The Number of Mesogastria Containing Metastatic Lymph Nodes Predicts Gastric Cancer Prognosis

NCT ID: NCT06697821

Last Updated: 2024-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

480 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-01

Study Completion Date

2024-05-01

Brief Summary

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To investigate the impact of the number of mesogastria containing metastatic lymph nodes on the prognosis of gastric cancer.

Detailed Description

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Previous studies have established the existence of the mesogastrium, dividing it into six sections. The mesogastrium is identified during surgery and utilized in surgical practice. The aim of the present study was to further investigate its role in gastric cancer prognosis.Between January 2014 and January 2018, patients from the Tongji Hospital were included in this post-hoc analysis, including data from a randomized clinical study (DCGC01; http://www.clinicaltrials.gov, NCT01978444). Mesogastria containing metastatic lymph nodes (LNs) were referred to as metastatic mesogastria. Pathology reports were examined to assess metastases in the mesogastrium. Survival was assessed using Kaplan-Meier curves and multivariable Cox models.

Conditions

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Gastric Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Interventions

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D2+CME

Whether to perform the whole mesogastric excision

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. older than 18, younger than 85
2. primary gastric adenocarcinoma confirmed by preoperative pathology
3. routine blood tests, liver and kidney functions and who health status score are within the range of tolerable surgery
4. it is expected to perform radical gastrectomy through d2+cme

Exclusion Criteria

1. pregnant or lactating women
2. severe mental disorder or language communication disorder
3. preoperative imaging examination or intraoperative exploration found that the patient had the following conditions: tumor involving surrounding organs requiring combined organ resection, distant organ metastasis or R0 resection could not be achieved
4. those who are not suitable for laparoscopic surgery (such as extensive adhesion caused by anterior abdominal surgery and pneumoperitoneum for various reasons).
5. concurrent malignancies at other sites
6. emergency surgery patients
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jichao Qin

OTHER

Sponsor Role lead

Responsible Party

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Jichao Qin

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Jichao Qin, M.D./Ph.D

Role: PRINCIPAL_INVESTIGATOR

Huazhong University of Science and Technology

Locations

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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Site Status

Countries

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China

Other Identifiers

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TJ-IRB202403050

Identifier Type: -

Identifier Source: org_study_id

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