Effects of DL-endopeptidase Producing Probiotics on Human Intestinal NOD2 Ligands and Related Functions

NCT ID: NCT06716047

Last Updated: 2026-01-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

EARLY_PHASE1

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-05

Study Completion Date

2025-12-30

Brief Summary

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We have discovered a type of probiotic that can target activating intestinal NOD2, which is related to a series of human health issues.

Detailed Description

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This trial requires the subjects to take probiotics for a certain period of time, and we will collect blood, stool and questionnaires for subsequent testing, efficacy evaluation and safety evaluation.

Conditions

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Microecological Therapy Probiotic Intervention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants

Study Groups

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placebo

resistant dextrin

Group Type PLACEBO_COMPARATOR

Oral administration

Intervention Type OTHER

Take it directly

probiotics

lactobacillus

Group Type EXPERIMENTAL

Oral administration

Intervention Type OTHER

Take it directly

Interventions

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Oral administration

Take it directly

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Tend to participate the trial
* Willing to provide written informed consent

Exclusion Criteria

* Recent use of probiotics, antibiotics, laxatives, or gastrointestinal ulcer medications within the past month.
* Gastrointestinal symptoms (e.g., constipation, abdominal pain, diarrhea, melena, hematochezia) in the past month.
* Other conditions considered by researchers for exclusion
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Zhujiang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Industrial Avenue 253, canton

Guangzhou, Guangzhou, China

Site Status

Countries

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China

Other Identifiers

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ZhujiangHZD

Identifier Type: -

Identifier Source: org_study_id

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