Bioequivalence Study Between YHP2305 and YHR2404 in Healthy Volunteers

NCT ID: NCT06613139

Last Updated: 2024-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-06

Study Completion Date

2024-10-24

Brief Summary

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An open-label, randomized, single-dose, oral administration, 2-sequence, 2- period, crossover study to evaluate bioequivalence between YHP2305 and YHR2404 in healthy subjects

Detailed Description

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Subjects in group A will be administered comparator and YHP2305 by crossover design on day 1, 8.

Subjects in group B will be administered YHP2305 and comparator by crossover design on day 1, 8.

Conditions

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Healthy Volunteers

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Crossover Assignment two-way crossover
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Group A(RT)

17 subjects, Cross-over, Single dose of YHR2404 on day 1, Single dose of YHP2305 on day 8

Group Type EXPERIMENTAL

YHP2305

Intervention Type DRUG

Test drug: YHP2305 Comparator: YHR2404

YHR2404

Intervention Type DRUG

Test drug: YHP2305 comparator: YHR2404

Group B(TR)

17 subjects, Cross-over, Single dose of YHP2305 on day 1, Single dose of YHR2404 on day 8

Group Type EXPERIMENTAL

YHP2305

Intervention Type DRUG

Test drug: YHP2305 Comparator: YHR2404

YHR2404

Intervention Type DRUG

Test drug: YHP2305 comparator: YHR2404

Interventions

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YHP2305

Test drug: YHP2305 Comparator: YHR2404

Intervention Type DRUG

YHR2404

Test drug: YHP2305 comparator: YHR2404

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Those who are 19 years old or older at the screening visit
* Those whose weight is over 50kg(male), over 45kg(female) and their body mass index (BMI) shall be between 18.0 kg/m2 and 30.0 kg/m2
* Those who express their voluntary consent to participate in the trial by signing a written consent
* Those who are judged eligible to participate in the trial by the principal investigator(or delegated investigators) after screening test

Exclusion Criteria

* Those who have participated in a bioequivalence study or other clinical trials and have been administered with investigational products in 6 months prior to the first administration.
* Others who are judged ineligible to participate in the trial by the principal investigator.
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Yuhan Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Taegon Hong

Role: PRINCIPAL_INVESTIGATOR

Locations

Locations

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Bumin Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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YHP2305-101

Identifier Type: -

Identifier Source: org_study_id

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