Effect of Quranic Recitation and Classical Music on Pain Intensity and Interleukin-6 Levels After Lower Limb Orthopedic Surgery with Intrathecal Anesthesia

NCT ID: NCT06713044

Last Updated: 2024-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-09-01

Study Completion Date

2025-03-30

Brief Summary

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The goal of this study is to determine the effect of murottal and classical music on postoperative pain intensity and interleukin 6 levels in patients undergoing lower extremity orthopedic surgery with spinal anesthesia. This study also aims to evaluate whether these therapies can help reduce pain and influence the body's inflammatory response.

Main questions to be answered:

Can murottal or classical music reduce postoperative pain intensity in patients? Can the use of murottal or classical music lower the levels of interleukin 6, an inflammatory marker, in patients after lower extremity orthopedic surgery?

Participants will:

Listen to murottal or classical music during their lower extremity orthopedic surgery with spinal anesthesia.

Measure pain intensity and interleukin 6 levels before and after the intervention to assess the effect of the therapy.

Undergo routine checkups to ensure the safety and success of the therapy. This study aims to provide a deeper understanding of the use of non-pharmacological therapies such as murottal and classical music in managing pain and the inflammatory response in patients after orthopedic surgery.

Detailed Description

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This study aims to explore the impact of murottal (recitations of Islamic verses) and classical music on postoperative pain intensity and interleukin 6 levels in patients undergoing lower extremity orthopedic surgery with spinal anesthesia. Murottal and classical music are considered non-pharmacological interventions and have been suggested to have a calming effect that may help reduce pain and manage inflammation.

During the study, participants will be randomly assigned to receive either murottal, classical music, or standard postoperative care. Participants in the murottal group will listen to selected recitations durante operation, while participants in the classical music group will listen to classical music compositions.

Pain intensity will be assessed using a numeric rating scale (NRS) both before and after the intervention. Interleukin 6 levels, an inflammatory marker, will be measured using blood samples taken at the same intervals.

The goal is to determine whether these therapeutic interventions can help reduce pain and inflammation, as indicated by interleukin 6 levels, compared to standard care alone. Regular check-ups will be conducted to monitor safety and ensure the success of the therapy.

The findings of this study will help provide insights into the potential use of non-pharmacological interventions, such as murottal and classical music, in managing pain and inflammation in postoperative patients, with the potential to improve recovery outcomes

Conditions

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Pain Pain, Postoperative Inflammation Orthopedic Surgical Procedures

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This is a randomized, controlled trial with a parallel assignment study design. Participants will be randomly allocated to one of three groups:

Murottal Group: Participants will listen to selected Islamic recitations (murottal) as a therapeutic intervention during their postoperative recovery.

Classical Music Group: Participants will listen to selected classical music pieces to evaluate its impact on postoperative pain and inflammation.

Standard Care Group: Participants will receive standard postoperative care without any additional therapeutic interventions.

The goal is to assess and compare the effectiveness of murottal and classical music in reducing postoperative pain intensity and inflammation (measured by interleukin 6 levels), compared to the standard care. Randomization ensures unbiased distribution among the groups, and the parallel design enables simultaneous assessment of the interventions' effects in different groups.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
participant

Study Groups

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Arm 1: Murottal Therapy

Arm 1: Murottal Therapy

Intervention: Participants in this group will listen to selected recitations of Islamic verses (murottal) as a non-pharmacological intervention during their postoperative recovery.

Group Type EXPERIMENTAL

Murottal Therapy Intervention Name: Murottal (Islamic verse recitation)

Intervention Type DEVICE

To evaluate whether murottal recitations can reduce postoperative pain intensity and lower interleukin 6 levels, which are indicative of inflammation.

Arm 2: Classical Music Therapy

Intervention: Participants in this group will listen to selected classical music compositions during their recovery from lower extremity orthopedic surgery with spinal anesthesia.

Group Type EXPERIMENTAL

Classical Music Therapy Intervention Name: Classical Music Listening

Intervention Type DEVICE

To evaluate the impact of classical music on reducing postoperative pain intensity and interleukin 6 levels in the body, thereby managing inflammation.

Arm 3: Standard Care

Participants in this group will receive standard postoperative care following their surgery, without any additional interventions.

Group Type EXPERIMENTAL

Standard Care (in control arm)

Intervention Type OTHER

To serve as a control group no intervention

Interventions

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Murottal Therapy Intervention Name: Murottal (Islamic verse recitation)

To evaluate whether murottal recitations can reduce postoperative pain intensity and lower interleukin 6 levels, which are indicative of inflammation.

Intervention Type DEVICE

Classical Music Therapy Intervention Name: Classical Music Listening

To evaluate the impact of classical music on reducing postoperative pain intensity and interleukin 6 levels in the body, thereby managing inflammation.

Intervention Type DEVICE

Standard Care (in control arm)

To serve as a control group no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. All Muslim patients who are scheduled for elective lower extremity orthopedic surgery during the study period.
2. Patients aged 18 to 60 years.
3. Patients who agree to participate in the study.
4. Lower extremity orthopedic surgery (ORIF, OREF, and bone replacement) with a minimum surgery duration of 60 minutes.

Exclusion Criteria

1. Patients with consciousness disorders
2. Patients with neurological disorders
3. Patients with cognitive disorders
4. Patients with more than 3 spinal attempts
5. Patients with hearing impairments
6. BMI \< 18 and \> 39 kg/m²
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitas Jenderal Soedirman

OTHER

Sponsor Role lead

Responsible Party

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Guruh Perkasa

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Prof. Dr. Margono Soekarjo Hospital

Purwokerto, Central Java, Indonesia

Site Status RECRUITING

Countries

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Indonesia

Central Contacts

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Guruh Perkasa, Doctor

Role: CONTACT

+6285245883215

Facility Contacts

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Prof. Dr. Margono Soekarjo Hospital Prof. Dr. Margono Soekarjo Hospital

Role: primary

+62281-632708

References

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The Effect of Music Therapy on Pain, Anxiety and Vital Signs in Patients Undergoing Spinal Anaesthesia: A Randomized Controlled Trial Ibrahim Karagoz. et al.

Reference Type BACKGROUND

Related Links

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https://pubmed.ncbi.nlm.nih.gov/31356272/

The Effect of Perioperative Music on Medication Requirement and Hospital Length of Stay: A Meta-analysis

Other Identifiers

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420/08774

Identifier Type: -

Identifier Source: org_study_id