Use of Determine Learning-based Cardiodynamicsgram (CDG) for Rapid and Precise Stratification of Chest Pain in Emergency Department

NCT ID: NCT06669884

Last Updated: 2024-11-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

8000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-28

Study Completion Date

2024-10-31

Brief Summary

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Chest pain accounts for 10-20 percent of all emergency department visits. The stratification of chest pain is always a challenge. Electrocardiograms (ECG) have been used in clinical practice for 100 years, which is too important to be replaced due to its advantages of non-invasive, simple, rapid and inexpensive. ECG contains numerous signals derived from depolarization and repolarization of cardiomyocytes. However, the interpretation of ECG hasn't improved much in a hundred years. Based on determine-learning, Cong W's team developed an technique called "cardiodynamicsgram (CDG)", which is an outstanding method to identify myocardial ischemia. This study will further investigate the accuracy of CDG in stratification of patients with chest pain in Emergency department.

Detailed Description

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Conditions

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Chest Pain Acute Coronary Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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machine learning algorithm

machine learning algorithm based on ECG features

Cardiodynamicsgram (CDG)

Intervention Type OTHER

Cardiodynamicsgram (CDG) technique

Interventions

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Cardiodynamicsgram (CDG)

Cardiodynamicsgram (CDG) technique

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* aged 18 years or older
* Those with suspected ACS who have symptoms of acute chest pain, visiting in the emergency department

Exclusion Criteria

* Those who diagnosed with ST-segment elevation myocardial infarction (STEMI)
* Those with hemodynamic instability (cardiogenic shock, cardiac arrest)
* Those with malignant arrhythmias(ventricular tachycardia, ventricular fibrillation, third-degree atrioventricular block)
* Those with aortic coarctation, or acute pulmonary embolism
* Those who has an unanalysable ECG report due to loosened leads, unstable baseline, or signal interference, etc.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Qilu Hospital of Shandong University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yuguo Chen, Professor

Role: PRINCIPAL_INVESTIGATOR

Qliu Hospital of Shandong University

Locations

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Qilu Hospital of Shandong University

Jinan, Shandong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Jiaojiao Pang, Doctor

Role: CONTACT

0086-0531-82165674

Facility Contacts

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Jiaojiao Pang, Doctor

Role: primary

0086-0531-82165674

Other Identifiers

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QLEmer-CDG-1

Identifier Type: -

Identifier Source: org_study_id

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