The Effect of Non-invasive Auricular Acupoint Stimulation on Slow Transmission Constipation

NCT ID: NCT06680882

Last Updated: 2024-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

PHASE2

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-07

Study Completion Date

2025-11-01

Brief Summary

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Objective To examine the therapeutic effect and safety of non-invasive auricular acupoint stimulation application on patients with slow transmission constipation.

Methods In a randomized clinical trial, 60 patients diagnosed with slow transit constipation (STC), ranging in age from 40 to 75 years, were allocated into two distinct cohorts: a study group and a control group. The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride, while the control group, also consisting of 30 patients, was administered prucapride as a monotherapy. To assess the efficacy of the interventions, various parameters were monitored, including serum levels of Neuropeptide Y (NPY), nitric oxide (NO), fecal water content, and gastrointestinal (GI) transit. The comparative therapeutic outcomes were determined by calculating symptom scores.

Detailed Description

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Conditions

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Slow Transmission Constipation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

slow transmission constipation
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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study group

The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride

Group Type EXPERIMENTAL

Auricular Acupoint Stimulation +prucapride

Intervention Type OTHER

The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride

control group

also consisting of 30 patients, was administered prucapride as a monotherapy.

Group Type OTHER

prucapride

Intervention Type DRUG

was administered prucapride as a monotherapy

Interventions

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Auricular Acupoint Stimulation +prucapride

The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride

Intervention Type OTHER

prucapride

was administered prucapride as a monotherapy

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

\-

Exclusion Criteria

\-
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine

OTHER

Sponsor Role lead

Responsible Party

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Heng Deng

The Second hospital affiliated Anhui University of Chinese Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Heng Deng, Dr.

Role: CONTACT

+8613335510159

Other Identifiers

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No. 2023AH050848

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

AH2022056

Identifier Type: -

Identifier Source: org_study_id

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