (PAOD).
Detailed Description
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Conditions
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Keywords
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Healthy
Healthy adult volunteers. Exclusion criteria: Chronical abuse of alcohol and nicotine, pregnancy and breastfeeding, ink / tattoo in the areas of interest (upper back, distal forearm, upper and lower leg)
Multispectral Optoacoustic Tomography (MSOT)
Non-invasive transcutaneous MSOT imaging of muscle and subcutaneos regions.
Head and neck cancer patients.
Patients with histopathological diagnosed head and neck cancer.
Multispectral Optoacoustic Tomography (MSOT)
Non-invasive transcutaneous MSOT imaging of muscle and subcutaneos regions.
Interventions
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Multispectral Optoacoustic Tomography (MSOT)
Non-invasive transcutaneous MSOT imaging of muscle and subcutaneos regions.
Eligibility Criteria
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Inclusion Criteria
* Cohort 2: Healthy adults.
Exclusion Criteria
* ink / tattoo in the areas of interest (upper back, distal forearm, upper and lower leg)
* missing consent form
* Cohort 2: Chronical abuse of alcohol and nicotine.
18 Years
ALL
Yes
Sponsors
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University of Erlangen-Nürnberg Medical School
OTHER
Responsible Party
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Locations
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University Hospital Erlangen
Erlangen, Bavaria, Germany
Countries
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Central Contacts
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Facility Contacts
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Felix Wachter
Role: primary
Jonas Wolf, Dr. med.
Role: backup
Other Identifiers
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24-335-B
Identifier Type: -
Identifier Source: org_study_id