Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
31 participants
INTERVENTIONAL
2020-01-28
2023-06-08
Brief Summary
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* Does the timing of high-intensity interval exercise modulate the magnitude of the morning blood pressure surge?
* Do sex differences exist?
Participants came in and completed a bout of high-intensity interval exercise in the morning (8-10 am) and evening (5-7 pm) as well as a no exercise control, and ambulatory blood pressure was assessed for 24 hours afterwards.
Detailed Description
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Participants came in for 4 visits. The first visit was an introductory visit where chronotype, eligibility for exercise, and anthropometrics were measured. This was followed by a maximal incremental exercise test to determine aerobic capacity (i.e., V̇O2peak) on a cycle ergometer, and instrumentation of an ambulatory blood pressure monitor for familiarization during daily activities and sleep.
Intervention Visits:
Three intervention visits (control, morning exercise, and evening exercise) were completed. The order was randomized using and each visit was separated by a minimum of 36 hours. Each intervention visit began by obtaining the participant's resting blood pressure and heart rate and ended with the instrumentation of the ambulatory blood pressure monitor. No exercise was performed during the control visit. The morning exercise visit included a bout of high-intensity interval exercise between 8-10 am and the evening exercise visit included a bout of high-intensity interval exercise between 5-7 pm. The high-intensity interval exercise protocol consisted of a light intensity, 3-minute warm-up at 15% peak power followed by ten 1-minute work intervals at 80% of peak power, with each interval separated by 1-minute rest intervals at 15% peak power. A 3-minute cool down was performed at 15% peak power.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
PREVENTION
NONE
Study Groups
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Control
No exercise was performed and ambulatory blood pressure was assessed for 24 hours.
No interventions assigned to this group
Morning high-intensity interval exercise
High-intensity interval exercise was performed between 8-10 am and ambulatory blood pressure was assessed for 24 hours after.
Morning high-intensity interval exercise
High-intensity interval exercise was performed between 8-10 am
Evening high-intensity interval exercise
High-intensity interval exercise was performed between 5-7 pm and ambulatory blood pressure was assessed for 24 hours after.
Evening high-intensity interval exercise
High-intensity interval exercise was performed between 5-7 pm
Interventions
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Morning high-intensity interval exercise
High-intensity interval exercise was performed between 8-10 am
Evening high-intensity interval exercise
High-intensity interval exercise was performed between 5-7 pm
Eligibility Criteria
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Inclusion Criteria
* No history of known disease.
* None smokers.
* No use of chronic medications other than oral contraceptives.
Exclusion:
* \<18 years of age.
* \>50 years of age.
* Cardiovascular disease.
* Metabolic disease.
* History of smoking (within the past 3 months).
* Chronic medications (other than oral contraceptives).
18 Years
50 Years
ALL
Yes
Sponsors
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University of Guelph
OTHER
Responsible Party
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Philip Millar
Associate Professor
Principal Investigators
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Julian Bommarito, MSc
Role: STUDY_DIRECTOR
University of Guelph
Philip Millar, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Guelph
Locations
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University of Guelph
Guelph, Ontario, Canada
Countries
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References
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Bommarito J, Millar PJ. The effects of morning versus evening high-intensity interval exercise on the magnitude of the morning blood pressure surge. Appl Physiol Nutr Metab. 2025 Jan 1;50:1-11. doi: 10.1139/apnm-2024-0449.
Other Identifiers
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19-07-002
Identifier Type: -
Identifier Source: org_study_id