Comparing Manual and Automatic Colonic Massage for Chronic Constipation.

NCT ID: NCT06695754

Last Updated: 2024-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-12-23

Study Completion Date

2024-12-31

Brief Summary

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The aim of this study is to do a systematic review and metanalysis of the scientific literature to compare the effectiveness of the manual vs the automatic colonic massage intervention in patients with chronic constipation.

Detailed Description

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Retrieval Strategy

* Computer retrieval of clinical literature on abdominal massage for constipation published between 1990 and December 2024 will be conducted in:

* NCBI PubMed.
* Research Gate.
* Google Scholar.
* Ovid.
* English retrieval terms included: colon, abdominal, constipation, bowel function, transit time, massage, and device.
* A cross-retrieval will be conducted to screen the literature that met the inclusion criteria.

Literature screening and data extraction

* The literature search will be independently performed by two researchers.
* Identified studies will be imported into EndNote×9 and Mendeley for organization.
* Articles will be evaluated based on predefined inclusion and exclusion criteria.
* Duplicates from various databases will be removed.
* Clearly irrelevant articles will be excluded based on their titles and abstracts.
* Full texts of the remaining studies will be thoroughly reviewed, and those that met the criteria will be included.
* The final dataset will be cross-verified.
* Discrepancies will be resolved through discussion or by involving a third researcher with a PhD for arbitration.
* Extracted data included:

* First author's name
* Publication year
* Study type
* Sample size
* Participant gender and age
* Interventions in both experimental and control groups
* Treatment duration and frequency
* Primary and secondary study outcomes
* Quality assessment of the studies
* Study characteristics, along with the study design, description of interventions (type of colon massage applied), and indices of evaluated results, will be organized using an Excel-based data extraction form.

Quality evaluation

* Quality assessment of the literature will be conducted using the "risk of bias" tool recommended by the Cochrane Handbook for Systematic Reviews (Rob2.0 and Robins-E). These tools evaluate various bias domains, including randomization, deviations from intended interventions, missing data, outcome measurement, and selective reporting. Each domain will be rated as having a high, unclear, or low risk of bias.
* Disagreements between the two researchers regarding the literature's conclusions will be resolved through discussion or by a third researcher.

Conditions

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Chronic Constipation

Keywords

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manual massage automatic massage colonic massage intermittent colonic exoperistalsis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Manual massage <90% over colon

Patients received a manual massage or treatment that reachs the ascending and descending colon for less than 90% of the total time of the treatment duration

No interventions assigned to this group

Manual massage >90% over colon

Patients received a manual massage or treatment that reachs the ascending and descending colon for 90% or more of the total time of treatment duration

No interventions assigned to this group

Automatic massage

Patients received a massage or treatment delivered with a medical device, that reachs the ascending and descending colon for 90% or more of the total time of treatment duration

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Study type:

* Clinical studies using abdominal/colon massage to treat constipation.
* Articles published between 1990 and till the day of literature search with original work (experimental and quasi-experimental ) or dealing with the application of colon massage to gastrointestinal function.
* Study subjects:

* Patients with constipation.
* Individuals of any gender, age and ethnicity.
* Interventions:

\- Manual or automatic colon massage treatment for constipation.
* Outcomes (including at least one of the following):

* Evacuation frequency.
* Quality of life parameters.
* Symptoms of constipation.
* Use of laxatives or enemas.
* Adverse events.

Exclusion Criteria

* No abstract available, reviews, conference abstracts, dissertations, registration documents, clinical experience summary analysis, animal experiments, etc.
* Studies where the treatment was non-colon specific.
* Studies involving invasive treatments.
* Other treatments intended to treat constipation such as surgical interventions, acupuncture, acupoint application, and others considered medicinal alternative therapies.
* Documents written in languages other than in English, German, Spanish, as well as other European languages, including Italian, French, and Portuguese.
* Incorrect or incomplete case data.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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usMIMA S.L.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Immaculada Herrero-Fresneda, PhD

Role: STUDY_DIRECTOR

usMIMA S.L.

Eugenia Delgado, PhD

Role: PRINCIPAL_INVESTIGATOR

usMIMA S.L.

Locations

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Usmima S.L.

Esplugues de Llobregat, Barcelona, Spain

Site Status

Countries

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Spain

Central Contacts

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Immaculada Herrero-Fresneda (Chief Scientific Officer), PhD

Role: CONTACT

Phone: +34 935106653

Email: [email protected]

Medical Writer

Role: CONTACT

Phone: +34 935106653

Email: [email protected]

Facility Contacts

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CSO

Role: primary

Medical Writer

Role: backup

Immaculada Herrero-Fresneda, PhD

Role: backup

Eugenia Delgado, PhD

Role: backup

Other Identifiers

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MOW_07_2024

Identifier Type: -

Identifier Source: org_study_id