Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
102 participants
OBSERVATIONAL
2024-12-31
2025-10-31
Brief Summary
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Detailed Description
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Gait and balance are the product of successful integration of various posture control mechanisms and locomotion.
There are two basic phases in the full cycle of the step Stance phase Swing phase Slow gait speeds are associated with both cognitive decline and greater risk of dementia So, our aim of this work is to study the existence and pattern of gait balance impairment in patients with different types of dementia and comparison with healthy elderly people.
Conditions
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Study Design
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CASE_CONTROL
OTHER
Study Groups
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Cohort 1 (Dementia)
The group that will contain the diseased participants (Dementic patients able to walk and perform gait analysis)
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
30 Years
80 Years
ALL
Yes
Sponsors
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Assiut University
OTHER
Responsible Party
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Hanan Samwaeil Attia Salib
Resident doctor
Principal Investigators
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Anwer M Ali, Professor
Role: STUDY_DIRECTOR
Department of Neuropsychiatry in Assuit University Tertiary Hospital
Central Contacts
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References
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Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, Brayne C, Burns A, Cohen-Mansfield J, Cooper C, Costafreda SG, Dias A, Fox N, Gitlin LN, Howard R, Kales HC, Kivimaki M, Larson EB, Ogunniyi A, Orgeta V, Ritchie K, Rockwood K, Sampson EL, Samus Q, Schneider LS, Selbaek G, Teri L, Mukadam N. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet. 2020 Aug 8;396(10248):413-446. doi: 10.1016/S0140-6736(20)30367-6. Epub 2020 Jul 30. No abstract available.
Jack CR Jr, Knopman DS, Jagust WJ, Petersen RC, Weiner MW, Aisen PS, Shaw LM, Vemuri P, Wiste HJ, Weigand SD, Lesnick TG, Pankratz VS, Donohue MC, Trojanowski JQ. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol. 2013 Feb;12(2):207-16. doi: 10.1016/S1474-4422(12)70291-0.
Borson S, Raskind MA. Clinical features and pharmacologic treatment of behavioral symptoms of Alzheimer's disease. Neurology. 1997 May;48(5 Suppl 6):S17-24. doi: 10.1212/wnl.48.5_suppl_6.17s.
Rodriguez Garcia PL, Rodriguez Garcia D. Diagnosis of vascular cognitive impairment and its main categories. Neurologia. 2015 May;30(4):223-39. doi: 10.1016/j.nrl.2011.12.014. Epub 2012 Jun 26. English, Spanish.
Dicharry J. Kinematics and kinetics of gait: from lab to clinic. Clin Sports Med. 2010 Jul;29(3):347-64. doi: 10.1016/j.csm.2010.03.013.
Jayakody O, Breslin M, Srikanth VK, Callisaya ML. Gait Characteristics and Cognitive Decline: A Longitudinal Population-Based Study. J Alzheimers Dis. 2019;71(s1):S5-S14. doi: 10.3233/JAD-181157.
Verghese J, Wang C, Lipton RB, Holtzer R, Xue X. Quantitative gait dysfunction and risk of cognitive decline and dementia. J Neurol Neurosurg Psychiatry. 2007 Sep;78(9):929-35. doi: 10.1136/jnnp.2006.106914. Epub 2007 Jan 19.
Moran C, Beare R, Phan TG, Bruce DG, Callisaya ML, Srikanth V; Alzheimer's Disease Neuroimaging Initiative (ADNI). Type 2 diabetes mellitus and biomarkers of neurodegeneration. Neurology. 2015 Sep 29;85(13):1123-30. doi: 10.1212/WNL.0000000000001982. Epub 2015 Sep 2.
Brach JS, Talkowski JB, Strotmeyer ES, Newman AB. Diabetes mellitus and gait dysfunction: possible explanatory factors. Phys Ther. 2008 Nov;88(11):1365-74. doi: 10.2522/ptj.20080016. Epub 2008 Sep 18.
Blumen HM, Brown LL, Habeck C, Allali G, Ayers E, Beauchet O, Callisaya M, Lipton RB, Mathuranath PS, Phan TG, Pradeep Kumar VG, Srikanth V, Verghese J. Gray matter volume covariance patterns associated with gait speed in older adults: a multi-cohort MRI study. Brain Imaging Behav. 2019 Apr;13(2):446-460. doi: 10.1007/s11682-018-9871-7.
Jayakody O, Breslin M, Beare R, Srikanth VK, Blumen HM, Callisaya ML. The Associations Between Grey Matter Volume Covariance Patterns and Gait Variability-The Tasmanian Study of Cognition and Gait. Brain Topogr. 2021 Jul;34(4):478-488. doi: 10.1007/s10548-021-00841-5. Epub 2021 Apr 29.
Rosano C, Studenski SA, Aizenstein HJ, Boudreau RM, Longstreth WT Jr, Newman AB. Slower gait, slower information processing and smaller prefrontal area in older adults. Age Ageing. 2012 Jan;41(1):58-64. doi: 10.1093/ageing/afr113. Epub 2011 Sep 28.
Srikanth V, Beare R, Blizzard L, Phan T, Stapleton J, Chen J, Callisaya M, Martin K, Reutens D. Cerebral white matter lesions, gait, and the risk of incident falls: a prospective population-based study. Stroke. 2009 Jan;40(1):175-80. doi: 10.1161/STROKEAHA.108.524355. Epub 2008 Oct 16.
Del Campo N, Payoux P, Djilali A, Delrieu J, Hoogendijk EO, Rolland Y, Cesari M, Weiner MW, Andrieu S, Vellas B; MAPT/DSA Study Group. Relationship of regional brain beta-amyloid to gait speed. Neurology. 2016 Jan 5;86(1):36-43. doi: 10.1212/WNL.0000000000002235. Epub 2015 Dec 7.
Dias EN, da Silva JV, Pais-Ribeiro JL, Martins T. Validation of the advanced activities of daily living scale. Geriatr Nurs. 2019 Jan-Feb;40(1):7-12. doi: 10.1016/j.gerinurse.2018.05.008. Epub 2018 Jun 13.
Rahman TT, El Gaafary MM. Montreal Cognitive Assessment Arabic version: reliability and validity prevalence of mild cognitive impairment among elderly attending geriatric clubs in Cairo. Geriatr Gerontol Int. 2009 Mar;9(1):54-61. doi: 10.1111/j.1447-0594.2008.00509.x.
Berg KO, Wood-Dauphinee SL, Williams JI, Maki B. Measuring balance in the elderly: validation of an instrument. Can J Public Health. 1992 Jul-Aug;83 Suppl 2:S7-11.
Other Identifiers
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Gait analysis in dementia
Identifier Type: -
Identifier Source: org_study_id