This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.
NCT ID: NCT06641011
Last Updated: 2024-10-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
104 participants
INTERVENTIONAL
2023-07-31
2026-10-30
Brief Summary
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Detailed Description
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Randomization of molar teeth into six groups according to the restoration time, dental restorative material type, and conditions:
Conditions
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Study Design
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RANDOMIZED
PARALLEL
Group 1: Restoration one week after silver fluoride application (n=72) Subgroup 1: Resin-based fissure sealant (n=36) Subgroup 2: Glass ionomer-based fissure sealant (n=36) Group 2: Immediate restoration after silver fluoride application (n=144) Subgroup 1: Blot-drying silver fluoride with cotton pellet followed by resin-based fissure sealant (n=36) Subgroup 2: Blot-drying silver fluoride with cotton pellet followed by glass ionomer-based fissure sealant (n=36) Subgroup 3: Rinsing silver fluoride off and air-drying of fissures followed by resin-based fissure sealant (n=36) Subgroup 4: Rinsing silver fluoride off and blot-drying of fissures followed by glass ionomer-based fissure sealant (n=36)
PREVENTION
NONE
Study Groups
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Resin based fissure sealant restoration one week after silver fluoride (AgF) application
Resin-based fissure sealant restoration one week after silver fluoride (AgF) application
Resin based fissure sealant restoration one week after silver fluoride (AgF) application
Resin based fissure sealant restoration one week after silver fluoride (AgF) application
Immediate resin based fissure sealant after blot drying silver fluoride (AgF) application
Immediate resin based fissure sealant after blot drying silver fluoride (AgF) application
Immediate restoration (resin- based) after blot-drying silver fluoride application
Blot-drying silver fluoride with cotton pellet followed by resin-based fissure sealant
Immediate GI-based fissure sealant after rinsing silver fluoride application
Immediate GI-based fissure sealant after rinsing silver fluoride application
Immediate restoration (GIC) after rinsing silver fluoride application
Rinsing silver fluoride off and blot-drying of fissures followed by glass ionomer-based fissure sealant
Immediate GI-based fissure sealant after blot-drying of silver fluoride application
Immediate GI-based fissure sealant after blot-drying of silver fluoride application
Immediate restoration (GI- based) after blot-drying silver fluoride application
Blot-drying silver fluoride with cotton pellet followed by glass ionomer-based fissure sealant
Immediate resin-based fissure sealant after rinsing of silver fluoride application
Immediate resin-based fissure sealant after rinsing of silver fluoride application
Immediate restoration (Resin based) after rinsing silver fluoride application
Rinsing silver fluoride off followed by resin-based fissure sealant
GI-based fissure sealant restoration one week after silver fluoride (AgF) application
GI-based fissure sealant restoration one week after silver fluoride (AgF) application
GI- based fissure sealant restoration one week after silver fluoride (AgF) application
GI- based fissure sealant restoration one week after silver fluoride (AgF) application
Interventions
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Immediate restoration (resin- based) after blot-drying silver fluoride application
Blot-drying silver fluoride with cotton pellet followed by resin-based fissure sealant
Immediate restoration (GI- based) after blot-drying silver fluoride application
Blot-drying silver fluoride with cotton pellet followed by glass ionomer-based fissure sealant
Immediate restoration (Resin based) after rinsing silver fluoride application
Rinsing silver fluoride off followed by resin-based fissure sealant
Immediate restoration (GIC) after rinsing silver fluoride application
Rinsing silver fluoride off and blot-drying of fissures followed by glass ionomer-based fissure sealant
Resin based fissure sealant restoration one week after silver fluoride (AgF) application
Resin based fissure sealant restoration one week after silver fluoride (AgF) application
GI- based fissure sealant restoration one week after silver fluoride (AgF) application
GI- based fissure sealant restoration one week after silver fluoride (AgF) application
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients with at least one permanent molar diagnosed with molar incisor hypomineralization based on EAPD guidelines.
* Fully erupted teeth with ICDAS I or II lesions that necessitate the application of fissure sealants.
* Teeth displaying demarcated opacities on the occlusal surface and at least one additional surface.
Exclusion Criteria
* Patients currently receiving orthodontic treatment.
* Patients who are uncooperative during dental procedures.
* Teeth affected by dental fluorosis or enamel defects associated with specific syndromes.
* Children with systemic conditions requiring ongoing medication.
6 Years
14 Years
ALL
Yes
Sponsors
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Hacettepe University
OTHER
Responsible Party
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Elif Ballikaya
Associated Professor
Principal Investigators
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Elif Ballikaya, DDS, PhD
Role: PRINCIPAL_INVESTIGATOR
Hacettepe University
Zafer Cehreli, DDS, PhD
Role: PRINCIPAL_INVESTIGATOR
Hacettepe University
Locations
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Hacettepe University Faculty of Dentistry, Department of Pediatric Dentistry
Ankara, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Related Links
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Other Identifiers
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TDH-2024-21181
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
TDH-2024-21181
Identifier Type: -
Identifier Source: org_study_id
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