PERMA-Based Intervention on Negative Emotions, Adherence, and Complications in Postoperative Glioma Patients

NCT ID: NCT06713395

Last Updated: 2024-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

124 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-10

Study Completion Date

2024-02-25

Brief Summary

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The goal of this clinical trial is to evaluate whether a PERMA-based integrated psychological intervention can reduce negative emotions, enhance treatment adherence, and decrease the risk of complications in postoperative glioma patients.

The main questions it aims to answer are:

Can the PERMA-based psychological intervention significantly improve anxiety and depression scores in postoperative glioma patients? Does the intervention improve treatment adherence, reduce complications, and enhance quality of life compared to standard care? Researchers will compare an observation group receiving the PERMA-based psychological intervention to a control group receiving standard postoperative care to see if the intervention improves patient outcomes.

Participants will:

Receive either standard postoperative care (control group) or PERMA-based psychological intervention for one month (observation group).

Be assessed on:

Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS). Treatment Adherence Scale and Complication Record Form. Quality of Life Scale. Be followed for complications using Kaplan-Meier survival analysis.

Detailed Description

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Conditions

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Glioma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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control group

The control group was provided with standard postoperative care

Group Type OTHER

The control group received standard postoperative care

Intervention Type OTHER

standard postoperative care

observation group

The observation group received an additional PERMA-based integrated psychological intervention

Group Type OTHER

PERMA

Intervention Type OTHER

1. Establishment of the Integrated Psychological Intervention Team:

The team consisted of 2 primary nurses, 4 specialist nurses, 1 psychologist, 2 physicians at the attending level or higher, and 2 researchers.

Team Responsibilities: The primary and specialist nurses were responsible for implementing the intervention protocol. The physicians handled any adverse reactions experienced by the patients. The researchers were in charge of developing the intervention protocol and collecting data. All team members were required to undergo specialized training from the psychologist and pass an assessment before initiating the intervention.
2. Protocol Development:

The intervention protocol, including specific content, team responsibilities, implementation process, and responses to adverse events, was carefully developed in written form by the researchers. The protocol was discussed and approved by all team members before implementation.
3. Protocol Implementation:

Emotional Support Intervention:

Interventions

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The control group received standard postoperative care

standard postoperative care

Intervention Type OTHER

PERMA

1. Establishment of the Integrated Psychological Intervention Team:

The team consisted of 2 primary nurses, 4 specialist nurses, 1 psychologist, 2 physicians at the attending level or higher, and 2 researchers.

Team Responsibilities: The primary and specialist nurses were responsible for implementing the intervention protocol. The physicians handled any adverse reactions experienced by the patients. The researchers were in charge of developing the intervention protocol and collecting data. All team members were required to undergo specialized training from the psychologist and pass an assessment before initiating the intervention.
2. Protocol Development:

The intervention protocol, including specific content, team responsibilities, implementation process, and responses to adverse events, was carefully developed in written form by the researchers. The protocol was discussed and approved by all team members before implementation.
3. Protocol Implementation:

Emotional Support Intervention:

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ①Meeting the relevant diagnostic criteria from the 5th edition of the World Health Organization Classification of Central Nervous System (CNS) Tumors, and confirmed through postoperative pathological examination;
* ②Underwent surgical treatment;
* ③Clear consciousness, with good communication ability, and capable of cooperating with healthcare personnel to complete the study;
* ④Complete clinical data.

Exclusion Criteria

* ①Concurrent diagnosis of other malignant tumors;
* ②Coexisting cognitive impairment or other psychiatric disorders;
* ③Combined liver or kidney dysfunction, immune system disorders, or other severe diseases;
* ④Presence of infectious diseases;
* ⑤Pregnant or breastfeeding women.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Affiliated Brain Hospital of Nanjing Medical University

OTHER_GOV

Sponsor Role collaborator

Yang Huang

OTHER_GOV

Sponsor Role lead

Responsible Party

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Yang Huang

The Affiliated Brain Hospital of Nanjing Medical University

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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The Affiliated Brain Hospital of Nanjing Medical University

Nanjing, Jiangsu, China

Site Status

Countries

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China

Other Identifiers

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2020-KY091-01

Identifier Type: -

Identifier Source: org_study_id