A Study to Evaluate the Long-Term Safety of Idecabtagene Vicleucel Treatment in Adults With Newly Diagnosed Multiple Myeloma in Korea

NCT ID: NCT06698887

Last Updated: 2024-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

15 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-11

Study Completion Date

2031-03-27

Brief Summary

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The purpose of this study is to monitor the long-term safety of participants who received idecabtagene vicleucel treatment as part of the KarMMa-9 (CA089-1043) Phase 3 clinical trial.

Detailed Description

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Conditions

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Multiple Myeloma

Keywords

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Multiple Myeloma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Participants receiving idecabtagene vicleucel

Idecabtagene vicleucel

Intervention Type DRUG

As per CA089-1043 study protocol

Interventions

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Idecabtagene vicleucel

As per CA089-1043 study protocol

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Adult participants ≥19 years of age
* Korean participants with newly diagnosed multiple myeloma who had a suboptimal response after autologous stem cell transplantation (ASCT) and who were treated with idecabtagene vicleucel (assigned to Arm A) in the KarMMa-9 trial (CA089-1043)
* Participants must understand and voluntarily sign and informed consent form (ICF) for the Korea long-term follow-up surveillance study prior to any surveillance-related procedures being conducted

Exclusion Criteria

* Participants who participate in KarMMa-9 trial (CA089-1043) but disagree with long-term follow-up surveillance in Korea
* Participants who are not possible to treat with Ide-cel within 9 days post-completion of lymphodepleting chemotherapy (LDC), if delays occur. However, depending on the participants recovery status, whether idecabtagene vicleucel is administered or not, should be discussed with a medical monitor
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bristol-Myers Squibb

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Bristol-Myers Squibb

Locations

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Chonnam National University Hwasun Hospital

Hwasun, Jeonranamdo, South Korea

Site Status RECRUITING

Seoul National University Hospital

Seoul, Seoul-teukbyeolsi [Seoul], South Korea

Site Status RECRUITING

Asan Medical Center

Seoul, Seoul-teukbyeolsi [Seoul], South Korea

Site Status RECRUITING

Samsung Medical Center

Seoul, Seoul-teukbyeolsi [Seoul], South Korea

Site Status RECRUITING

The Catholic Univ. of Korea Seoul St. Mary's Hospital

Seoul, Seoul-teukbyeolsi [Seoul], South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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BMS Study Connect Contact Center www.BMSStudyConnect.com

Role: CONTACT

Phone: 855-907-3286

Email: [email protected]

First line of the email MUST contain NCT # and Site #.

Role: CONTACT

Facility Contacts

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Sung Hoon Jung, Site 0041

Role: primary

SungSoo Yoon, Site 0039

Role: primary

Dok Hyun Yoon, Site 0040

Role: primary

Kihyun Kim, Site 0038

Role: primary

Chang Ki Min, Site 0043

Role: primary

Related Links

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Other Identifiers

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CA089-1081

Identifier Type: -

Identifier Source: org_study_id