Correlation Between Serum Adiponectin And Resistin Levels And Degree of Hepatic Fibrosis in MASlD With type2 Diabetes Mellitus

NCT ID: NCT06715189

Last Updated: 2024-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-12-01

Study Completion Date

2025-12-30

Brief Summary

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Metabolic dysfunction asociated steatotic liver disease prevalence is 25%world wide diabetic patients have a risk for MASLD then have hepatic fibrosis so we study correlation Between Serum Adiponectin And Resistin Levels And Degree of Hepatic fibrosis In Metabolic dysfunction asociated steatotic liver disease in patients with type2 Diabetes Mellitus

Detailed Description

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Conditions

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Hepatic Fibrosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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MASLD patients with hepatic fibrosis

MASLD with hepatic fibrosis with type 2 diabetes mellitus

serum Adiponectine and Resistin

Intervention Type DIAGNOSTIC_TEST

corrolation between serum adiponectin and Resistin levels and degree of hepatic fibrosis

fibroscan

Intervention Type DIAGNOSTIC_TEST

hepatic fibrosis detection in type 2 diabetes mellutis

MASLD without hepatic fibrosis

MASLD with out hepatic fibrosis with type 2 diabetes mellutis

serum Adiponectine and Resistin

Intervention Type DIAGNOSTIC_TEST

corrolation between serum adiponectin and Resistin levels and degree of hepatic fibrosis

fibroscan

Intervention Type DIAGNOSTIC_TEST

hepatic fibrosis detection in type 2 diabetes mellutis

Interventions

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serum Adiponectine and Resistin

corrolation between serum adiponectin and Resistin levels and degree of hepatic fibrosis

Intervention Type DIAGNOSTIC_TEST

fibroscan

hepatic fibrosis detection in type 2 diabetes mellutis

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* patients of both sex who have type2 Diabetes Mellitus for less than five years

Exclusion Criteria

\-
Minimum Eligible Age

30 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Elzahraa Kadry Mohamed

Teaching assistant fellow At sohag teaching hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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ELZAHRAA K Mohammed, spcialist

Role: CONTACT

01064954825

usama M Abdelaal, professor

Role: CONTACT

01065962094

References

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Chan WK, Chuah KH, Rajaram RB, Lim LL, Ratnasingam J, Vethakkan SR. Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A State-of-the-Art Review. J Obes Metab Syndr. 2023 Sep 30;32(3):197-213. doi: 10.7570/jomes23052. Epub 2023 Sep 13.

Reference Type BACKGROUND
PMID: 37700494 (View on PubMed)

Marchesini G, Vettor R, Pinzani M. MASLD emerging from the fog of fatty liver. J Hepatol. 2024 Feb;80(2):178-180. doi: 10.1016/j.jhep.2023.10.011. Epub 2023 Nov 30. No abstract available.

Reference Type BACKGROUND
PMID: 38278621 (View on PubMed)

Teng ML, Ng CH, Huang DQ, Chan KE, Tan DJ, Lim WH, Yang JD, Tan E, Muthiah MD. Global incidence and prevalence of nonalcoholic fatty liver disease. Clin Mol Hepatol. 2023 Feb;29(Suppl):S32-S42. doi: 10.3350/cmh.2022.0365. Epub 2022 Dec 14.

Reference Type BACKGROUND
PMID: 36517002 (View on PubMed)

Estes C, Razavi H, Loomba R, Younossi Z, Sanyal AJ. Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease. Hepatology. 2018 Jan;67(1):123-133. doi: 10.1002/hep.29466. Epub 2017 Dec 1.

Reference Type BACKGROUND
PMID: 28802062 (View on PubMed)

Other Identifiers

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Soh-Med-24-11--5MD

Identifier Type: -

Identifier Source: org_study_id