ChatGPT-4 for Surgical Site Infection Detection From Electronic Health Records After Colorectal Surgery.

NCT ID: NCT06626399

Last Updated: 2025-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-15

Study Completion Date

2025-11-30

Brief Summary

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Epidemiological surveillance is one of the eight core components of the World Health Organization Infection Prevention and Control Programmes. These include surveillance programmes for surgical site infection (SSI).

At present, for SSI surveillance, infection control teams perform a manual time-consuming work, which could make a transition to automated surveillance leveraging the new information technology.

This study aimed to evaluate the ability of ChatGPT-4o to detect surgical site infection at the three anatomical levels.

Detailed Description

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Healthcare-associated infections (HAIs) have a negative impact on patient health, represent a significant healthcare and economic burden on healthcare systems and are considered the most preventable cause of serious adverse events in hospitalised patients.

Epidemiological surveillance is one of the eight core components of the World Health Organization (WHO) Infection Prevention and Control Programmes. These include surveillance programmes for surgical site infection (SSI), which have proven to be effective in all types of surgery and in a variety of settings.

For a programme to be effective, surveillance for HCAIs must be active, prospective and continuous, comprising a surveillance period up to 30-90 days post-intervention, to cover the high rate of SSIs detected after discharge.

At present, infection control teams perform a manual, prospective, time-consuming and almost artisanal work, which should make a transition to automated or semi-automated surveillance that leverages the possibilities offered by today\'s information technology.

The evolution of surveillance systems should benefit from this new possibilities offered by artificial intelligence, allowing automated detection of suspected SSI adverse events from clinical course text, microbiology reports or coding of diagnoses, procedures, complications and readmissions.

This study aims to evaluate the ability of ChatGPT to detect surgical site infections (SSI) at the three anatomical levels described by the CDC.

The study will retrospectively compare the results of the AI chatbot in diagnosing SSI, trained using the US CDC definition criteria, with a large cohort of elective colorectal surgery patients already evaluated through a nationwide nosocomial infection surveillance system, which will be the comparative gold standard.

Conditions

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Surgical Site Infection

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients assessed for SSI using the standard manual surveillance method

Patients undergoing colorectal surgery enrolled in the nationwide SSI surveillance programme and assessed for SSI using the standard manual surveillance method.

Diagnosis of SSI

Intervention Type DIAGNOSTIC_TEST

Diagnosis of SSI by manual system in colorectal surgery procedures enrolled in the SSI surveillance programme.

Patients assessed for SSI by Open IA's ChatGPT 4 chatbot

Patients undergoing colorectal surgery enrolled in the nationwide SSI surveillance programme and assessed for SSI using the Open IA's ChatGPT 4 chatbot.

Diagnosis of SSI

Intervention Type DIAGNOSTIC_TEST

Diagnosis of SSI by manual system in colorectal surgery procedures enrolled in the SSI surveillance programme.

Interventions

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Diagnosis of SSI

Diagnosis of SSI by manual system in colorectal surgery procedures enrolled in the SSI surveillance programme.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Elective colorectal resection

Exclusion Criteria

* Emergency surgery
* Infection present at operation
* Previous intestinal stoma
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital de Granollers

OTHER

Sponsor Role lead

Responsible Party

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Josep M Badia

Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Hospital General de Granollers

Granollers, Barcelona, Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Josep Badia, MD, PhD

Role: CONTACT

670702099

Facility Contacts

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Josep M Badia

Role: primary

670702099

Other Identifiers

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Infect-IA-3

Identifier Type: -

Identifier Source: org_study_id

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