Development of Bone-vestibular Evoked Myogenic Potential
NCT ID: NCT06711653
Last Updated: 2024-12-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2022-11-07
2023-05-01
Brief Summary
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Detailed Description
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The study recruited 20 healthy adults (10 males and 10 females, aged 20-37 years), all of whom had normal otoscopic findings and no history of hearing issues. Ethical approval was obtained, and all participants provided informed consent.
Bone Conduction Vibrations (BCV):
Bone-conducted vibrations were generated using a SmartEP system and delivered via a Mini-Shaker transducer. Stimuli included 500 Hz and 750 Hz short-tone bursts (STB500 and STB750), calibrated to appropriate levels, with specific rise, plateau, and fall times.
Masking Conditions:
Masking sounds included speech noise (250-1000 Hz, calibrated at 100 dB SPL) and random interstimulus-interval tone bursts (rISITB, 500 Hz, 100 dB SPL).
Testing Procedure:
Vertical-axis BCV was delivered to the vertex (Cz) while participants maintained steady neck muscle tension in specified head positions. Electrodes were placed using a standard montage for cVEMP recording. Each side was tested under three masking conditions (NOM, SNM, rISITB) with a 24-hour interval between tests. Responses were recorded bilaterally and repeated for reproducibility.
Study Focus:
The study investigates the effects of different masking conditions on response characteristics, including latencies, amplitudes, and asymmetry ratios. The aim is to refine VEMP testing protocols, explore its potential for unilateral testing, and evaluate its applicability for specific vestibular organ assessments.
Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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Different Test Conditions
one test group with different test conditions
Vestibular evoke myogenic potential
routine Vestibular test
Interventions
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Vestibular evoke myogenic potential
routine Vestibular test
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* failed hearing screening test
* Having history of head or neck surgery
20 Years
40 Years
ALL
Yes
Sponsors
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Taipei City Hospital
OTHER_GOV
Responsible Party
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Principal Investigators
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Guo-She Lee
Role: PRINCIPAL_INVESTIGATOR
Taipei City Hospital
Locations
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Taipei City Hospital
Taipei, , Taiwan
Countries
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Other Identifiers
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TCHIRB-11103021-E-F
Identifier Type: -
Identifier Source: org_study_id