Small Changes Clinical Weight Loss Trial

NCT ID: NCT06668272

Last Updated: 2024-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-01

Study Completion Date

2025-11-01

Brief Summary

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The purpose of this study is to assess the effectiveness of the Small Changes program in facilitating weight loss and to assess treatment effects on body composition, blood markers of metabolic health, and blood pressure, and to assess attrition and compliance

Detailed Description

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Conditions

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Obesity

Keywords

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Small Changes weight loss

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Small Changes program

Group Type EXPERIMENTAL

Small Changes program

Intervention Type BEHAVIORAL

Participants will be asked to track their compliance with their Small Changes diet plan using a simple checklist record . Participants will be asked to follow their diet plan every day. They are encouraged to create a diet plan that is as close to their current diet as possible. Meal options include make-from-scratch recipes, quick "grab-and-go" options,and restaurant options. There may be some time involved in learning the recipes and the routine of their new diet. It also may alter their grocery spending and habits somewhat

Standard behavioral therapy for weight loss

Group Type ACTIVE_COMPARATOR

Standard behavioral therapy for weight loss

Intervention Type BEHAVIORAL

Participants will be provided guidance on cutting and counting calories, setting goals, reading labels, and portion sizes.

Interventions

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Small Changes program

Participants will be asked to track their compliance with their Small Changes diet plan using a simple checklist record . Participants will be asked to follow their diet plan every day. They are encouraged to create a diet plan that is as close to their current diet as possible. Meal options include make-from-scratch recipes, quick "grab-and-go" options,and restaurant options. There may be some time involved in learning the recipes and the routine of their new diet. It also may alter their grocery spending and habits somewhat

Intervention Type BEHAVIORAL

Standard behavioral therapy for weight loss

Participants will be provided guidance on cutting and counting calories, setting goals, reading labels, and portion sizes.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Body Mass Index greater than or equal to 25
* Stable weight with less than a 5% body weight change in the past 3 months.
* Willingness and ability to follow a written dietary plan.
* Ambulatory and capable of attending bi-weekly in-person and phone appointments.
* Must reside in the geographic area for the duration of the 12-week study.
* Clearance for weight loss by their health care provider.

Exclusion Criteria

* Pregnant or lactating.
* Acute medical conditions such as kidney disease, liver disease, pancreatitis, or cancer.
* A history of bariatric surgery or gastrointestinal resection.
* Current use of anti-obesity medications or diabetes medications, such as Glucagon-like peptide-1 receptor agonists (GLP-1RAs), that induce weight loss.
* A history of commercial weight loss program participation within the last six months.
* A history of anorexia nervosa or other eating disorders.
* A history of anxiety or depression.
* Extreme dietary restrictions or allergies that limit the ability to follow the weight loss plan.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The University of Texas Health Science Center, Houston

OTHER

Sponsor Role lead

Responsible Party

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Leah Whigham

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Leah Whigham, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Locations

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The University of Texas Health Science Center at Houston

Houston, Texas, United States

Site Status

Texas Tech University

Lubbock, Texas, United States

Site Status

Countries

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United States

Central Contacts

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Leah Whigham, PhD

Role: CONTACT

Phone: (915) 975-8517

Email: [email protected]

Juan Aguilera

Role: CONTACT

Phone: (915) 975-8520

Email: [email protected]

Facility Contacts

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Leah Whigham, PhD

Role: primary

Juan Aguilera

Role: backup

Nikhil Dhurandhar, PhD

Role: primary

Gaurav Kudchadkar

Role: backup

Other Identifiers

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HSC-SPH-24-0430

Identifier Type: -

Identifier Source: org_study_id